(30 nodes) HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RTC5	Restriction of telomere capping protein 5; May be involved in a process influencing telomere capping. Belongs to the RTC5 family. (682 aa)
	HCAG_07372	Uncharacterized protein. (415 aa)
	HCAG_07373	Uncharacterized protein. (390 aa)
	HCAG_07624	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (527 aa)
	HCAG_07683	Uncharacterized protein. (688 aa)
	HCAG_08077	Uncharacterized protein. (248 aa)
	HCAG_08383	J domain-containing protein. (365 aa)
	HCAG_04471	Uncharacterized protein. (574 aa)
	HCAG_04686	ATP-dependent molecular chaperone HSC82. (702 aa)
	HCAG_04853	DnaJ_C domain-containing protein. (111 aa)
	HCAG_05166	MARVEL domain-containing protein. (204 aa)
	HCAG_05209	Uncharacterized protein. (243 aa)
	HCAG_05385	Uncharacterized protein; Belongs to the heat shock protein 70 family. (504 aa)
	HCAG_06431	DnaJ_C domain-containing protein. (242 aa)
	HCAG_06612	Uncharacterized protein. (519 aa)
	HCAG_05818	Amidase domain-containing protein. (499 aa)
	HCAG_05994	Dynactin domain-containing protein. (1217 aa)
	HCAG_04433	TPR_REGION domain-containing protein. (464 aa)
	HCAG_03003	T5orf172 domain-containing protein. (469 aa)
	HCAG_02409	Amidase domain-containing protein. (624 aa)
	HCAG_02339	Uncharacterized protein. (501 aa)
	HCAG_01398	Heat shock 70 kDa protein 7. (311 aa)
	HCAG_01395	Amidase domain-containing protein. (381 aa)
	HCAG_01331	Uncharacterized protein. (455 aa)
	HCAG_01164	N-acetyltransferase domain-containing protein. (280 aa)
	HCAG_01102	Dynactin Arp1 p25 subunit. (198 aa)
	HCAG_00806	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family. (613 aa)
	HCAG_01004	Uncharacterized protein. (266 aa)
	HCAG_00720	Uncharacterized protein. (511 aa)
	HCAG_04450	Uncharacterized protein. (545 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00720	HCAG_01102	A6QTL4	A6QUP6	Uncharacterized protein.	Dynactin Arp1 p25 subunit.	0.746
HCAG_00720	HCAG_05209	A6QTL4	A6R6F1	Uncharacterized protein.	Uncharacterized protein.	0.690
HCAG_00720	HCAG_05994	A6QTL4	A6RAK6	Uncharacterized protein.	Dynactin domain-containing protein.	0.951
HCAG_00720	HCAG_06612	A6QTL4	A6R8H1	Uncharacterized protein.	Uncharacterized protein.	0.809
HCAG_00806	HCAG_01004	A6QTV0	A6QUE8	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.514
HCAG_00806	HCAG_01164	A6QTV0	A6QUV8	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	N-acetyltransferase domain-containing protein.	0.514
HCAG_00806	HCAG_03003	A6QTV0	A6R046	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	T5orf172 domain-containing protein.	0.514
HCAG_00806	HCAG_04433	A6QTV0	A6R475	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	TPR_REGION domain-containing protein.	0.615
HCAG_00806	HCAG_04471	A6QTV0	A6R4B3	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.925
HCAG_00806	HCAG_04686	A6QTV0	A6R4X8	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	ATP-dependent molecular chaperone HSC82.	0.954
HCAG_00806	HCAG_04853	A6QTV0	A6R5E5	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	DnaJ_C domain-containing protein.	0.805
HCAG_00806	HCAG_05166	A6QTV0	A6R6A8	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	MARVEL domain-containing protein.	0.514
HCAG_00806	HCAG_05385	A6QTV0	A6R6X7	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.402
HCAG_00806	HCAG_06431	A6QTV0	A6R7Z0	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	DnaJ_C domain-containing protein.	0.779
HCAG_00806	HCAG_07372	A6QTV0	A6RCL4	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.732
HCAG_00806	HCAG_07373	A6QTV0	A6RCL5	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.514
HCAG_00806	HCAG_08077	A6QTV0	A6REL2	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.514
HCAG_00806	HCAG_08383	A6QTV0	A6RFG7	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	J domain-containing protein.	0.932
HCAG_01004	HCAG_00806	A6QUE8	A6QTV0	Uncharacterized protein.	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	0.514
HCAG_01004	HCAG_01398	A6QUE8	A6QVJ1	Uncharacterized protein.	Heat shock 70 kDa protein 7.	0.514