(110 nodes) Translesion synthesis by POLK network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05003	Integrase catalytic domain-containing protein. (490 aa)
	HCAG_03390	Uncharacterized protein. (445 aa)
	HCAG_03517	Integrase catalytic domain-containing protein. (909 aa)
	HCAG_03564	Integrase catalytic domain-containing protein. (221 aa)
	HCAG_03629	Uncharacterized protein. (1496 aa)
	HCAG_03706	Uncharacterized protein. (1508 aa)
	HCAG_03739	Uncharacterized protein. (1618 aa)
	HCAG_03740	CCHC-type domain-containing protein. (804 aa)
	HCAG_03749	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1162 aa)
	HCAG_03956	Reverse transcriptase domain-containing protein. (554 aa)
	HCAG_03959	Uncharacterized protein. (1052 aa)
	HCAG_04057	Integrase catalytic domain-containing protein. (1753 aa)
	HCAG_04105	Uncharacterized protein. (1481 aa)
	HCAG_04125	Chromo domain-containing protein. (310 aa)
	HCAG_04640	Uncharacterized protein. (1373 aa)
	HCAG_04716	Uncharacterized protein. (433 aa)
	HCAG_04960	Uncharacterized protein. (1074 aa)
	HCAG_05005	Uncharacterized protein. (86 aa)
	HCAG_05350	Uncharacterized protein. (765 aa)
	HCAG_05468	Uncharacterized protein. (1088 aa)
	HCAG_05476	Uncharacterized protein. (899 aa)
	HCAG_05632	Uncharacterized protein. (218 aa)
	HCAG_06338	Integrase catalytic domain-containing protein. (1683 aa)
	HCAG_06345	Uncharacterized protein. (1515 aa)
	HCAG_06438	Uncharacterized protein. (1242 aa)
	HCAG_06566	Ubiquitin/79aa fusion protein. (154 aa)
	HCAG_06641	Uncharacterized protein. (524 aa)
	HCAG_06663	Uncharacterized protein. (1850 aa)
	HCAG_06705	Uncharacterized protein. (1196 aa)
	HCAG_06818	Uncharacterized protein. (216 aa)
	HCAG_06974	Uncharacterized protein. (1201 aa)
	HCAG_05655	Uncharacterized protein. (1271 aa)
	HCAG_05844	Reverse transcriptase domain-containing protein. (1172 aa)
	HCAG_06047	Reverse transcriptase domain-containing protein. (639 aa)
	HCAG_06091	Polyubiquitin. (305 aa)
	HCAG_06117	CCHC-type domain-containing protein. (983 aa)
	HCAG_06314	Uncharacterized protein. (1545 aa)
	HCAG_07152	Reverse transcriptase domain-containing protein. (805 aa)
	HCAG_07319	Integrase catalytic domain-containing protein. (1217 aa)
	HCAG_07449	Integrase catalytic domain-containing protein. (1449 aa)
	HCAG_07479	Uncharacterized protein. (1554 aa)
	HCAG_07484	Uncharacterized protein. (653 aa)
	HCAG_07487	Uncharacterized protein. (1499 aa)
	HCAG_07591	Uncharacterized protein. (356 aa)
	HCAG_07602	Integrase catalytic domain-containing protein. (1576 aa)
	HCAG_07728	C2H2-type domain-containing protein. (1067 aa)
	HCAG_07729	Uncharacterized protein. (279 aa)
	HCAG_07918	UmuC domain-containing protein. (373 aa)
	HCAG_08128	Reverse transcriptase domain-containing protein. (554 aa)
	HCAG_08194	Reverse transcriptase domain-containing protein. (653 aa)
	HCAG_08279	Uncharacterized protein. (1587 aa)
	HCAG_08402	Uncharacterized protein. (1584 aa)
	HCAG_08414	Uncharacterized protein. (276 aa)
	HCAG_08533	Reverse transcriptase domain-containing protein. (429 aa)
	HCAG_08564	Uncharacterized protein. (327 aa)
	HCAG_08572	Uncharacterized protein. (854 aa)
	HCAG_09285	RT_RNaseH domain-containing protein. (292 aa)
	HCAG_09237	Uncharacterized protein. (664 aa)
	HCAG_09225	Reverse transcriptase Ty1/copia-type domain-containing protein. (666 aa)
	HCAG_09079	Uncharacterized protein. (190 aa)
	HCAG_09030	Zds_C domain-containing protein. (844 aa)
	HCAG_09006	Reverse transcriptase Ty1/copia-type domain-containing protein. (1057 aa)
	HCAG_08768	Uncharacterized protein. (662 aa)
	HCAG_08731	Uncharacterized protein. (80 aa)
	HCAG_08608	Integrase catalytic domain-containing protein. (886 aa)
	HCAG_00136	Reverse transcriptase domain-containing protein. (291 aa)
	HCAG_00222	Uncharacterized protein. (1395 aa)
	HCAG_00280	Uncharacterized protein. (1584 aa)
	HCAG_00333	Uncharacterized protein. (1517 aa)
	HCAG_00335	Uncharacterized protein. (136 aa)
	HCAG_00455	Uncharacterized protein. (336 aa)
	HCAG_00469	Integrase catalytic domain-containing protein. (980 aa)
	HCAG_00475	Uncharacterized protein. (1520 aa)
	HCAG_00477	Uncharacterized protein. (345 aa)
	HCAG_00510	Uncharacterized protein. (1487 aa)
	HCAG_00914	Uncharacterized protein. (743 aa)
	HCAG_00917	Uncharacterized protein. (637 aa)
	HCAG_00920	Uncharacterized protein. (101 aa)
	HCAG_01036	Reverse transcriptase domain-containing protein. (433 aa)
	HCAG_01037	Integrase_H2C2 domain-containing protein. (186 aa)
	HCAG_01419	Integrase catalytic domain-containing protein. (1530 aa)
	HCAG_01421	Uncharacterized protein. (368 aa)
	HCAG_01423	Uncharacterized protein. (668 aa)
	HCAG_01460	Uncharacterized protein. (1414 aa)
	HCAG_01463	Integrase catalytic domain-containing protein. (527 aa)
	HCAG_01464	Reverse transcriptase domain-containing protein. (640 aa)
	HCAG_01532	Uncharacterized protein. (298 aa)
	HCAG_01635	Integrase catalytic domain-containing protein. (1497 aa)
	HCAG_01716	Uncharacterized protein. (267 aa)
	HCAG_01775	Chromo domain-containing protein. (344 aa)
	HCAG_01801	Uncharacterized protein. (865 aa)
	HCAG_01936	Uncharacterized protein. (1520 aa)
	HCAG_02026	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (549 aa)
	HCAG_02046	Uncharacterized protein. (61 aa)
	HCAG_02063	Integrase catalytic domain-containing protein. (1488 aa)
	HCAG_02379	Reverse transcriptase domain-containing protein. (1263 aa)
	HCAG_02388	Uncharacterized protein. (444 aa)
	HCAG_02551	Uncharacterized protein. (117 aa)
	HCAG_02740	Uncharacterized protein. (700 aa)
	HCAG_02836	Integrase catalytic domain-containing protein. (1488 aa)
	HCAG_02852	Integrase catalytic domain-containing protein. (857 aa)
	HCAG_02873	Uncharacterized protein. (1164 aa)
	HCAG_02942	Integrase catalytic domain-containing protein. (886 aa)
	HCAG_02954	Integrase catalytic domain-containing protein. (754 aa)
	HCAG_03122	RT_RNaseH domain-containing protein. (90 aa)
	HCAG_03161	Integrase catalytic domain-containing protein. (1672 aa)
	HCAG_03328	Uncharacterized protein. (1201 aa)
	HCAG_03340	Reverse transcriptase domain-containing protein. (363 aa)
	HCAG_03341	Integrase_H2C2 domain-containing protein. (217 aa)
	HCAG_03389	Integrase catalytic domain-containing protein. (845 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00136	HCAG_00914	A6QRY0	A6QU58	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.845
HCAG_00136	HCAG_00917	A6QRY0	A6QU61	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.497
HCAG_00136	HCAG_01463	A6QRY0	A6QVQ6	Reverse transcriptase domain-containing protein.	Integrase catalytic domain-containing protein.	0.757
HCAG_00136	HCAG_02740	A6QRY0	A6QZD3	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.843
HCAG_00136	HCAG_02954	A6QRY0	A6QZZ7	Reverse transcriptase domain-containing protein.	Integrase catalytic domain-containing protein.	0.868
HCAG_00136	HCAG_03341	A6QRY0	A6R134	Reverse transcriptase domain-containing protein.	Integrase_H2C2 domain-containing protein.	0.529
HCAG_00136	HCAG_05632	A6QRY0	A6R7M4	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.695
HCAG_00136	HCAG_08768	A6QRY0	A6RGK1	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.486
HCAG_00136	HCAG_09237	A6QRY0	A6XPD6	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.669
HCAG_00136	HCAG_09285	A6QRY0	A6XPH7	Reverse transcriptase domain-containing protein.	RT_RNaseH domain-containing protein.	0.949
HCAG_00222	HCAG_03564	A6QS66	A6R1Q6	Uncharacterized protein.	Integrase catalytic domain-containing protein.	0.518
HCAG_00469	HCAG_06818	A6QSW3	A6R927	Integrase catalytic domain-containing protein.	Uncharacterized protein.	0.518
HCAG_00914	HCAG_00136	A6QU58	A6QRY0	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.845
HCAG_00914	HCAG_01036	A6QU58	A6QUI0	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.746
HCAG_00914	HCAG_01464	A6QU58	A6QVQ7	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.460
HCAG_00914	HCAG_03340	A6QU58	A6R133	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.732
HCAG_00914	HCAG_03956	A6QU58	A6R2U8	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.704
HCAG_00914	HCAG_06047	A6QU58	A6RAQ9	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.626
HCAG_00914	HCAG_07152	A6QU58	A6RBZ4	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.676
HCAG_00914	HCAG_08128	A6QU58	A6RER3	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.703