(98 nodes) Factors involved in megakaryocyte development and platelet production network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_08691	PH domain-containing protein. (1290 aa)
	HCAG_00266	Uncharacterized protein. (790 aa)
	HCAG_00275	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1674 aa)
	HCAG_00317	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1740 aa)
	HCAG_00359	Uncharacterized protein. (809 aa)
	HCAG_00379	TPR_REGION domain-containing protein. (2034 aa)
	HCAG_00481	Uncharacterized protein. (79 aa)
	HCAG_00504	Uncharacterized protein. (416 aa)
	HCAG_00625	Uncharacterized protein. (546 aa)
	HCAG_00834	Uncharacterized protein. (235 aa)
	HCAG_00884	Uncharacterized protein. (630 aa)
	HCAG_00919	Uncharacterized protein. (616 aa)
	HCAG_01124	GATA-type domain-containing protein. (529 aa)
	HCAG_01134	C2H2-type domain-containing protein. (556 aa)
	HCAG_01168	Uncharacterized protein. (158 aa)
	HCAG_01169	Uncharacterized protein. (98 aa)
	HCAG_01183	Protein rho2. (199 aa)
	HCAG_01275	Uncharacterized protein. (261 aa)
	HCAG_01287	Uncharacterized protein. (91 aa)
	HCAG_01288	Uncharacterized protein. (69 aa)
	HCAG_01514	Uncharacterized protein. (699 aa)
	HCAG_01612	Uncharacterized protein. (809 aa)
	HCAG_01632	Uncharacterized protein. (250 aa)
	HCAG_01748	Uncharacterized protein. (850 aa)
	HCAG_02157	N-acetyltransferase domain-containing protein. (269 aa)
	HCAG_02239	Uncharacterized protein. (915 aa)
	HCAG_02249	Uncharacterized protein. (806 aa)
	HCAG_02288	Uncharacterized protein. (638 aa)
	HCAG_02398	C2H2-type domain-containing protein. (743 aa)
	HCAG_02485	Uncharacterized protein. (743 aa)
	HCAG_02515	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (598 aa)
	HCAG_02695	Uncharacterized protein. (812 aa)
	HCAG_02725	Uncharacterized protein. (324 aa)
	HCAG_02765	Uncharacterized protein. (130 aa)
	HCAG_02892	Uncharacterized protein. (809 aa)
	HCAG_02986	Uncharacterized protein. (380 aa)
	HCAG_03077	Uncharacterized protein. (829 aa)
	HCAG_03099	Uncharacterized protein. (450 aa)
	HCAG_03377	Uncharacterized protein. (184 aa)
	HCAG_03397	C2H2-type domain-containing protein. (636 aa)
	HCAG_03499	Uncharacterized protein. (852 aa)
	HCAG_03793	Uncharacterized protein. (742 aa)
	HCAG_03889	cAMP-dependent protein kinase type 2. (368 aa)
	HCAG_03921	Uncharacterized protein. (196 aa)
	HCAG_03962	Uncharacterized protein. (772 aa)
	HCAG_04014	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (801 aa)
	HCAG_04056	C2H2-type domain-containing protein. (755 aa)
	HCAG_04083	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1035 aa)
	HCAG_04353	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (343 aa)
	HCAG_04543	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (999 aa)
	HCAG_04571	Uncharacterized protein. (655 aa)
	HCAG_04614	Uncharacterized protein. (577 aa)
	HCAG_04650	Uncharacterized protein. (731 aa)
	HCAG_04656	Uncharacterized protein. (342 aa)
	HCAG_04688	Uncharacterized protein. (515 aa)
	HCAG_04734	Uncharacterized protein. (724 aa)
	HCAG_04740	Uncharacterized protein. (752 aa)
	HCAG_04752	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (266 aa)
	ADK2	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (275 aa)
	HCAG_04794	Uncharacterized protein; Belongs to the adenylate kinase family. (72 aa)
	HCAG_04945	Uncharacterized protein. (925 aa)
	HCAG_05255	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (812 aa)
	HCAG_05338	Uncharacterized protein. (605 aa)
	HCAG_05346	Uncharacterized protein. (723 aa)
	HCAG_05488	cAMP-dependent protein kinase regulatory subunit. (148 aa)
	HCAG_06631	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (794 aa)
	HCAG_06661	Uncharacterized protein. (805 aa)
	HCAG_06780	Uncharacterized protein. (781 aa)
	HCAG_06952	Uncharacterized protein. (607 aa)
	HCAG_05796	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (267 aa)
	HCAG_05797	Uncharacterized protein. (494 aa)
	HCAG_05973	GATA-type domain-containing protein. (510 aa)
	HCAG_06041	Uncharacterized protein; Belongs to the DOCK family. (1780 aa)
	HCAG_06082	Uncharacterized protein. (502 aa)
	HCAG_06118	BZIP domain-containing protein. (895 aa)
	HCAG_06157	Uncharacterized protein. (358 aa)
	HCAG_06247	RRN9 domain-containing protein. (481 aa)
	HCAG_07020	Uncharacterized protein. (1080 aa)
	HCAG_07385	Uncharacterized protein. (496 aa)
	HCAG_07610	Uncharacterized protein. (760 aa)
	HCAG_07846	Uncharacterized protein. (767 aa)
	HCAG_07949	C2H2-type domain-containing protein. (694 aa)
	HCAG_07966	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1174 aa)
	HCAG_08129	Uncharacterized protein. (806 aa)
	HCAG_08251	Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
	HCAG_08497	Uncharacterized protein. (676 aa)
	HCAG_08523	Uncharacterized protein. (694 aa)
	HCAG_08535	Uncharacterized protein. (806 aa)
	HCAG_08619	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (958 aa)
	HCAG_08698	Uncharacterized protein. (299 aa)
	HCAG_08740	Uncharacterized protein. (782 aa)
	HCAG_08766	Uncharacterized protein. (839 aa)
	HCAG_08894	C2H2-type domain-containing protein. (623 aa)
	HCAG_08922	Uncharacterized protein. (802 aa)
	HCAG_08999	Uncharacterized protein. (784 aa)
	HCAG_09071	Uncharacterized protein. (791 aa)
	HCAG_09146	Uncharacterized protein. (331 aa)
	HCAG_09147	Uncharacterized protein. (132 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00275	HCAG_00317	A6QSB9	A6QSG1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.528
HCAG_00275	HCAG_04083	A6QSB9	A6R375	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.431
HCAG_00275	HCAG_04543	A6QSB9	A6R4I5	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.432
HCAG_00275	HCAG_07966	A6QSB9	A6REA1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.504
HCAG_00275	HCAG_08619	A6QSB9	A6RG53	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.430
HCAG_00317	HCAG_00275	A6QSG1	A6QSB9	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.528
HCAG_00317	HCAG_02515	A6QSG1	A6QYQ8	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.528
HCAG_00317	HCAG_04014	A6QSG1	A6R306	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.650
HCAG_00317	HCAG_04083	A6QSG1	A6R375	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.744
HCAG_00317	HCAG_04543	A6QSG1	A6R4I5	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.760
HCAG_00317	HCAG_05255	A6QSG1	A6R6J7	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.858
HCAG_00317	HCAG_06631	A6QSG1	A6R8J0	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.548
HCAG_00317	HCAG_07966	A6QSG1	A6REA1	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.882
HCAG_00317	HCAG_08619	A6QSG1	A6RG53	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.645
HCAG_01134	HCAG_01287	A6QUS8	A6QV80	C2H2-type domain-containing protein.	Uncharacterized protein.	0.675
HCAG_01134	HCAG_01288	A6QUS8	A6QV81	C2H2-type domain-containing protein.	Uncharacterized protein.	0.675
HCAG_01134	HCAG_02157	A6QUS8	A6QXQ0	C2H2-type domain-containing protein.	N-acetyltransferase domain-containing protein.	0.675
HCAG_01134	HCAG_03921	A6QUS8	A6R2R3	C2H2-type domain-containing protein.	Uncharacterized protein.	0.675
HCAG_01134	HCAG_08251	A6QUS8	A6RF35	C2H2-type domain-containing protein.	Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.	0.999
HCAG_01168	HCAG_01169	A6QUW2	A6QUW3	Uncharacterized protein.	Uncharacterized protein.	0.518