node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCAG_01491 | HCAG_01606 | A6QVT4 | A6QW49 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Acetyl-coenzyme A synthetase. | 0.925 |
HCAG_01491 | HCAG_03336 | A6QVT4 | A6R129 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Branched chain alpha-keto acid dehydrogenase E1 subunit beta. | 0.998 |
HCAG_01491 | HCAG_05761 | A6QVT4 | A6R9X3 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.997 |
HCAG_01491 | HCAG_06059 | A6QVT4 | A6RAS1 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Methylmalonate-semialdehyde dehydrogenase, mitochondrial. | 0.947 |
HCAG_01491 | HCAG_07419 | A6QVT4 | A6RCR1 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Uncharacterized protein. | 0.925 |
HCAG_01491 | HCAG_07697 | A6QVT4 | A6RDI9 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.663 |
HCAG_01491 | HCAG_08375 | A6QVT4 | A6RFF9 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.812 |
HCAG_01491 | HCAG_08825 | A6QVT4 | A6RGQ8 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Dihydrolipoyl dehydrogenase. | 0.998 |
HCAG_01606 | HCAG_01491 | A6QW49 | A6QVT4 | Acetyl-coenzyme A synthetase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.925 |
HCAG_01606 | HCAG_06059 | A6QW49 | A6RAS1 | Acetyl-coenzyme A synthetase. | Methylmalonate-semialdehyde dehydrogenase, mitochondrial. | 0.915 |
HCAG_01606 | HCAG_06615 | A6QW49 | A6R8H4 | Acetyl-coenzyme A synthetase. | Probable acetate kinase. | 0.902 |
HCAG_01606 | HCAG_07419 | A6QW49 | A6RCR1 | Acetyl-coenzyme A synthetase. | Uncharacterized protein. | 0.910 |
HCAG_01606 | HCAG_07697 | A6QW49 | A6RDI9 | Acetyl-coenzyme A synthetase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.824 |
HCAG_01606 | HCAG_08039 | A6QW49 | A6REH4 | Acetyl-coenzyme A synthetase. | MaoC-like domain-containing protein. | 0.463 |
HCAG_01606 | HCAG_08058 | A6QW49 | A6REJ3 | Acetyl-coenzyme A synthetase. | Enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.427 |
HCAG_01606 | HCAG_08375 | A6QW49 | A6RFF9 | Acetyl-coenzyme A synthetase. | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.816 |
HCAG_01606 | HCAG_08621 | A6QW49 | A6RG55 | Acetyl-coenzyme A synthetase. | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.946 |
HCAG_02524 | HCAG_06059 | A6QYR7 | A6RAS1 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. | Methylmalonate-semialdehyde dehydrogenase, mitochondrial. | 0.729 |
HCAG_02524 | HCAG_08039 | A6QYR7 | A6REH4 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. | MaoC-like domain-containing protein. | 0.946 |
HCAG_02524 | HCAG_08058 | A6QYR7 | A6REJ3 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. | Enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.947 |