STRINGSTRING
eno eno Pars_0063 Pars_0063 Pars_0138 Pars_0138 Pars_0139 Pars_0139 fbp fbp Pars_0189 Pars_0189 Pars_0193 Pars_0193 Pars_0194 Pars_0194 Pars_0195 Pars_0195 Pars_0196 Pars_0196 Pars_0396 Pars_0396 Pars_0510 Pars_0510 Pars_0511 Pars_0511 Pars_0515 Pars_0515 Pars_0547 Pars_0547 Pars_0554 Pars_0554 tpiA tpiA gap gap pgk pgk acsA acsA Pars_1008 Pars_1008 Pars_1187 Pars_1187 Pars_1188 Pars_1188 Pars_1189 Pars_1189 Pars_1249 Pars_1249 Pars_1250 Pars_1250 Pars_1308 Pars_1308 Pars_1445 Pars_1445 apgM apgM Pars_1705 Pars_1705 Pars_1706 Pars_1706 Pars_1707 Pars_1707 Pars_1708 Pars_1708 Pars_1804 Pars_1804 Pars_1805 Pars_1805 Pars_1872 Pars_1872 Pars_2130 Pars_2130 Pars_2277 Pars_2277 Pars_2278 Pars_2278 Pars_2279 Pars_2279
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (419 aa)
Pars_0063PFAM: pyruvate kinase; KEGG: pai:PAE0819 pyruvate kinase; Belongs to the pyruvate kinase family. (449 aa)
Pars_0138TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pis:Pisl_1174 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit. (314 aa)
Pars_0139PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE0939 2-oxoacid ferredoxin oxidoreductase alpha subunit. (633 aa)
fbpFructose-bisphosphate aldolase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (406 aa)
Pars_0189PFAM: Aldehyde ferredoxin oxidoreductase-like; KEGG: pai:PAE1029 aldehyde ferredoxin oxidoreductase (aor). (616 aa)
Pars_0193KEGG: pai:PAE1040 pyruvate ferredoxin oxidoreductase gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase. (175 aa)
Pars_0194TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pis:Pisl_1231 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit. (102 aa)
Pars_0195Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE1042 pyruvate ferredoxin oxidoreductase alpha subunit. (393 aa)
Pars_0196Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE1043 pyruvate ferredoxin oxidoreductase beta subunit. (314 aa)
Pars_0396Succinate semialdehyde reductase (NADPH); PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pai:PAE2931 alcohol dehydrogenase (Zinc). (352 aa)
Pars_0510Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; KEGG: pis:Pisl_1888 phosphoenolpyruvate synthase. (334 aa)
Pars_0511PFAM: PEP-utilising enzyme, mobile region; KEGG: gme:Gmet_2100 hypothetical protein. (594 aa)
Pars_0515PFAM: PEP-utilising enzyme, mobile region; KEGG: rxy:Rxyl_1575 PEP-utilising enzyme, mobile region. (546 aa)
Pars_0547PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sso:SSO1220 alcohol dehydrogenase (Zn containing). (361 aa)
Pars_0554Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; PFAM: aldehyde dehydrogenase; acyl-CoA reductase; KEGG: sto:ST2477 hypothetical NADP-dependent glyceraldehyde-3-phosphate dehydrogenase. (476 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (224 aa)
gapKEGG: pai:PAE1740 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase. (344 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: pai:PAE1742 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (411 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (670 aa)
Pars_1008KEGG: pai:PAE3383 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region. (916 aa)
Pars_1187PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: pai:PAE2648 pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). (408 aa)
Pars_1188PFAM: Transketolase, central region; Transketolase domain protein; KEGG: pai:PAE2646 pyruvate dehydrogenase E1 beta subunit. (322 aa)
Pars_1189PFAM: dehydrogenase, E1 component; KEGG: pai:PAE2644 pyruvate dehydrogenase E1 alpha subunit. (370 aa)
Pars_1249TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE1558 2-oxoacid ferredoxin oxidoreductase beta subunit. (298 aa)
Pars_1250PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE1559 2-oxoacid ferredoxin oxidoreductase alpha subunit. (546 aa)
Pars_1308PFAM: AMP-dependent synthetase and ligase; KEGG: pis:Pisl_0218 AMP-dependent synthetase and ligase. (633 aa)
Pars_1445Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (812 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (411 aa)
Pars_1705PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE3274 2-ketoacid ferredoxin oxidoreductase beta subunit. (299 aa)
Pars_1706PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE3275 2-ketoacid ferredoxin oxidoreductase alpha subunit. (384 aa)
Pars_1707TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE3276 2-ketoacid ferredoxin oxidoreductase delta subunit. (82 aa)
Pars_1708TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pai:PAE3279 2-ketoacid ferredoxin oxidoreductase gamma subunit. (182 aa)
Pars_1804PFAM: CoA-binding domain protein; KEGG: pai:PAE3250 hypothetical protein. (461 aa)
Pars_1805KEGG: pai:PAE3249 hypothetical protein. (233 aa)
Pars_1872Glucokinase; PFAM: ROK family protein; KEGG: pai:PAE3437 glucokinase (ROK family protein), conjectural. (296 aa)
Pars_2130TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: sugar isomerase (SIS); KEGG: pai:PAE1610 hypothetical protein. (300 aa)
Pars_2277PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pis:Pisl_0326 thiamine pyrophosphate enzyme domain protein TPP-binding. (333 aa)
Pars_2278PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: pis:Pisl_0325 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (402 aa)
Pars_2279TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pis:Pisl_0324 pyruvate/ketoisovalerate oxidoreductase, gamma subunit. (312 aa)
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.