(29 nodes) trans-Golgi Network Vesicle Budding network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05808	VHS domain-containing protein. (1345 aa)
	HCAG_05978	Uncharacterized protein. (138 aa)
	HCAG_06062	PX domain-containing protein. (356 aa)
	HCAG_07936	t-SNARE coiled-coil homology domain-containing protein. (393 aa)
	HCAG_08041	Protein YIP. (323 aa)
	HCAG_08352	Uncharacterized protein; Belongs to the synaptobrevin family. (273 aa)
	HCAG_04225	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1631 aa)
	HCAG_03480	Glyco_transf_20 domain-containing protein. (947 aa)
	HCAG_02894	Rab-GAP TBC domain-containing protein. (892 aa)
	HCAG_02643	SEC7 domain-containing protein. (1407 aa)
	POA1	ADP-ribose 1''-phosphate phosphatase; Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing; Belongs to the POA1 family. (254 aa)
	VPS10	Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10 family. (1477 aa)
	HCAG_01849	Uncharacterized protein. (371 aa)
	HCAG_01847	ADP-ribosylation factor. (723 aa)
	HCAG_01581	Glucoamylase. (564 aa)
	HCAG_01328	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (253 aa)
	HCAG_01154	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa)
	HCAG_00869	Adaptin_N domain-containing protein. (753 aa)
	HCAG_06932	PUM-HD domain-containing protein. (847 aa)
	HCAG_00820	Uncharacterized protein. (324 aa)
	HCAG_00618	UBA domain-containing protein. (834 aa)
	HCAG_00598	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family. (422 aa)
	HCAG_00157	AP-1 complex subunit gamma. (765 aa)
	HCAG_06406	Glyco_transf_20 domain-containing protein. (900 aa)
	HCAG_05268	Trehalose-6-phosphate synthase. (518 aa)
	HCAG_05220	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (186 aa)
	HCAG_05155	Uncharacterized protein. (281 aa)
	HCAG_05154	PUM-HD domain-containing protein. (352 aa)
	HCAG_05039	Uncharacterized protein. (723 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00157	HCAG_00598	A6QS01	A6QT92	AP-1 complex subunit gamma.	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.999
HCAG_00157	HCAG_00618	A6QS01	A6QTB2	AP-1 complex subunit gamma.	UBA domain-containing protein.	0.557
HCAG_00157	HCAG_00820	A6QS01	A6QTW4	AP-1 complex subunit gamma.	Uncharacterized protein.	0.652
HCAG_00157	HCAG_00869	A6QS01	A6QU13	AP-1 complex subunit gamma.	Adaptin_N domain-containing protein.	0.960
HCAG_00157	HCAG_01154	A6QS01	A6QUU8	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
HCAG_00157	HCAG_01328	A6QS01	A6QVC1	AP-1 complex subunit gamma.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.876
HCAG_00157	HCAG_01581	A6QS01	A6QW24	AP-1 complex subunit gamma.	Glucoamylase.	0.589
HCAG_00157	HCAG_01847	A6QS01	A6QWU0	AP-1 complex subunit gamma.	ADP-ribosylation factor.	0.908
HCAG_00157	HCAG_01849	A6QS01	A6QWU2	AP-1 complex subunit gamma.	Uncharacterized protein.	0.908
HCAG_00157	HCAG_04225	A6QS01	A6R3L7	AP-1 complex subunit gamma.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.974
HCAG_00157	HCAG_05039	A6QS01	A6R5Y1	AP-1 complex subunit gamma.	Uncharacterized protein.	0.945
HCAG_00157	HCAG_05220	A6QS01	A6R6G2	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.966
HCAG_00157	HCAG_05808	A6QS01	A6RA20	AP-1 complex subunit gamma.	VHS domain-containing protein.	0.933
HCAG_00157	HCAG_05978	A6QS01	A6RAJ0	AP-1 complex subunit gamma.	Uncharacterized protein.	0.608
HCAG_00157	HCAG_06062	A6QS01	A6RAS4	AP-1 complex subunit gamma.	PX domain-containing protein.	0.679
HCAG_00157	HCAG_08352	A6QS01	A6RFD6	AP-1 complex subunit gamma.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.691
HCAG_00157	VPS10	A6QS01	A6QWZ2	AP-1 complex subunit gamma.	Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10 family.	0.698
HCAG_00598	HCAG_00157	A6QT92	A6QS01	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.999
HCAG_00598	HCAG_00618	A6QT92	A6QTB2	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	UBA domain-containing protein.	0.645
HCAG_00598	HCAG_00869	A6QT92	A6QU13	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	Adaptin_N domain-containing protein.	0.838