(11 nodes) One carbon pool by folate network (Histoplasma capsulatum NAm1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	HCAG_00541	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (712 aa)
	HCAG_02125	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (491 aa)
	HCAG_02814	Uncharacterized protein. (297 aa)
	HCAG_04224	Bifunctional purine biosynthesis protein ADE17. (626 aa)
	HCAG_04357	Formate--tetrahydrofolate ligase. (889 aa)
	HCAG_04774	Formyl_trans_N domain-containing protein. (234 aa)
	HCAG_05408	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (314 aa)
	HCAG_07107	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (619 aa)
	HCAG_07140	Uncharacterized protein. (262 aa)
	HCAG_07418	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (519 aa)
	HCAG_07999	Thymidylate synthase. (315 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00541	HCAG_02125	A6QT35	A6QXL8	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.964
HCAG_00541	HCAG_02814	A6QT35	A6QZK7	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.976
HCAG_00541	HCAG_04357	A6QT35	A6R3Z9	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Formate--tetrahydrofolate ligase.	0.959
HCAG_00541	HCAG_04774	A6QT35	A6R566	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Formyl_trans_N domain-containing protein.	0.453
HCAG_00541	HCAG_05408	A6QT35	A6R700	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.969
HCAG_00541	HCAG_07107	A6QT35	A6RBU9	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.995
HCAG_00541	HCAG_07418	A6QT35	A6RCR0	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.969
HCAG_00541	HCAG_07999	A6QT35	A6RED4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Thymidylate synthase.	0.934
HCAG_02125	HCAG_00541	A6QXL8	A6QT35	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.964
HCAG_02125	HCAG_02814	A6QXL8	A6QZK7	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Uncharacterized protein.	0.993
HCAG_02125	HCAG_04224	A6QXL8	A6R3L6	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Bifunctional purine biosynthesis protein ADE17.	0.956
HCAG_02125	HCAG_04357	A6QXL8	A6R3Z9	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Formate--tetrahydrofolate ligase.	0.962
HCAG_02125	HCAG_04774	A6QXL8	A6R566	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Formyl_trans_N domain-containing protein.	0.947
HCAG_02125	HCAG_05408	A6QXL8	A6R700	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.996
HCAG_02125	HCAG_07107	A6QXL8	A6RBU9	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.964
HCAG_02125	HCAG_07418	A6QXL8	A6RCR0	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.996
HCAG_02125	HCAG_07999	A6QXL8	A6RED4	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Thymidylate synthase.	0.958
HCAG_02814	HCAG_00541	A6QZK7	A6QT35	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.976
HCAG_02814	HCAG_02125	A6QZK7	A6QXL8	Uncharacterized protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.993
HCAG_02814	HCAG_04224	A6QZK7	A6R3L6	Uncharacterized protein.	Bifunctional purine biosynthesis protein ADE17.	0.729