(44 nodes) S-adenosyl-L-methionine-dependent methyltransferase superfamily network (Komagataeibacter europaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	yfiC	tRNA1(Val) (adenine(37)-N6)-methyltransferase. (251 aa)
	pcm	protein-L-isoaspartate O-methyltransferase. (228 aa)
	ubiE	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (265 aa)
	ubiG1	Ubiquinone biosynthesis O-methyltransferase. (424 aa)
	dpnA1	Modification methylase DpnIIB; Belongs to the N(4)/N(6)-methyltransferase family. (362 aa)
	fokIM	Modification methylase FokI. (426 aa)
	cfa	Cyclopropane-fatty-acyl-phospholipid synthase. (415 aa)
	rsmA	Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (283 aa)
	KOEU_03610	Methyltransferase domain protein. (250 aa)
	cheR	Chemotaxis protein methyltransferase. (456 aa)
	rlmM	Ribosomal RNA large subunit methyltransferase M. (316 aa)
	KOEU_04530	Hypothetical protein. (210 aa)
	bcgIA	Restriction enzyme BgcI subunit alpha. (554 aa)
	BioC	Biotin biosynthesis protein BioC. (285 aa)
	ubiG2	Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (255 aa)
	prmC1	Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (287 aa)
	bioD1	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (470 aa)
	rlmE	Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (254 aa)
	tlyA	16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA. (247 aa)
	cobL	precorrin-6Y C(5,15)-methyltransferase. (416 aa)
	rsmD	Ribosomal RNA small subunit methyltransferase D. (191 aa)
	rsmG	Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (202 aa)
	trmB	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (234 aa)
	tpm	Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. (264 aa)
	KOEU_37320	Type I restriction enzyme EcoKI subunit R. (1492 aa)
	PmtA	Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase. (237 aa)
	yhdJ	DNA adenine methyltransferase YhdJ; Belongs to the N(4)/N(6)-methyltransferase family. (296 aa)
	prmA	Ribosomal protein L11 methyltransferase. (300 aa)
	rlmD	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (420 aa)
	MetX	Hypothetical protein. (203 aa)
	KOEU_20090	Putative methyltransferase. (439 aa)
	rsmB1	Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (444 aa)
	dpnA2	Modification methylase DpnIIB; Belongs to the N(4)/N(6)-methyltransferase family. (247 aa)
	KOEU_25150	Hypothetical protein. (450 aa)
	KOEU_25560	Hypothetical protein. (338 aa)
	rsmH	Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (333 aa)
	KOEU_27890	Hypothetical protein. (214 aa)
	speE	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (286 aa)
	rsmB2	Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (431 aa)
	KOEU_35740	Hypothetical protein; SNF2 family N-terminal domain. (1699 aa)
	dpnA3	Modification methylase DpnIIB. (1012 aa)
	rlmJ	Ribosomal RNA large subunit methyltransferase J; Specifically methylates the adenine in position 2030 of 23S rRNA. (283 aa)
	dcm	DNA-cytosine methyltransferase. (434 aa)
	prmC2	Release factor glutamine methyltransferase; Belongs to the methyltransferase superfamily. (302 aa)

Your Current Organism:

Komagataeibacter europaeus

NCBI taxonomy Id: 33995
Other names: ATCC 51845, Acetobacter europaeus, DSM 6160, Gluconacetobacter europaeus, K. europaeus, LMG 18890, LMG:18890, strain DES 11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BioC	KOEU_25560	KOEU_06210	KOEU_25560	Biotin biosynthesis protein BioC.	Hypothetical protein.	0.759
BioC	bioD1	KOEU_06210	KOEU_06410	Biotin biosynthesis protein BioC.	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.462
KOEU_03610	bioD1	KOEU_03610	KOEU_06410	Methyltransferase domain protein.	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.418
KOEU_03610	yfiC	KOEU_03610	KOEU_28910	Methyltransferase domain protein.	tRNA1(Val) (adenine(37)-N6)-methyltransferase.	0.441
KOEU_25560	BioC	KOEU_25560	KOEU_06210	Hypothetical protein.	Biotin biosynthesis protein BioC.	0.759
KOEU_25560	KOEU_27890	KOEU_25560	KOEU_27890	Hypothetical protein.	Hypothetical protein.	0.823
KOEU_27890	KOEU_25560	KOEU_27890	KOEU_25560	Hypothetical protein.	Hypothetical protein.	0.823
KOEU_35740	dcm	KOEU_35740	KOEU_33980	Hypothetical protein; SNF2 family N-terminal domain.	DNA-cytosine methyltransferase.	0.568
MetX	bioD1	KOEU_17360	KOEU_06410	Hypothetical protein.	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.418
PmtA	bioD1	KOEU_13500	KOEU_06410	Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase.	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.462
bioD1	BioC	KOEU_06410	KOEU_06210	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Biotin biosynthesis protein BioC.	0.462
bioD1	KOEU_03610	KOEU_06410	KOEU_03610	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Methyltransferase domain protein.	0.418
bioD1	MetX	KOEU_06410	KOEU_17360	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Hypothetical protein.	0.418
bioD1	PmtA	KOEU_06410	KOEU_13500	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase.	0.462
bioD1	ubiE	KOEU_06410	KOEU_00530	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).	0.462
bioD1	ubiG1	KOEU_06410	KOEU_00920	ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Ubiquinone biosynthesis O-methyltransferase.	0.462
dcm	KOEU_35740	KOEU_33980	KOEU_35740	DNA-cytosine methyltransferase.	Hypothetical protein; SNF2 family N-terminal domain.	0.568
dpnA1	fokIM	KOEU_03090	KOEU_03100	Modification methylase DpnIIB; Belongs to the N(4)/N(6)-methyltransferase family.	Modification methylase FokI.	0.704
dpnA2	yhdJ	KOEU_24730	KOEU_13720	Modification methylase DpnIIB; Belongs to the N(4)/N(6)-methyltransferase family.	DNA adenine methyltransferase YhdJ; Belongs to the N(4)/N(6)-methyltransferase family.	0.762
fokIM	dpnA1	KOEU_03100	KOEU_03090	Modification methylase FokI.	Modification methylase DpnIIB; Belongs to the N(4)/N(6)-methyltransferase family.	0.704

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