STRINGSTRING
ABY95703.1 ABY95703.1 ABY95777.1 ABY95777.1 ABY95823.1 ABY95823.1 ABY95902.1 ABY95902.1 ABY95609.1 ABY95609.1 galK galK ABY94264.1 ABY94264.1 ABY94242.1 ABY94242.1 hprK hprK ABY94209.1 ABY94209.1 ABY94208.1 ABY94208.1 ABY94207.1 ABY94207.1 glpK glpK ABY94162.1 ABY94162.1 pfp pfp ABY94121.1 ABY94121.1 mcsB mcsB ABY94003.1 ABY94003.1 ABY94002.1 ABY94002.1 ABY94001.1 ABY94001.1 ABY94000.1 ABY94000.1 coaX coaX ABY93971.1 ABY93971.1 ABY93944.1 ABY93944.1 ispE ispE ABY93838.1 ABY93838.1 ABY93826.1 ABY93826.1 ABY93825.1 ABY93825.1 ABY93824.1 ABY93824.1 thrB thrB ABY94296.1 ABY94296.1 ABY94330.1 ABY94330.1 pfkA pfkA ABY94347.1 ABY94347.1 ABY94449.1 ABY94449.1 ABY94483.1 ABY94483.1 aroK aroK nadK nadK spoIIAB spoIIAB ABY94859.1 ABY94859.1 ABY94886.1 ABY94886.1 ABY94960.1 ABY94960.1 ABY94967.1 ABY94967.1 ABY95011.1 ABY95011.1 ABY95082.1 ABY95082.1 coaE coaE ABY95183.1 ABY95183.1 ABY95199.1 ABY95199.1 ABY95200.1 ABY95200.1 ABY95264.1 ABY95264.1 thiM thiM ABY95335.1 ABY95335.1 ABY95336.1 ABY95336.1 ABY95338.1 ABY95338.1 ABY95339.1 ABY95339.1 ABY95371.1 ABY95371.1 ABY95432.1 ABY95432.1 ABY95459.1 ABY95459.1 ABY95528.1 ABY95528.1 ABY95572.1 ABY95572.1 ABY95573.1 ABY95573.1 ABY95577.1 ABY95577.1 ABY95579.1 ABY95579.1 ABY95599.1 ABY95599.1 ABY95607.1 ABY95607.1 rbsK rbsK xylB xylB ABY95691.1 ABY95691.1 ABY95693.1 ABY95693.1 ABY93735.1 ABY93735.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABY95703.1Response regulator receiver protein; PFAM: phosphotransferase system, lactose/cellobiose-specific IIB subunit. (108 aa)
ABY95777.1TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein. (315 aa)
ABY95823.1TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; metal-dependent phosphohydrolase, HD sub domain; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; HDOD; SMART: PAS domain containing protein; metal-dependent phosphohydrolase, HD region. (632 aa)
ABY95902.1PFAM: diacylglycerol kinase, catalytic region. (290 aa)
ABY95609.1Transcriptional antiterminator, BglG; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; M trans-acting positive regulator; PRD domain protein; Helix-turn-helix, type 11 domain protein. (705 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (387 aa)
ABY94264.1PFAM: carbohydrate kinase, FGGY; Belongs to the FGGY kinase family. (506 aa)
ABY94242.1TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein; ATPase, BadF/BadG/BcrA/BcrD type. (312 aa)
hprKHPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] (305 aa)
ABY94209.1TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; PFAM: PTS system fructose subfamily IIA component. (130 aa)
ABY94208.1TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase. (212 aa)
ABY94207.1TIGRFAM: dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase. (332 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (497 aa)
ABY94162.1PFAM: Osmosensitive K+ channel His kinase sensor; UspA domain protein. (379 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (414 aa)
ABY94121.1Osmosensitive K+ channel histidine kinase-like protein. (137 aa)
mcsBATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins. (339 aa)
ABY94003.1TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS, fructose-specific IIB subunit. (103 aa)
ABY94002.1TIGRFAM: PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system, EIIC. (348 aa)
ABY94001.1Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. (149 aa)
ABY94000.1Transcriptional antiterminator, BglG; PFAM: regulatory protein, DeoR; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; M trans-acting positive regulator; PRD domain protein; Helix-turn-helix, type 11 domain protein. (652 aa)
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (255 aa)
ABY93971.1PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein. (460 aa)
ABY93944.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein. (451 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa)
ABY93838.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein. (470 aa)
ABY93826.1TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit. (452 aa)
ABY93825.1Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. (148 aa)
ABY93824.11-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa)
ABY94296.1PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (322 aa)
ABY94330.1Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (324 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)
ABY94347.1Pyruvate kinase., Pyruvate, water dikinase; PFAM: pyruvate kinase; PEP-utilising enzyme, mobile region; Belongs to the pyruvate kinase family. (583 aa)
ABY94449.1PFAM: ATP-NAD/AcoX kinase. (332 aa)
ABY94483.1Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (456 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (171 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (283 aa)
spoIIABPutative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (143 aa)
ABY94859.1TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. (316 aa)
ABY94886.1CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; P2 response regulator binding domain protein. (660 aa)
ABY94960.1PFAM: Dak phosphatase. (533 aa)
ABY94967.1PFAM: protein kinase; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase. (625 aa)
ABY95011.1Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (270 aa)
ABY95082.1Hypothetical protein. (71 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)
ABY95183.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein. (446 aa)
ABY95199.1TIGRFAM: capsular exopolysaccharide family. (235 aa)
ABY95200.1PFAM: lipopolysaccharide biosynthesis protein. (239 aa)
ABY95264.1PFAM: lipopolysaccharide biosynthesis protein. (315 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (264 aa)
ABY95335.1PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (438 aa)
ABY95336.1PFAM: phosphotransferase system, lactose/cellobiose-specific IIB subunit. (108 aa)
ABY95338.1Hypothetical protein. (154 aa)
ABY95339.1Transcriptional antiterminator, BglG; PFAM: phosphotransferase system, lactose/cellobiose-specific IIB subunit; PRD domain protein; Helix-turn-helix, type 11 domain protein. (523 aa)
ABY95371.1Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region, ATPase domain protein domain protein. (287 aa)
ABY95432.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein. (466 aa)
ABY95459.1TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC. (466 aa)
ABY95528.1Adenosylcobinamide kinase; PFAM: cobalbumin biosynthesis enzyme. (184 aa)
ABY95572.1Transcriptional antiterminator, BglG; PFAM: phosphotransferase system, lactose/cellobiose-specific IIB subunit; PRD domain protein; Helix-turn-helix, type 11 domain protein. (680 aa)
ABY95573.1TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system, EIIC; phosphotransferase system, lactose/cellobiose-specific IIB subunit. (478 aa)
ABY95577.1PFAM: phosphotransferase system, lactose/cellobiose-specific IIB subunit. (103 aa)
ABY95579.1PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (420 aa)
ABY95599.1PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (316 aa)
ABY95607.1PFAM: phosphotransferase system, lactose/cellobiose-specific IIB subunit. (99 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
xylBTIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY. (500 aa)
ABY95691.1PFAM: PTS system sorbose subfamily IIB component. (166 aa)
ABY95693.1PFAM: phosphotransferase system PTS, sorbose-specific IIC subunit. (259 aa)
ABY93735.1Hypothetical protein. (193 aa)
Your Current Organism:
Thermoanaerobacter pseudethanolicus
NCBI taxonomy Id: 340099
Other names: Clostridium thermohydrosulfuricum 39E, T. pseudethanolicus ATCC 33223, Thermoanaerobacter ethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus 39E, Thermoanaerobacter pseudethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus str. ATCC 33223, Thermoanaerobacter pseudethanolicus strain ATCC 33223
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