(102 nodes) Golgi-to-ER retrograde transport network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05142	Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
	HCAG_04945	Uncharacterized protein. (925 aa)
	HCAG_04740	Uncharacterized protein. (752 aa)
	HCAG_04734	Uncharacterized protein. (724 aa)
	HCAG_04688	Uncharacterized protein. (515 aa)
	HCAG_04656	Uncharacterized protein. (342 aa)
	HCAG_04650	Uncharacterized protein. (731 aa)
	HCAG_04614	Uncharacterized protein. (577 aa)
	HCAG_04571	Uncharacterized protein. (655 aa)
	HCAG_04543	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (999 aa)
	HCAG_04524	Uncharacterized protein. (528 aa)
	HCAG_04366	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa)
	HCAG_04305	Uncharacterized protein. (194 aa)
	HCAG_04212	Uncharacterized protein. (804 aa)
	HCAG_04083	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1035 aa)
	HCAG_04056	C2H2-type domain-containing protein. (755 aa)
	HCAG_04014	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (801 aa)
	HCAG_03962	Uncharacterized protein. (772 aa)
	HCAG_03793	Uncharacterized protein. (742 aa)
	HCAG_03779	Uncharacterized protein. (292 aa)
	HCAG_03691	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (202 aa)
	HCAG_03397	C2H2-type domain-containing protein. (636 aa)
	HCAG_03377	Uncharacterized protein. (184 aa)
	HCAG_03099	Uncharacterized protein. (450 aa)
	HCAG_03077	Uncharacterized protein. (829 aa)
	HCAG_02986	Uncharacterized protein. (380 aa)
	HCAG_02915	Arf-GAP domain-containing protein. (382 aa)
	HCAG_02892	Uncharacterized protein. (809 aa)
	HCAG_02765	Uncharacterized protein. (130 aa)
	HCAG_02725	Uncharacterized protein. (324 aa)
	HCAG_02695	Uncharacterized protein. (812 aa)
	HCAG_02643	SEC7 domain-containing protein. (1407 aa)
	HCAG_02515	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (598 aa)
	HCAG_02398	C2H2-type domain-containing protein. (743 aa)
	HCAG_02288	Uncharacterized protein. (638 aa)
	HCAG_02251	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (516 aa)
	HCAG_02249	Uncharacterized protein. (806 aa)
	HCAG_02239	Uncharacterized protein. (915 aa)
	POA1	ADP-ribose 1''-phosphate phosphatase; Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing; Belongs to the POA1 family. (254 aa)
	HCAG_01857	Uncharacterized protein. (303 aa)
	HCAG_00266	Uncharacterized protein. (790 aa)
	HCAG_00275	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1674 aa)
	HCAG_00317	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1740 aa)
	HCAG_00359	Uncharacterized protein. (809 aa)
	HCAG_00379	TPR_REGION domain-containing protein. (2034 aa)
	HCAG_00481	Uncharacterized protein. (79 aa)
	HCAG_00504	Uncharacterized protein. (416 aa)
	HCAG_00515	Uncharacterized protein; Belongs to the EMP24/GP25L family. (605 aa)
	HCAG_00720	Uncharacterized protein. (511 aa)
	HCAG_00733	Uncharacterized protein. (396 aa)
	HCAG_00743	Uncharacterized protein. (145 aa)
	HCAG_00834	Uncharacterized protein. (235 aa)
	HCAG_00919	Uncharacterized protein. (616 aa)
	HCAG_01102	Dynactin Arp1 p25 subunit. (198 aa)
	HCAG_01514	Uncharacterized protein. (699 aa)
	HCAG_01612	Uncharacterized protein. (809 aa)
	HCAG_01632	Uncharacterized protein. (250 aa)
	HCAG_01748	Uncharacterized protein. (850 aa)
	HCAG_01814	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (956 aa)
	HCAG_01831	GOLD domain-containing protein. (70 aa)
	HCAG_01847	ADP-ribosylation factor. (723 aa)
	HCAG_01849	Uncharacterized protein. (371 aa)
	HCAG_07949	C2H2-type domain-containing protein. (694 aa)
	HCAG_07846	Uncharacterized protein. (767 aa)
	HCAG_07610	Uncharacterized protein. (760 aa)
	HCAG_07385	Uncharacterized protein. (496 aa)
	HCAG_09147	Uncharacterized protein. (132 aa)
	HCAG_09146	Uncharacterized protein. (331 aa)
	HCAG_09071	Uncharacterized protein. (791 aa)
	HCAG_08999	Uncharacterized protein. (784 aa)
	HCAG_08922	Uncharacterized protein. (802 aa)
	HCAG_08894	C2H2-type domain-containing protein. (623 aa)
	HCAG_08766	Uncharacterized protein. (839 aa)
	HCAG_08740	Uncharacterized protein. (782 aa)
	HCAG_08724	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (846 aa)
	HCAG_08698	Uncharacterized protein. (299 aa)
	HCAG_08675	t-SNARE coiled-coil homology domain-containing protein. (416 aa)
	HCAG_08619	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (958 aa)
	HCAG_08535	Uncharacterized protein. (806 aa)
	HCAG_08523	Uncharacterized protein. (694 aa)
	HCAG_08497	Uncharacterized protein. (676 aa)
	HCAG_08438	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (296 aa)
	HCAG_08186	Arf-GAP domain-containing protein. (481 aa)
	HCAG_08129	Uncharacterized protein. (806 aa)
	HCAG_07033	GOLD domain-containing protein. (221 aa)
	HCAG_06196	Lysophospholipase. (643 aa)
	HCAG_06118	BZIP domain-containing protein. (895 aa)
	HCAG_05994	Dynactin domain-containing protein. (1217 aa)
	HCAG_06952	Uncharacterized protein. (607 aa)
	HCAG_06941	GTP-binding protein ypt1. (204 aa)
	HCAG_06921	ER lumen protein-retaining receptor. (125 aa)
	HCAG_06780	Uncharacterized protein. (781 aa)
	HCAG_06678	Vesicle-fusing ATPase. (805 aa)
	HCAG_06661	Uncharacterized protein. (805 aa)
	HCAG_06631	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (794 aa)
	HCAG_06612	Uncharacterized protein. (519 aa)
	HCAG_06584	Uncharacterized protein. (804 aa)
	HCAG_05563	GOLD domain-containing protein. (180 aa)
	HCAG_05346	Uncharacterized protein. (723 aa)
	HCAG_05338	Uncharacterized protein. (605 aa)
	HCAG_05330	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (886 aa)
	HCAG_05255	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (812 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00275	HCAG_00317	A6QSB9	A6QSG1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.528
HCAG_00275	HCAG_02643	A6QSB9	A6QZ36	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	SEC7 domain-containing protein.	0.402
HCAG_00275	HCAG_04083	A6QSB9	A6R375	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.431
HCAG_00275	HCAG_04212	A6QSB9	A6R3K4	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.409
HCAG_00275	HCAG_04543	A6QSB9	A6R4I5	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.432
HCAG_00275	HCAG_08619	A6QSB9	A6RG53	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.430
HCAG_00317	HCAG_00275	A6QSG1	A6QSB9	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.528
HCAG_00317	HCAG_02515	A6QSG1	A6QYQ8	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.528
HCAG_00317	HCAG_02643	A6QSG1	A6QZ36	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	SEC7 domain-containing protein.	0.591
HCAG_00317	HCAG_04014	A6QSG1	A6R306	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.650
HCAG_00317	HCAG_04083	A6QSG1	A6R375	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.744
HCAG_00317	HCAG_04212	A6QSG1	A6R3K4	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.599
HCAG_00317	HCAG_04543	A6QSG1	A6R4I5	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.760
HCAG_00317	HCAG_05255	A6QSG1	A6R6J7	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.858
HCAG_00317	HCAG_05994	A6QSG1	A6RAK6	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Dynactin domain-containing protein.	0.499
HCAG_00317	HCAG_06631	A6QSG1	A6R8J0	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.548
HCAG_00317	HCAG_08619	A6QSG1	A6RG53	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.645
HCAG_00317	POA1	A6QSG1	A6QXU0	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	ADP-ribose 1''-phosphate phosphatase; Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing; Belongs to the POA1 family.	0.424
HCAG_00515	HCAG_00743	A6QT09	A6QTN7	Uncharacterized protein; Belongs to the EMP24/GP25L family.	Uncharacterized protein.	0.624
HCAG_00515	HCAG_01814	A6QT09	A6QWQ7	Uncharacterized protein; Belongs to the EMP24/GP25L family.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.651