(45 nodes) COPII-mediated vesicle transport network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_01014	Uncharacterized protein. (807 aa)
	HCAG_00844	Uncharacterized protein. (507 aa)
	HCAG_00843	GP-PDE domain-containing protein. (235 aa)
	HCAG_00248	Uncharacterized protein. (572 aa)
	HCAG_05252	Uncharacterized protein. (933 aa)
	HCAG_05443	Uncharacterized protein. (256 aa)
	HCAG_05444	Uncharacterized protein. (667 aa)
	HCAG_05598	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (270 aa)
	HCAG_06473	t-SNARE coiled-coil homology domain-containing protein. (355 aa)
	HCAG_06520	L-type lectin-like domain-containing protein. (415 aa)
	HCAG_06678	Vesicle-fusing ATPase. (805 aa)
	HCAG_06902	Uncharacterized protein. (70 aa)
	HCAG_06941	GTP-binding protein ypt1. (204 aa)
	HCAG_06017	Rab-GAP TBC domain-containing protein. (420 aa)
	HCAG_06246	DUF2263 domain-containing protein. (312 aa)
	HCAG_07326	Uncharacterized protein. (81 aa)
	HCAG_07503	V-SNARE coiled-coil homology domain-containing protein. (249 aa)
	HCAG_07797	ER-derived vesicles protein ERV14. (134 aa)
	HCAG_07936	t-SNARE coiled-coil homology domain-containing protein. (393 aa)
	HCAG_08222	Uncharacterized protein. (1463 aa)
	HCAG_08368	Serine/threonine-protein phosphatase. (307 aa)
	HCAG_08899	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (676 aa)
	HCAG_08927	GP-PDE domain-containing protein. (174 aa)
	HCAG_08928	ANK_REP_REGION domain-containing protein. (375 aa)
	HCAG_08938	Protein transport protein SEC13; Belongs to the WD repeat SEC13 family. (307 aa)
	HCAG_09029	SH3 domain-containing protein. (409 aa)
	HCAG_09294	SPX domain-containing protein. (165 aa)
	HCAG_05142	Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
	HCAG_05119	Protein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family. (1705 aa)
	HCAG_04840	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
	HCAG_04789	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (668 aa)
	HCAG_04403	Trafficking protein particle complex subunit BET3. (193 aa)
	HCAG_03970	Uncharacterized protein. (334 aa)
	HCAG_03891	L-type lectin-like domain-containing protein. (330 aa)
	HCAG_03779	Uncharacterized protein. (292 aa)
	HCAG_03764	WD_REPEATS_REGION domain-containing protein. (1265 aa)
	HCAG_03468	Uncharacterized protein. (596 aa)
	HCAG_03467	Uncharacterized protein. (270 aa)
	HCAG_03018	Uncharacterized protein. (702 aa)
	HCAG_03011	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (168 aa)
	HCAG_02864	Ysc84 domain-containing protein. (518 aa)
	HCAG_02546	Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. (254 aa)
	HCAG_01602	Uncharacterized protein. (118 aa)
	HCAG_01601	Uncharacterized protein. (952 aa)
	HCAG_01401	t-SNARE coiled-coil homology domain-containing protein. (173 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00248	HCAG_01014	A6QS92	A6QUF8	Uncharacterized protein.	Uncharacterized protein.	0.621
HCAG_00248	HCAG_01401	A6QS92	A6QVJ4	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.474
HCAG_00248	HCAG_02546	A6QS92	A6QYT9	Uncharacterized protein.	Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.	0.999
HCAG_00248	HCAG_03011	A6QS92	A6R054	Uncharacterized protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.999
HCAG_00248	HCAG_03467	A6QS92	A6R1G0	Uncharacterized protein.	Uncharacterized protein.	0.550
HCAG_00248	HCAG_03468	A6QS92	A6R1G1	Uncharacterized protein.	Uncharacterized protein.	0.550
HCAG_00248	HCAG_03764	A6QS92	A6R2A6	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.624
HCAG_00248	HCAG_03970	A6QS92	A6R2W2	Uncharacterized protein.	Uncharacterized protein.	0.599
HCAG_00248	HCAG_04403	A6QS92	A6R445	Uncharacterized protein.	Trafficking protein particle complex subunit BET3.	0.999
HCAG_00248	HCAG_04789	A6QS92	A6R581	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.623
HCAG_00248	HCAG_04840	A6QS92	A6R5D2	Uncharacterized protein.	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family.	0.583
HCAG_00248	HCAG_05119	A6QS92	A6R661	Uncharacterized protein.	Protein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family.	0.485
HCAG_00248	HCAG_05142	A6QS92	A6R684	Uncharacterized protein.	Protein transport protein sec22; Belongs to the synaptobrevin family.	0.638
HCAG_00248	HCAG_05443	A6QS92	A6R735	Uncharacterized protein.	Uncharacterized protein.	0.651
HCAG_00248	HCAG_05444	A6QS92	A6R736	Uncharacterized protein.	Uncharacterized protein.	0.651
HCAG_00248	HCAG_06473	A6QS92	A6R832	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.606
HCAG_00248	HCAG_06902	A6QS92	A6R9B1	Uncharacterized protein.	Uncharacterized protein.	0.999
HCAG_00248	HCAG_06941	A6QS92	A6R9F0	Uncharacterized protein.	GTP-binding protein ypt1.	0.978
HCAG_00248	HCAG_07326	A6QS92	A6RCG8	Uncharacterized protein.	Uncharacterized protein.	0.998
HCAG_00248	HCAG_07503	A6QS92	A6RCZ5	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.614