(11 nodes) Histidine metabolism network (Histoplasma capsulatum NAm1)

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	HCAG_01026	Uncharacterized protein. (867 aa)
	HCAG_02035	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (549 aa)
	HCAG_02357	Histidinol dehydrogenase. (1148 aa)
	HCAG_06360	ATP phosphoribosyltransferase. (324 aa)
	HCAG_06729	Histidinol-phosphate aminotransferase. (321 aa)
	HCAG_06766	N2227 domain-containing protein. (421 aa)
	HCAG_05962	Aminotran_5 domain-containing protein. (422 aa)
	HCAG_06205	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
	HCAG_08023	Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (278 aa)
	HCAG_08367	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa)
	HCAG_08550	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (243 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01026	HCAG_02357	A6QUH0	A6QYA0	Uncharacterized protein.	Histidinol dehydrogenase.	0.902
HCAG_01026	HCAG_05962	A6QUH0	A6RAH4	Uncharacterized protein.	Aminotran_5 domain-containing protein.	0.936
HCAG_02035	HCAG_02357	A6QXC8	A6QYA0	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol dehydrogenase.	0.999
HCAG_02035	HCAG_06360	A6QXC8	A6R7R9	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	ATP phosphoribosyltransferase.	0.992
HCAG_02035	HCAG_06729	A6QXC8	A6R8T8	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol-phosphate aminotransferase.	0.992
HCAG_02035	HCAG_08023	A6QXC8	A6REF8	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.	0.677
HCAG_02035	HCAG_08550	A6QXC8	A6RFY4	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.995
HCAG_02357	HCAG_01026	A6QYA0	A6QUH0	Histidinol dehydrogenase.	Uncharacterized protein.	0.902
HCAG_02357	HCAG_02035	A6QYA0	A6QXC8	Histidinol dehydrogenase.	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	0.999
HCAG_02357	HCAG_06205	A6QYA0	A6RB67	Histidinol dehydrogenase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.416
HCAG_02357	HCAG_06360	A6QYA0	A6R7R9	Histidinol dehydrogenase.	ATP phosphoribosyltransferase.	0.999
HCAG_02357	HCAG_06729	A6QYA0	A6R8T8	Histidinol dehydrogenase.	Histidinol-phosphate aminotransferase.	0.999
HCAG_02357	HCAG_08023	A6QYA0	A6REF8	Histidinol dehydrogenase.	Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.	0.997
HCAG_02357	HCAG_08367	A6QYA0	A6RFF1	Histidinol dehydrogenase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.416
HCAG_02357	HCAG_08550	A6QYA0	A6RFY4	Histidinol dehydrogenase.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.999
HCAG_05962	HCAG_01026	A6RAH4	A6QUH0	Aminotran_5 domain-containing protein.	Uncharacterized protein.	0.936
HCAG_06205	HCAG_02357	A6RB67	A6QYA0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Histidinol dehydrogenase.	0.416
HCAG_06205	HCAG_08367	A6RB67	A6RFF1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.902
HCAG_06360	HCAG_02035	A6R7R9	A6QXC8	ATP phosphoribosyltransferase.	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	0.992
HCAG_06360	HCAG_02357	A6R7R9	A6QYA0	ATP phosphoribosyltransferase.	Histidinol dehydrogenase.	0.999