(16 nodes) Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_09257	Uncharacterized protein. (216 aa)
	HCAG_00181	Protein kinase domain-containing protein. (343 aa)
	HCAG_00614	Uncharacterized protein. (372 aa)
	HCAG_00878	Thioredoxin; Belongs to the thioredoxin family. (122 aa)
	HCAG_02220	Protein kinase domain-containing protein. (668 aa)
	HCAG_02554	Uncharacterized protein. (240 aa)
	HCAG_03030	Uncharacterized protein. (634 aa)
	HCAG_03260	Protein kinase domain-containing protein. (298 aa)
	HCAG_03461	Protein kinase byr1. (541 aa)
	HCAG_03464	Arrestin_C domain-containing protein. (972 aa)
	HCAG_04424	Arrestin_N domain-containing protein. (111 aa)
	HCAG_05236	Protein kinase domain-containing protein. (369 aa)
	HCAG_05717	Zn(2)-C6 fungal-type domain-containing protein. (485 aa)
	HCAG_08451	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
	HCAG_08954	Fungal_trans domain-containing protein. (812 aa)
	HCAG_09025	Arrestin_N domain-containing protein. (571 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00181	HCAG_03030	A6QS25	A6R073	Protein kinase domain-containing protein.	Uncharacterized protein.	0.602
HCAG_00181	HCAG_03260	A6QS25	A6R0V3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.611
HCAG_00181	HCAG_05236	A6QS25	A6R6H8	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.611
HCAG_00181	HCAG_08451	A6QS25	A6RFN5	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.611
HCAG_00878	HCAG_02554	A6QU22	A6QYU7	Thioredoxin; Belongs to the thioredoxin family.	Uncharacterized protein.	0.532
HCAG_00878	HCAG_03464	A6QU22	A6R1F7	Thioredoxin; Belongs to the thioredoxin family.	Arrestin_C domain-containing protein.	0.532
HCAG_00878	HCAG_04424	A6QU22	A6R466	Thioredoxin; Belongs to the thioredoxin family.	Arrestin_N domain-containing protein.	0.532
HCAG_00878	HCAG_05717	A6QU22	A6R9S9	Thioredoxin; Belongs to the thioredoxin family.	Zn(2)-C6 fungal-type domain-containing protein.	0.532
HCAG_00878	HCAG_08954	A6QU22	A6RH37	Thioredoxin; Belongs to the thioredoxin family.	Fungal_trans domain-containing protein.	0.532
HCAG_00878	HCAG_09025	A6QU22	A6RHA8	Thioredoxin; Belongs to the thioredoxin family.	Arrestin_N domain-containing protein.	0.532
HCAG_00878	HCAG_09257	A6QU22	A6XPF3	Thioredoxin; Belongs to the thioredoxin family.	Uncharacterized protein.	0.532
HCAG_02220	HCAG_03030	A6QXW3	A6R073	Protein kinase domain-containing protein.	Uncharacterized protein.	0.752
HCAG_02220	HCAG_03260	A6QXW3	A6R0V3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.975
HCAG_02220	HCAG_03461	A6QXW3	A6R1F4	Protein kinase domain-containing protein.	Protein kinase byr1.	0.719
HCAG_02220	HCAG_05236	A6QXW3	A6R6H8	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.975
HCAG_02220	HCAG_08451	A6QXW3	A6RFN5	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.979
HCAG_02554	HCAG_00878	A6QYU7	A6QU22	Uncharacterized protein.	Thioredoxin; Belongs to the thioredoxin family.	0.532
HCAG_03030	HCAG_00181	A6R073	A6QS25	Uncharacterized protein.	Protein kinase domain-containing protein.	0.602
HCAG_03030	HCAG_02220	A6R073	A6QXW3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.752
HCAG_03030	HCAG_03461	A6R073	A6R1F4	Uncharacterized protein.	Protein kinase byr1.	0.688