(14 nodes) Cargo concentration in the ER network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_01014	Uncharacterized protein. (807 aa)
	HCAG_07797	ER-derived vesicles protein ERV14. (134 aa)
	HCAG_06520	L-type lectin-like domain-containing protein. (415 aa)
	HCAG_06473	t-SNARE coiled-coil homology domain-containing protein. (355 aa)
	HCAG_05444	Uncharacterized protein. (667 aa)
	HCAG_05443	Uncharacterized protein. (256 aa)
	HCAG_05252	Uncharacterized protein. (933 aa)
	HCAG_05142	Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
	HCAG_04840	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
	HCAG_04789	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (668 aa)
	HCAG_03970	Uncharacterized protein. (334 aa)
	HCAG_03891	L-type lectin-like domain-containing protein. (330 aa)
	HCAG_03468	Uncharacterized protein. (596 aa)
	HCAG_03467	Uncharacterized protein. (270 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01014	HCAG_03467	A6QUF8	A6R1G0	Uncharacterized protein.	Uncharacterized protein.	0.748
HCAG_01014	HCAG_03468	A6QUF8	A6R1G1	Uncharacterized protein.	Uncharacterized protein.	0.748
HCAG_01014	HCAG_03970	A6QUF8	A6R2W2	Uncharacterized protein.	Uncharacterized protein.	0.629
HCAG_01014	HCAG_04789	A6QUF8	A6R581	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.748
HCAG_01014	HCAG_04840	A6QUF8	A6R5D2	Uncharacterized protein.	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family.	0.700
HCAG_01014	HCAG_05142	A6QUF8	A6R684	Uncharacterized protein.	Protein transport protein sec22; Belongs to the synaptobrevin family.	0.639
HCAG_01014	HCAG_05252	A6QUF8	A6R6J4	Uncharacterized protein.	Uncharacterized protein.	0.872
HCAG_01014	HCAG_06473	A6QUF8	A6R832	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.673
HCAG_01014	HCAG_07797	A6QUF8	A6RDT9	Uncharacterized protein.	ER-derived vesicles protein ERV14.	0.602
HCAG_03467	HCAG_01014	A6R1G0	A6QUF8	Uncharacterized protein.	Uncharacterized protein.	0.748
HCAG_03467	HCAG_03891	A6R1G0	A6R2N3	Uncharacterized protein.	L-type lectin-like domain-containing protein.	0.491
HCAG_03467	HCAG_03970	A6R1G0	A6R2W2	Uncharacterized protein.	Uncharacterized protein.	0.663
HCAG_03467	HCAG_04840	A6R1G0	A6R5D2	Uncharacterized protein.	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family.	0.912
HCAG_03467	HCAG_05142	A6R1G0	A6R684	Uncharacterized protein.	Protein transport protein sec22; Belongs to the synaptobrevin family.	0.899
HCAG_03467	HCAG_05252	A6R1G0	A6R6J4	Uncharacterized protein.	Uncharacterized protein.	0.940
HCAG_03467	HCAG_05443	A6R1G0	A6R735	Uncharacterized protein.	Uncharacterized protein.	0.748
HCAG_03467	HCAG_05444	A6R1G0	A6R736	Uncharacterized protein.	Uncharacterized protein.	0.748
HCAG_03467	HCAG_06473	A6R1G0	A6R832	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.738
HCAG_03467	HCAG_06520	A6R1G0	A6R879	Uncharacterized protein.	L-type lectin-like domain-containing protein.	0.491
HCAG_03467	HCAG_07797	A6R1G0	A6RDT9	Uncharacterized protein.	ER-derived vesicles protein ERV14.	0.555