(23 nodes) Tryptophan catabolism network (Histoplasma capsulatum NAm1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	HCAG_01655	Aminotran_1_2 domain-containing protein. (420 aa)
	HCAG_00474	Aminotran_1_2 domain-containing protein. (641 aa)
	HCAG_00568	Uncharacterized protein. (492 aa)
	HCAG_00896	FAD_binding_3 domain-containing protein. (448 aa)
	HCAG_01148	Uncharacterized protein. (481 aa)
	HCAG_08907	FAD_binding_3 domain-containing protein. (376 aa)
	HCAG_08164	FAD_binding_3 domain-containing protein. (455 aa)
	HCAG_08086	Uncharacterized protein. (142 aa)
	HCAG_08085	Uncharacterized protein. (264 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (510 aa)
	HCAG_07561	FAD_binding_3 domain-containing protein. (419 aa)
	HCAG_06143	AIP3 domain-containing protein. (1021 aa)
	HCAG_05722	FAD_binding_3 domain-containing protein. (454 aa)
	HCAG_06862	FAD_binding_3 domain-containing protein. (465 aa)
	HCAG_06601	Uncharacterized protein. (352 aa)
	HCAG_05456	FAD_binding_3 domain-containing protein. (481 aa)
	HCAG_05314	CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (220 aa)
	HCAG_04617	Amino transferase. (532 aa)
	HCAG_03033	Uncharacterized protein. (325 aa)
	HCAG_02973	Uncharacterized protein. (391 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (192 aa)
	HCAG_02310	Aminotran_1_2 domain-containing protein. (540 aa)
	HCAG_02012	FAD_binding_3 domain-containing protein. (413 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA1	BNA4	A6QZE4	A6RDT4	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.859
BNA1	HCAG_01148	A6QZE4	A6QUU2	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.651
BNA1	HCAG_08085	A6QZE4	A6REM0	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.980
BNA1	HCAG_08086	A6QZE4	A6REM1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.793
BNA4	BNA1	A6RDT4	A6QZE4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.859
BNA4	HCAG_01148	A6RDT4	A6QUU2	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.637
BNA4	HCAG_01655	A6RDT4	A6QW98	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.964
BNA4	HCAG_07561	A6RDT4	A6RD53	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	FAD_binding_3 domain-containing protein.	0.615
BNA4	HCAG_08085	A6RDT4	A6REM0	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.992
BNA4	HCAG_08086	A6RDT4	A6REM1	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.808
HCAG_00568	HCAG_08085	A6QT62	A6REM0	Uncharacterized protein.	Uncharacterized protein.	0.445
HCAG_00568	HCAG_08086	A6QT62	A6REM1	Uncharacterized protein.	Uncharacterized protein.	0.445
HCAG_00896	HCAG_08085	A6QU40	A6REM0	FAD_binding_3 domain-containing protein.	Uncharacterized protein.	0.445
HCAG_00896	HCAG_08086	A6QU40	A6REM1	FAD_binding_3 domain-containing protein.	Uncharacterized protein.	0.445
HCAG_01148	BNA1	A6QUU2	A6QZE4	Uncharacterized protein.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.651
HCAG_01148	BNA4	A6QUU2	A6RDT4	Uncharacterized protein.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.637
HCAG_01148	HCAG_01655	A6QUU2	A6QW98	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.504
HCAG_01148	HCAG_04617	A6QUU2	A6R4Q9	Uncharacterized protein.	Amino transferase.	0.909
HCAG_01148	HCAG_08085	A6QUU2	A6REM0	Uncharacterized protein.	Uncharacterized protein.	0.942
HCAG_01148	HCAG_08086	A6QUU2	A6REM1	Uncharacterized protein.	Uncharacterized protein.	0.451