STRINGSTRING
HCAG_00010 HCAG_00010 HCAG_00023 HCAG_00023 HCAG_01606 HCAG_01606 HCAG_02122 HCAG_02122 HCAG_03111 HCAG_03111 HCAG_03322 HCAG_03322 HCAG_04675 HCAG_04675 HCAG_05408 HCAG_05408 HCAG_05409 HCAG_05409 HCAG_06615 HCAG_06615 HCAG_06845 HCAG_06845 HCAG_06856 HCAG_06856 HCAG_06162 HCAG_06162 HCAG_07206 HCAG_07206 HCAG_07418 HCAG_07418 HCAG_07552 HCAG_07552 HCAG_09020 HCAG_09020
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCAG_00010Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (273 aa)
HCAG_00023GMC_OxRdtase_N domain-containing protein; Belongs to the GMC oxidoreductase family. (438 aa)
HCAG_01606Acetyl-coenzyme A synthetase. (669 aa)
HCAG_02122Uncharacterized protein. (276 aa)
HCAG_03111D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (488 aa)
HCAG_03322Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (354 aa)
HCAG_04675S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (286 aa)
HCAG_05408Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (314 aa)
HCAG_054092,3-bisphosphoglycerate-independent phosphoglycerate mutase. (541 aa)
HCAG_06615Probable acetate kinase. (428 aa)
HCAG_06845Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (385 aa)
HCAG_06856Uncharacterized protein. (434 aa)
HCAG_06162Aminotran_5 domain-containing protein. (327 aa)
HCAG_07206S-(Hydroxymethyl)glutathione dehydrogenase. (388 aa)
HCAG_07418Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (519 aa)
HCAG_07552ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (794 aa)
HCAG_09020D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (603 aa)
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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