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glyA glyA eno eno fbp fbp Pars_0193 Pars_0193 Pars_0194 Pars_0194 Pars_0195 Pars_0195 Pars_0196 Pars_0196 Pars_0472 Pars_0472 Pars_0510 Pars_0510 Pars_0511 Pars_0511 Pars_0515 Pars_0515 Pars_0616 Pars_0616 acsA acsA Pars_0952 Pars_0952 Pars_0953 Pars_0953 Pars_0954 Pars_0954 ppcA ppcA Pars_1308 Pars_1308 Pars_1445 Pars_1445 apgM apgM Pars_1571 Pars_1571 Pars_1705 Pars_1705 Pars_1706 Pars_1706 Pars_1707 Pars_1707 Pars_1708 Pars_1708 Pars_1736 Pars_1736 Pars_1830 Pars_1830 Pars_1870 Pars_1870 Pars_2080 Pars_2080 Pars_2277 Pars_2277 Pars_2278 Pars_2278 Pars_2279 Pars_2279
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (419 aa)
fbpFructose-bisphosphate aldolase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (406 aa)
Pars_0193KEGG: pai:PAE1040 pyruvate ferredoxin oxidoreductase gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase. (175 aa)
Pars_0194TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pis:Pisl_1231 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit. (102 aa)
Pars_0195Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE1042 pyruvate ferredoxin oxidoreductase alpha subunit. (393 aa)
Pars_0196Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE1043 pyruvate ferredoxin oxidoreductase beta subunit. (314 aa)
Pars_0472Glycerate 2-kinase; PFAM: MOFRL domain protein; KEGG: pai:PAE1309 hypothetical protein. (442 aa)
Pars_0510Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; KEGG: pis:Pisl_1888 phosphoenolpyruvate synthase. (334 aa)
Pars_0511PFAM: PEP-utilising enzyme, mobile region; KEGG: gme:Gmet_2100 hypothetical protein. (594 aa)
Pars_0515PFAM: PEP-utilising enzyme, mobile region; KEGG: rxy:Rxyl_1575 PEP-utilising enzyme, mobile region. (546 aa)
Pars_0616PFAM: sugar isomerase (SIS); KEGG: pis:Pisl_1579 sugar isomerase (SIS). (201 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (670 aa)
Pars_0952KEGG: pai:PAE2660 formate dehydrogenase, cytochrome b556 subunit (formate dehydrogenase gamma subunit). (233 aa)
Pars_0953PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE2661 formate dehydrogenase beta subunit. (284 aa)
Pars_0954Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: pai:PAE2662 formate dehydrogenase alpha subunit. (1168 aa)
ppcAPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (460 aa)
Pars_1308PFAM: AMP-dependent synthetase and ligase; KEGG: pis:Pisl_0218 AMP-dependent synthetase and ligase. (633 aa)
Pars_1445Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (812 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (411 aa)
Pars_1571PFAM: Lactate/malate dehydrogenase; KEGG: pai:PAE2370 malate dehydrogenase; Belongs to the LDH/MDH superfamily. (309 aa)
Pars_1705PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE3274 2-ketoacid ferredoxin oxidoreductase beta subunit. (299 aa)
Pars_1706PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE3275 2-ketoacid ferredoxin oxidoreductase alpha subunit. (384 aa)
Pars_1707TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE3276 2-ketoacid ferredoxin oxidoreductase delta subunit. (82 aa)
Pars_1708TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pai:PAE3279 2-ketoacid ferredoxin oxidoreductase gamma subunit. (182 aa)
Pars_1736PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pai:PAE3320 D-3-phosphoglycerate dehydrogenase. (307 aa)
Pars_18303-hexulose-6-phosphate synthase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: pai:PAE1679 D-arabino 3-hexulose 6-phosphate formaldehyde lyase, conjectural. (221 aa)
Pars_1870Serine--glyoxylate transaminase; PFAM: aminotransferase, class V; KEGG: pai:PAE3447 aminotransferase, class-V. (389 aa)
Pars_2080Phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pai:PAE2017 phosphoserine phosphatase. (208 aa)
Pars_2277PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pis:Pisl_0326 thiamine pyrophosphate enzyme domain protein TPP-binding. (333 aa)
Pars_2278PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: pis:Pisl_0325 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (402 aa)
Pars_2279TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pis:Pisl_0324 pyruvate/ketoisovalerate oxidoreductase, gamma subunit. (312 aa)
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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