(16 nodes) Sealing of the nuclear envelope (NE) by ESCRT-III network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_08344	Uncharacterized protein. (227 aa)
	HCAG_08288	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	HCAG_06719	Uncharacterized protein. (412 aa)
	HCAG_06510	Uncharacterized protein. (495 aa)
	HCAG_05491	Uncharacterized protein. (223 aa)
	HCAG_05411	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family. (353 aa)
	HCAG_05270	AAA domain-containing protein; Belongs to the AAA ATPase family. (843 aa)
	HCAG_05138	Uncharacterized protein. (384 aa)
	HCAG_03771	AAA domain-containing protein. (978 aa)
	HCAG_03753	Uncharacterized protein. (684 aa)
	HCAG_03088	AAA domain-containing protein. (577 aa)
	HCAG_02484	Uncharacterized protein. (228 aa)
	HCAG_02068	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (420 aa)
	HCAG_01966	Uncharacterized protein. (211 aa)
	HCAG_01762	AAA domain-containing protein. (709 aa)
	HCAG_01781	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (406 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01762	HCAG_01966	A6QWK5	A6QX59	AAA domain-containing protein.	Uncharacterized protein.	0.515
HCAG_01762	HCAG_02484	A6QWK5	A6QYM7	AAA domain-containing protein.	Uncharacterized protein.	0.532
HCAG_01762	HCAG_05411	A6QWK5	A6R703	AAA domain-containing protein.	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	0.481
HCAG_01762	HCAG_05491	A6QWK5	A6R783	AAA domain-containing protein.	Uncharacterized protein.	0.492
HCAG_01762	HCAG_06510	A6QWK5	A6R869	AAA domain-containing protein.	Uncharacterized protein.	0.518
HCAG_01762	HCAG_06719	A6QWK5	A6R8S8	AAA domain-containing protein.	Uncharacterized protein.	0.698
HCAG_01762	HCAG_08344	A6QWK5	A6RFC8	AAA domain-containing protein.	Uncharacterized protein.	0.634
HCAG_01781	HCAG_02068	A6QWM4	A6QXG1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.998
HCAG_01781	HCAG_03753	A6QWM4	A6R295	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.420
HCAG_01781	HCAG_05270	A6QWM4	A6R6L2	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.401
HCAG_01781	HCAG_05411	A6QWM4	A6R703	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	0.600
HCAG_01781	HCAG_05491	A6QWM4	A6R783	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.594
HCAG_01781	HCAG_06719	A6QWM4	A6R8S8	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.536
HCAG_01781	HCAG_08288	A6QWM4	A6RF72	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.998
HCAG_01966	HCAG_01762	A6QX59	A6QWK5	Uncharacterized protein.	AAA domain-containing protein.	0.515
HCAG_01966	HCAG_02484	A6QX59	A6QYM7	Uncharacterized protein.	Uncharacterized protein.	0.986
HCAG_01966	HCAG_03088	A6QX59	A6R0D1	Uncharacterized protein.	AAA domain-containing protein.	0.515
HCAG_01966	HCAG_03771	A6QX59	A6R2B3	Uncharacterized protein.	AAA domain-containing protein.	0.515
HCAG_01966	HCAG_05270	A6QX59	A6R6L2	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.685
HCAG_01966	HCAG_05411	A6QX59	A6R703	Uncharacterized protein.	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	0.994