(16 nodes) Synthesis of very long-chain fatty acyl-CoAs network (Histoplasma capsulatum NAm1)

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Your Input:
	HCAG_02169	Elongation of fatty acids protein. (548 aa)
	HCAG_04512	Uncharacterized protein. (331 aa)
	HCAG_05332	BZIP domain-containing protein. (299 aa)
	HCAG_06943	WD_REPEATS_REGION domain-containing protein. (1184 aa)
	HCAG_06958	AMP-binding domain-containing protein. (709 aa)
	HCAG_05786	BZIP domain-containing protein. (520 aa)
	HCAG_07127	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
	HCAG_07510	BZIP domain-containing protein. (421 aa)
	HCAG_07688	Uncharacterized protein. (222 aa)
	HCAG_08180	AMP-binding domain-containing protein. (623 aa)
	HCAG_08337	Uncharacterized protein. (224 aa)
	HCAG_08638	AMP-binding domain-containing protein. (680 aa)
	HCAG_00436	Elongation of fatty acids protein. (193 aa)
	HCAG_00578	Uncharacterized protein. (523 aa)
	HCAG_01309	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (108 aa)
	HCAG_01670	S5A_REDUCTASE domain-containing protein. (197 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00436	HCAG_01309	A6QST0	A6QVA2	Elongation of fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.910
HCAG_00436	HCAG_07127	A6QST0	A6RBW9	Elongation of fatty acids protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.931
HCAG_01309	HCAG_00436	A6QVA2	A6QST0	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Elongation of fatty acids protein.	0.910
HCAG_01309	HCAG_01670	A6QVA2	A6QWB3	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	S5A_REDUCTASE domain-containing protein.	0.785
HCAG_01309	HCAG_07127	A6QVA2	A6RBW9	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.964
HCAG_01309	HCAG_08337	A6QVA2	A6RFC1	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.573
HCAG_01670	HCAG_01309	A6QWB3	A6QVA2	S5A_REDUCTASE domain-containing protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.785
HCAG_01670	HCAG_05332	A6QWB3	A6R6S4	S5A_REDUCTASE domain-containing protein.	BZIP domain-containing protein.	0.783
HCAG_01670	HCAG_05786	A6QWB3	A6R9Z8	S5A_REDUCTASE domain-containing protein.	BZIP domain-containing protein.	0.783
HCAG_01670	HCAG_07127	A6QWB3	A6RBW9	S5A_REDUCTASE domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.891
HCAG_01670	HCAG_07510	A6QWB3	A6RD02	S5A_REDUCTASE domain-containing protein.	BZIP domain-containing protein.	0.783
HCAG_01670	HCAG_07688	A6QWB3	A6RDI0	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.785
HCAG_01670	HCAG_08337	A6QWB3	A6RFC1	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.836
HCAG_05332	HCAG_01670	A6R6S4	A6QWB3	BZIP domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.783
HCAG_05332	HCAG_07127	A6R6S4	A6RBW9	BZIP domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.589
HCAG_05332	HCAG_08337	A6R6S4	A6RFC1	BZIP domain-containing protein.	Uncharacterized protein.	0.573
HCAG_05786	HCAG_01670	A6R9Z8	A6QWB3	BZIP domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.783
HCAG_05786	HCAG_07127	A6R9Z8	A6RBW9	BZIP domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.589
HCAG_05786	HCAG_08337	A6R9Z8	A6RFC1	BZIP domain-containing protein.	Uncharacterized protein.	0.573
HCAG_06958	HCAG_08180	A6R9G7	A6REW5	AMP-binding domain-containing protein.	AMP-binding domain-containing protein.	0.943