(40 nodes) Amino sugar and nucleotide sugar metabolism network (Histoplasma capsulatum NAm1)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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Your Input:
	HCAG_00064	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (549 aa)
	HCAG_00101	Uncharacterized protein. (527 aa)
	HCAG_00784	Uncharacterized protein. (482 aa)
	HCAG_00955	UDP-glucose 4-epimerase. (286 aa)
	HCAG_01250	Endochitinase 1; Belongs to the glycosyl hydrolase 18 family. (490 aa)
	HCAG_01552	Mannose-1-phosphate guanyltransferase. (364 aa)
	HCAG_02328	Uncharacterized protein. (729 aa)
	HCAG_02857	Chitin synthase D. (1220 aa)
	HCAG_03171	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (212 aa)
	HCAG_03191	Phosphotransferase. (500 aa)
	MCR1	NADH-cytochrome b5 reductase 2; May mediate the reduction of outer membrane cytochrome b5. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (324 aa)
	HCAG_03661	Phosphotransferase. (460 aa)
	CBR1	NADH-cytochrome b5 reductase 1; Electron donor reductase for cytochrome b5. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes (By similarity). (310 aa)
	HCAG_04088	Glucosamine--fructose-6-phosphate aminotransferase. (700 aa)
	HCAG_04139	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (268 aa)
	HCAG_04323	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (492 aa)
	HCAG_04416	UDP-N-acetylglucosamine pyrophosphorylase. (515 aa)
	HCAG_04467	UTP--glucose-1-phosphate uridylyltransferase. (511 aa)
	HCAG_04742	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (390 aa)
	HCAG_06565	Endochitinase 1; Belongs to the glycosyl hydrolase 18 family. (597 aa)
	HCAG_05711	NTP_transferase domain-containing protein. (512 aa)
	HCAG_05838	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (349 aa)
	HCAG_05886	Endochitinase 1; Belongs to the glycosyl hydrolase 18 family. (493 aa)
	HCAG_05925	Glyco_hydro_20 domain-containing protein. (360 aa)
	HCAG_06001	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1701 aa)
	HCAG_06002	Uncharacterized protein. (1573 aa)
	HCAG_06040	Uncharacterized protein. (461 aa)
	HCAG_07129	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (395 aa)
	HCAG_07263	Uncharacterized protein. (801 aa)
	HCAG_08008	Chitin synthase 2. (1277 aa)
	HCAG_08145	Phosphotransferase. (615 aa)
	HCAG_08151	Uncharacterized protein. (876 aa)
	HCAG_08152	Glucosamine-6-phosphate isomerase. (294 aa)
	HCAG_08159	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (367 aa)
	HCAG_08202	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	HCAG_08436	Mannose-6-phosphate isomerase. (462 aa)
	HCAG_08808	Phosphoglucomutase; Belongs to the phosphohexose mutase family. (556 aa)
	HCAG_08824	Uncharacterized protein. (642 aa)
	HCAG_08842	Chitin synthase; Plays a major role in cell wall biogenesis. (916 aa)
	HCAG_08883	Chitin synthase; Plays a major role in cell wall biogenesis. (912 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBR1	MCR1	A6R2K7	A6R1T7	NADH-cytochrome b5 reductase 1; Electron donor reductase for cytochrome b5. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes (By similarity).	NADH-cytochrome b5 reductase 2; May mediate the reduction of outer membrane cytochrome b5. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.909
HCAG_00064	HCAG_00101	A6QRQ8	A6QRU5	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Uncharacterized protein.	0.481
HCAG_00064	HCAG_00955	A6QRQ8	A6QU99	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	UDP-glucose 4-epimerase.	0.415
HCAG_00064	HCAG_01552	A6QRQ8	A6QVZ5	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Mannose-1-phosphate guanyltransferase.	0.757
HCAG_00064	HCAG_02857	A6QRQ8	A6QZQ0	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Chitin synthase D.	0.557
HCAG_00064	HCAG_03171	A6QRQ8	A6R0L4	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.	0.986
HCAG_00064	HCAG_03191	A6QRQ8	A6R0N4	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Phosphotransferase.	0.424
HCAG_00064	HCAG_03661	A6QRQ8	A6R203	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Phosphotransferase.	0.424
HCAG_00064	HCAG_04088	A6QRQ8	A6R380	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Glucosamine--fructose-6-phosphate aminotransferase.	0.821
HCAG_00064	HCAG_04139	A6QRQ8	A6R3D1	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	0.483
HCAG_00064	HCAG_04416	A6QRQ8	A6R458	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	UDP-N-acetylglucosamine pyrophosphorylase.	0.972
HCAG_00064	HCAG_04467	A6QRQ8	A6R4A9	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	UTP--glucose-1-phosphate uridylyltransferase.	0.643
HCAG_00064	HCAG_05711	A6QRQ8	A6R9S3	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	NTP_transferase domain-containing protein.	0.713
HCAG_00064	HCAG_06001	A6QRQ8	A6RAL3	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.463
HCAG_00064	HCAG_07129	A6QRQ8	A6RBX1	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.	0.828
HCAG_00064	HCAG_08145	A6QRQ8	A6RET0	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Phosphotransferase.	0.424
HCAG_00064	HCAG_08152	A6QRQ8	A6RET7	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Glucosamine-6-phosphate isomerase.	0.655
HCAG_00064	HCAG_08159	A6QRQ8	A6REU4	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.	0.975
HCAG_00064	HCAG_08202	A6QRQ8	A6REY7	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.840
HCAG_00064	HCAG_08436	A6QRQ8	A6RFM0	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.	Mannose-6-phosphate isomerase.	0.715