(17 nodes) RHOD GTPase cycle network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_04752	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (266 aa)
	HCAG_04097	Uncharacterized protein. (1689 aa)
	HCAG_03438	ANK_REP_REGION domain-containing protein. (239 aa)
	HCAG_03028	CRIB domain-containing protein. (698 aa)
	HCAG_03019	Non-specific serine/threonine protein kinase. (881 aa)
	HCAG_02257	Uncharacterized protein. (585 aa)
	HCAG_01241	Protein Rho3. (206 aa)
	HCAG_01182	Uncharacterized protein. (575 aa)
	HCAG_01053	Uncharacterized protein. (187 aa)
	HCAG_00777	Uncharacterized protein. (1158 aa)
	HCAG_00741	Uncharacterized protein. (582 aa)
	HCAG_00107	Uncharacterized protein. (197 aa)
	HCAG_05560	Uncharacterized protein. (192 aa)
	HCAG_06740	Aldolase_II domain-containing protein. (270 aa)
	HCAG_06757	Aldolase_II domain-containing protein. (232 aa)
	HCAG_08789	Aldolase_II domain-containing protein. (301 aa)
	HCAG_09016	Non-specific serine/threonine protein kinase. (904 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00107	HCAG_00741	A6QRV1	A6QTN5	Uncharacterized protein.	Uncharacterized protein.	0.411
HCAG_00107	HCAG_00777	A6QRV1	A6QTS1	Uncharacterized protein.	Uncharacterized protein.	0.999
HCAG_00107	HCAG_01053	A6QRV1	A6QUJ7	Uncharacterized protein.	Uncharacterized protein.	0.421
HCAG_00107	HCAG_01182	A6QRV1	A6QUX6	Uncharacterized protein.	Uncharacterized protein.	0.738
HCAG_00107	HCAG_02257	A6QRV1	A6QY00	Uncharacterized protein.	Uncharacterized protein.	0.403
HCAG_00107	HCAG_03019	A6QRV1	A6R062	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.554
HCAG_00107	HCAG_03028	A6QRV1	A6R071	Uncharacterized protein.	CRIB domain-containing protein.	0.411
HCAG_00107	HCAG_04097	A6QRV1	A6R389	Uncharacterized protein.	Uncharacterized protein.	0.623
HCAG_00107	HCAG_04752	A6QRV1	A6R544	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.519
HCAG_00107	HCAG_09016	A6QRV1	A6RH99	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.554
HCAG_00741	HCAG_00107	A6QTN5	A6QRV1	Uncharacterized protein.	Uncharacterized protein.	0.411
HCAG_00741	HCAG_01053	A6QTN5	A6QUJ7	Uncharacterized protein.	Uncharacterized protein.	0.411
HCAG_00741	HCAG_01241	A6QTN5	A6QV34	Uncharacterized protein.	Protein Rho3.	0.411
HCAG_00741	HCAG_04752	A6QTN5	A6R544	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.660
HCAG_00741	HCAG_05560	A6QTN5	A6R7F2	Uncharacterized protein.	Uncharacterized protein.	0.411
HCAG_00777	HCAG_00107	A6QTS1	A6QRV1	Uncharacterized protein.	Uncharacterized protein.	0.999
HCAG_00777	HCAG_01053	A6QTS1	A6QUJ7	Uncharacterized protein.	Uncharacterized protein.	0.999
HCAG_00777	HCAG_01182	A6QTS1	A6QUX6	Uncharacterized protein.	Uncharacterized protein.	0.992
HCAG_00777	HCAG_01241	A6QTS1	A6QV34	Uncharacterized protein.	Protein Rho3.	0.999
HCAG_00777	HCAG_03019	A6QTS1	A6R062	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.927