STRINGSTRING
HCAG_00010 HCAG_00010 HCAG_00014 HCAG_00014 HCAG_00035 HCAG_00035 HCAG_00104 HCAG_00104 HCAG_00290 HCAG_00290 HCAG_00386 HCAG_00386 HCAG_00397 HCAG_00397 HCAG_00638 HCAG_00638 HCAG_00748 HCAG_00748 HCAG_00793 HCAG_00793 HCAG_01145 HCAG_01145 HCAG_01437 HCAG_01437 HCAG_01497 HCAG_01497 HCAG_01575 HCAG_01575 HCAG_01667 HCAG_01667 HCAG_02035 HCAG_02035 HCAG_02122 HCAG_02122 HCAG_02124 HCAG_02124 HCAG_02260 HCAG_02260 HCAG_02357 HCAG_02357 HCAG_02710 HCAG_02710 HCAG_02799 HCAG_02799 HCAG_02997 HCAG_02997 HCAG_03050 HCAG_03050 HCAG_03101 HCAG_03101 HCAG_03111 HCAG_03111 HCAG_03270 HCAG_03270 HCAG_03302 HCAG_03302 HCAG_03385 HCAG_03385 HCAG_03428 HCAG_03428 HCAG_03447 HCAG_03447 HCAG_03540 HCAG_03540 HCAG_03751 HCAG_03751 HCAG_03801 HCAG_03801 HCAG_03900 HCAG_03900 HCAG_03976 HCAG_03976 HCAG_04000 HCAG_04000 HCAG_04093 HCAG_04093 HCAG_04183 HCAG_04183 HCAG_04227 HCAG_04227 HCAG_04242 HCAG_04242 HCAG_04358 HCAG_04358 HCAG_04514 HCAG_04514 HCAG_04577 HCAG_04577 HCAG_04617 HCAG_04617 HCAG_04910 HCAG_04910 HCAG_04939 HCAG_04939 HCAG_05000 HCAG_05000 HCAG_05070 HCAG_05070 HCAG_05090 HCAG_05090 HCAG_05224 HCAG_05224 HCAG_05266 HCAG_05266 HCAG_05408 HCAG_05408 HCAG_05409 HCAG_05409 HCAG_05546 HCAG_05546 HCAG_05565 HCAG_05565 HCAG_05584 HCAG_05584 HCAG_05587 HCAG_05587 HCAG_06360 HCAG_06360 HCAG_06683 HCAG_06683 HCAG_06699 HCAG_06699 HCAG_06729 HCAG_06729 HCAG_06816 HCAG_06816 HCAG_06854 HCAG_06854 HCAG_06856 HCAG_06856 HCAG_06981 HCAG_06981 HCAG_07004 HCAG_07004 HCAG_05679 HCAG_05679 HCAG_05953 HCAG_05953 HCAG_06098 HCAG_06098 HCAG_06102 HCAG_06102 HCAG_06194 HCAG_06194 HCAG_06253 HCAG_06253 HCAG_07028 HCAG_07028 HCAG_07104 HCAG_07104 ARG2 ARG2 HCAG_07205 HCAG_07205 HCAG_07418 HCAG_07418 HCAG_07434 HCAG_07434 HCAG_07435 HCAG_07435 HCAG_07464 HCAG_07464 HCAG_07552 HCAG_07552 HCAG_07634 HCAG_07634 HCAG_07781 HCAG_07781 HCAG_07785 HCAG_07785 HCAG_07805 HCAG_07805 HCAG_08023 HCAG_08023 HCAG_08029 HCAG_08029 HCAG_08076 HCAG_08076 HCAG_08116 HCAG_08116 HCAG_08275 HCAG_08275 HCAG_08470 HCAG_08470 HCAG_08550 HCAG_08550 HCAG_08678 HCAG_08678 HCAG_08889 HCAG_08889 HCAG_08890 HCAG_08890 HCAG_08945 HCAG_08945 HCAG_09020 HCAG_09020 HCAG_09107 HCAG_09107
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCAG_00010Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (273 aa)
HCAG_00014Homoserine dehydrogenase. (370 aa)
HCAG_00035Arginase; Belongs to the arginase family. (332 aa)
HCAG_00104Acetolactate synthase. (610 aa)
HCAG_00290Chorismate mutase. (269 aa)
HCAG_00386Cysteine synthase. (377 aa)
HCAG_00397RmlD_sub_bind domain-containing protein. (332 aa)
HCAG_00638Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
HCAG_00748Anthranilate synthase component II. (652 aa)
HCAG_00793Threonine synthase. (536 aa)
HCAG_01145Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (376 aa)
HCAG_01437Homoserine O-acetyltransferase. (511 aa)
HCAG_01497Uncharacterized protein. (454 aa)
HCAG_01575Saccharopine dehydrogenase. (457 aa)
HCAG_01667Ribose-phosphate pyrophosphokinase 3. (297 aa)
HCAG_02035Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (549 aa)
HCAG_02122Uncharacterized protein. (276 aa)
HCAG_02124Semialdhyde_dh domain-containing protein. (338 aa)
HCAG_022603-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
HCAG_02357Histidinol dehydrogenase. (1148 aa)
HCAG_02710Cystathionine gamma-lyase. (457 aa)
HCAG_02799Cysteine synthase 2. (409 aa)
HCAG_02997Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (471 aa)
HCAG_03050Uncharacterized protein. (344 aa)
HCAG_03101Aspartokinase. (518 aa)
HCAG_03111D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (488 aa)
HCAG_03270Phospho-2-dehydro-3-deoxyheptonate aldolase. (374 aa)
HCAG_03302Uncharacterized protein. (378 aa)
HCAG_03385Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (418 aa)
HCAG_03428S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
HCAG_03447Glutamine amidotransferase type-2 domain-containing protein. (747 aa)
HCAG_03540Cystathionine gamma-synthase. (606 aa)
HCAG_03751Aspartate aminotransferase. (443 aa)
HCAG_03801Acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (479 aa)
HCAG_03900Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (332 aa)
HCAG_03976Ribose-phosphate pyrophosphokinase. (381 aa)
HCAG_04000Dihydroxy-acid dehydratase. (611 aa)
HCAG_04093Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (343 aa)
HCAG_04183M20_dimer domain-containing protein. (518 aa)
HCAG_04227Uncharacterized protein. (1287 aa)
HCAG_04242PALP domain-containing protein. (431 aa)
HCAG_04358Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (363 aa)
HCAG_04514Beta_elim_lyase domain-containing protein. (393 aa)
HCAG_04577Dihydroxy-acid dehydratase. (499 aa)
HCAG_04617Amino transferase. (532 aa)
HCAG_04910Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
HCAG_04939Uncharacterized protein. (292 aa)
HCAG_05000Transketolase 1. (650 aa)
HCAG_05070Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (497 aa)
HCAG_05090Citrate synthase; Belongs to the citrate synthase family. (470 aa)
HCAG_05224Anthranilate synthase component I. (511 aa)
HCAG_05266Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (763 aa)
HCAG_05408Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (314 aa)
HCAG_054092,3-bisphosphoglycerate-independent phosphoglycerate mutase. (541 aa)
HCAG_05546Chorismate synthase. (407 aa)
HCAG_055655-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. (763 aa)
HCAG_05584Mitochondrial acetolactate synthase small subunit. (336 aa)
HCAG_05587Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (346 aa)
HCAG_06360ATP phosphoribosyltransferase. (324 aa)
HCAG_06683Uncharacterized protein. (410 aa)
HCAG_066993-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1538 aa)
HCAG_06729Histidinol-phosphate aminotransferase. (321 aa)
HCAG_06816Ribose-phosphate pyrophosphokinase I. (456 aa)
HCAG_06854Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (797 aa)
HCAG_06856Uncharacterized protein. (434 aa)
HCAG_06981Citrate synthase; Belongs to the citrate synthase family. (473 aa)
HCAG_07004O-acetylhomoserine. (441 aa)
HCAG_05679Aminotran_1_2 domain-containing protein. (495 aa)
HCAG_05953Tryptophan synthase. (600 aa)
HCAG_06098Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (417 aa)
HCAG_06102Aspartate aminotransferase. (429 aa)
HCAG_06194Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (450 aa)
HCAG_06253Threonine dehydratase. (540 aa)
HCAG_07028Gln_synt_b-grasp domain-containing protein; Belongs to the glutamine synthetase family. (210 aa)
HCAG_071043-isopropylmalate dehydratase. (714 aa)
ARG2Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (684 aa)
HCAG_07205Beta_elim_lyase domain-containing protein. (418 aa)
HCAG_07418Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (519 aa)
HCAG_07434Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (498 aa)
HCAG_07435Glutamate 5-kinase. (507 aa)
HCAG_07464Gamma-glutamyl phosphate reductase. (365 aa)
HCAG_07552ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (794 aa)
HCAG_076343-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (374 aa)
HCAG_07781Pyruvate kinase; Belongs to the pyruvate kinase family. (542 aa)
HCAG_07785Homoisocitrate dehydrogenase, mitochondrial. (363 aa)
HCAG_07805Argininosuccinate lyase. (471 aa)
HCAG_08023Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (278 aa)
HCAG_08029Cystathionine beta-lyase. (447 aa)
HCAG_08076Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (396 aa)
HCAG_08116Phospho-2-dehydro-3-deoxyheptonate aldolase. (383 aa)
HCAG_08275Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa)
HCAG_08470Threonine aldolase. (374 aa)
HCAG_085501-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (243 aa)
HCAG_08678Aspartate aminotransferase. (419 aa)
HCAG_08889PALP domain-containing protein. (411 aa)
HCAG_08890Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (433 aa)
HCAG_08945Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (339 aa)
HCAG_09020D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (603 aa)
HCAG_09107L-aminoadipate-semialdehyde dehydrogenase large subunit. (1179 aa)
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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