STRINGSTRING
ABY95075.1 ABY95075.1 hutH hutH pdxT pdxT ABY95314.1 ABY95314.1 ABY95315.1 ABY95315.1 arcA arcA ABY95387.1 ABY95387.1 ABY95450.1 ABY95450.1 ABY95464.1 ABY95464.1 hutI hutI ABY95472.1 ABY95472.1 hutU hutU ABY95591.1 ABY95591.1 ABY95600.1 ABY95600.1 gcvT gcvT gcvH gcvH gcvPA gcvPA gcvPB gcvPB ABY95629.1 ABY95629.1 ABY95638.1 ABY95638.1 rbsD rbsD rbsK rbsK ABY95674.1 ABY95674.1 ABY95687.1 ABY95687.1 ABY95700.1 ABY95700.1 ABY95701.1 ABY95701.1 ABY95722.1 ABY95722.1 arcA-2 arcA-2 ABY93864.1 ABY93864.1 ABY93890.1 ABY93890.1 tdh tdh ABY94133.1 ABY94133.1 ABY94169.1 ABY94169.1 glpK glpK ABY94209.1 ABY94209.1 ABY94216.1 ABY94216.1 ABY94253.1 ABY94253.1 ABY94254.1 ABY94254.1 ABY94262.1 ABY94262.1 gpmI gpmI deoD deoD ABY94501.1 ABY94501.1 ABY94502.1 ABY94502.1 ABY94521.1 ABY94521.1 ABY94532.1 ABY94532.1 ABY94534.1 ABY94534.1 ABY94559.1 ABY94559.1 ABY94630.1 ABY94630.1 ABY94632.1 ABY94632.1 nagB nagB dtd dtd ABY94806.1 ABY94806.1 ABY94818.1 ABY94818.1 ABY94965.1 ABY94965.1 ABY94976.1 ABY94976.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABY95075.1PFAM: NAD/NADP octopine/nopaline dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein. (366 aa)
hutHTIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase. (508 aa)
pdxTSNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (189 aa)
ABY95314.1PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein. (386 aa)
ABY95315.1PFAM: SAF domain. (100 aa)
arcAArginine deiminase; PFAM: amidinotransferase. (408 aa)
ABY95387.1PFAM: amidohydrolase; Amidohydrolase 3. (383 aa)
ABY95450.1Hypothetical protein. (226 aa)
ABY95464.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (135 aa)
hutITIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (415 aa)
ABY95472.1TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase-like. (298 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (549 aa)
ABY95591.1TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type. (320 aa)
ABY95600.15-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase. (253 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvPAGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (447 aa)
gcvPBGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (484 aa)
ABY95629.1TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: histidine triad (HIT) protein; galactose-1-phosphate uridyl transferase domain protein. (323 aa)
ABY95638.15-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase. (242 aa)
rbsDRbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (130 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
ABY95674.1PFAM: oxidoreductase domain protein. (250 aa)
ABY95687.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa)
ABY95700.1PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein. (389 aa)
ABY95701.1PFAM: SAF domain. (96 aa)
ABY95722.1TIGRFAM: alanine dehydrogenase; PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; alanine dehydrogenase/PNT domain protein. (374 aa)
arcA-2Arginine deiminase; PFAM: amidinotransferase. (407 aa)
ABY93864.1Zn-dependent hydrolase of the beta-lactamase fold-like protein. (214 aa)
ABY93890.1PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (353 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (348 aa)
ABY94133.1PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding. (249 aa)
ABY94169.1PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain. (378 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (497 aa)
ABY94209.1TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; PFAM: PTS system fructose subfamily IIA component. (130 aa)
ABY94216.1TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type. (327 aa)
ABY94253.1PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain. (362 aa)
ABY94254.1PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain. (349 aa)
ABY94262.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
deoDTIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase, family 1. (233 aa)
ABY94501.1PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component. (416 aa)
ABY94502.1TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; 2-hydroxyglutaryl-CoA dehydratase, D-component. (539 aa)
ABY94521.1PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein. (169 aa)
ABY94532.1PFAM: class II aldolase/adducin family protein. (213 aa)
ABY94534.1PFAM: Alcohol dehydrogenase GroES domain protein. (318 aa)
ABY94559.1PFAM: cobalamin B12-binding domain protein. (137 aa)
ABY94630.1TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding. (298 aa)
ABY94632.1PFAM: cyclase family protein. (205 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (253 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa)
ABY94806.1PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding. (274 aa)
ABY94818.1HI0933 family protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; FAD dependent oxidoreductase. (406 aa)
ABY94965.1PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa)
ABY94976.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa)
Your Current Organism:
Thermoanaerobacter pseudethanolicus
NCBI taxonomy Id: 340099
Other names: Clostridium thermohydrosulfuricum 39E, T. pseudethanolicus ATCC 33223, Thermoanaerobacter ethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus 39E, Thermoanaerobacter pseudethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus str. ATCC 33223, Thermoanaerobacter pseudethanolicus strain ATCC 33223
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