(29 nodes) Toll Like Receptor 9 (TLR9) Cascade network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_06091	Polyubiquitin. (305 aa)
	HCAG_00050	BZIP domain-containing protein. (511 aa)
	HCAG_00181	Protein kinase domain-containing protein. (343 aa)
	HCAG_00216	Protein phosphatase PP2A regulatory subunit A. (613 aa)
	HCAG_00709	Metallophos domain-containing protein. (505 aa)
	HCAG_00722	Uncharacterized protein. (208 aa)
	HCAG_01013	TRAF-type domain-containing protein. (392 aa)
	HCAG_02220	Protein kinase domain-containing protein. (668 aa)
	HCAG_03030	Uncharacterized protein. (634 aa)
	HCAG_03260	Protein kinase domain-containing protein. (298 aa)
	HCAG_03461	Protein kinase byr1. (541 aa)
	HCAG_03908	Uncharacterized protein. (625 aa)
	HCAG_03950	APH domain-containing protein. (240 aa)
	HCAG_04659	Uncharacterized protein. (73 aa)
	HCAG_04969	Serine/threonine-protein phosphatase. (329 aa)
	HCAG_05236	Protein kinase domain-containing protein. (369 aa)
	HCAG_05250	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (367 aa)
	HCAG_05301	Uncharacterized protein. (645 aa)
	HCAG_05371	Uncharacterized protein. (319 aa)
	HCAG_05600	TYR_PHOSPHATASE_2 domain-containing protein. (264 aa)
	HCAG_06566	Ubiquitin/79aa fusion protein. (154 aa)
	HCAG_06788	APH domain-containing protein. (388 aa)
	HCAG_06114	BZIP domain-containing protein. (337 aa)
	HCAG_06188	Uncharacterized protein. (611 aa)
	HCAG_06189	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (423 aa)
	HCAG_06305	Uncharacterized protein. (701 aa)
	HCAG_08451	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
	HCAG_08893	Uncharacterized protein. (558 aa)
	HCAG_09083	Uncharacterized protein. (147 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00050	HCAG_03030	A6QRP4	A6R073	BZIP domain-containing protein.	Uncharacterized protein.	0.642
HCAG_00050	HCAG_03260	A6QRP4	A6R0V3	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.970
HCAG_00050	HCAG_05236	A6QRP4	A6R6H8	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.970
HCAG_00050	HCAG_05250	A6QRP4	A6R6J2	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.632
HCAG_00050	HCAG_06114	A6QRP4	A6RAX6	BZIP domain-containing protein.	BZIP domain-containing protein.	0.816
HCAG_00050	HCAG_06189	A6QRP4	A6RB51	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.673
HCAG_00050	HCAG_08451	A6QRP4	A6RFN5	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.974
HCAG_00181	HCAG_03030	A6QS25	A6R073	Protein kinase domain-containing protein.	Uncharacterized protein.	0.602
HCAG_00181	HCAG_03260	A6QS25	A6R0V3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.611
HCAG_00181	HCAG_05236	A6QS25	A6R6H8	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.611
HCAG_00181	HCAG_05250	A6QS25	A6R6J2	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.600
HCAG_00181	HCAG_06189	A6QS25	A6RB51	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.931
HCAG_00181	HCAG_08451	A6QS25	A6RFN5	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.611
HCAG_00216	HCAG_00709	A6QS60	A6QTK3	Protein phosphatase PP2A regulatory subunit A.	Metallophos domain-containing protein.	0.952
HCAG_00216	HCAG_04969	A6QS60	A6R5R1	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase.	0.999
HCAG_00216	HCAG_06091	A6QS60	A6RAV3	Protein phosphatase PP2A regulatory subunit A.	Polyubiquitin.	0.613
HCAG_00216	HCAG_06566	A6QS60	A6R8C5	Protein phosphatase PP2A regulatory subunit A.	Ubiquitin/79aa fusion protein.	0.600
HCAG_00709	HCAG_00216	A6QTK3	A6QS60	Metallophos domain-containing protein.	Protein phosphatase PP2A regulatory subunit A.	0.952
HCAG_00709	HCAG_06091	A6QTK3	A6RAV3	Metallophos domain-containing protein.	Polyubiquitin.	0.433
HCAG_00709	HCAG_06566	A6QTK3	A6R8C5	Metallophos domain-containing protein.	Ubiquitin/79aa fusion protein.	0.557