(16 nodes) Porphyrin and chlorophyll metabolism network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_01224	Uncharacterized protein; Belongs to the precorrin methyltransferase family. (498 aa)
	HCAG_01404	Coproporphyrinogen III oxidase. (354 aa)
	HCAG_01919	GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (670 aa)
	HCAG_01937	5-aminolevulinate synthase, mitochondrial. (652 aa)
	HCAG_02020	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (364 aa)
	HCAG_02662	Porphobilinogen deaminase. (345 aa)
	HCAG_02951	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (296 aa)
	HCAG_03974	Uncharacterized protein. (260 aa)
	HCAG_05249	Uncharacterized protein. (267 aa)
	HCAG_05597	Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (238 aa)
	HCAG_06432	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (504 aa)
	HCAG_05715	Cytochrome c oxidase assembly protein COX15. (492 aa)
	HCAG_05923	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (595 aa)
	HCAG_06107	Uncharacterized protein. (228 aa)
	HCAG_06303	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
	HCAG_07691	Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (348 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01224	HCAG_01404	A6QV17	A6QVJ7	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	Coproporphyrinogen III oxidase.	0.547
HCAG_01224	HCAG_02020	A6QV17	A6QXB3	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.852
HCAG_01224	HCAG_02662	A6QV17	A6QZ55	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	Porphobilinogen deaminase.	0.993
HCAG_01224	HCAG_02951	A6QV17	A6QZZ4	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.647
HCAG_01224	HCAG_03974	A6QV17	A6R2W6	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	Uncharacterized protein.	0.998
HCAG_01224	HCAG_05249	A6QV17	A6R6J1	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	Uncharacterized protein.	0.987
HCAG_01224	HCAG_05923	A6QV17	A6RAD5	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.596
HCAG_01404	HCAG_01224	A6QVJ7	A6QV17	Coproporphyrinogen III oxidase.	Uncharacterized protein; Belongs to the precorrin methyltransferase family.	0.547
HCAG_01404	HCAG_01919	A6QVJ7	A6QX12	Coproporphyrinogen III oxidase.	GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.439
HCAG_01404	HCAG_01937	A6QVJ7	A6QX30	Coproporphyrinogen III oxidase.	5-aminolevulinate synthase, mitochondrial.	0.613
HCAG_01404	HCAG_02020	A6QVJ7	A6QXB3	Coproporphyrinogen III oxidase.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.672
HCAG_01404	HCAG_02662	A6QVJ7	A6QZ55	Coproporphyrinogen III oxidase.	Porphobilinogen deaminase.	0.695
HCAG_01404	HCAG_02951	A6QVJ7	A6QZZ4	Coproporphyrinogen III oxidase.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.648
HCAG_01404	HCAG_05249	A6QVJ7	A6R6J1	Coproporphyrinogen III oxidase.	Uncharacterized protein.	0.648
HCAG_01404	HCAG_05715	A6QVJ7	A6R9S7	Coproporphyrinogen III oxidase.	Cytochrome c oxidase assembly protein COX15.	0.652
HCAG_01404	HCAG_05923	A6QVJ7	A6RAD5	Coproporphyrinogen III oxidase.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.987
HCAG_01404	HCAG_06432	A6QVJ7	A6R7Z1	Coproporphyrinogen III oxidase.	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.433
HCAG_01919	HCAG_01404	A6QX12	A6QVJ7	GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Coproporphyrinogen III oxidase.	0.439
HCAG_01919	HCAG_02020	A6QX12	A6QXB3	GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.511
HCAG_01919	HCAG_02662	A6QX12	A6QZ55	GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Porphobilinogen deaminase.	0.474