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acn | Aconitate hydratase precursor. (755 aa) | ||||
metH | Methionine synthase. (896 aa) | ||||
metH-2 | Methionine synthase. (337 aa) | ||||
aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (347 aa) | ||||
cbs | Putative cystathionine beta-synthase. (345 aa) | ||||
aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (175 aa) | ||||
metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (770 aa) | ||||
aroF | Phospho-2-dehydro-3-deoxyheptonate aldolase. (360 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (354 aa) | ||||
gapA | Glyceraldehyde-3-phosphate dehydrogenase A; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) | ||||
pfkA | 6-phosphofructokinase isozyme 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa) | ||||
lysC | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. (414 aa) | ||||
rpe | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa) | ||||
aspC | Aspartate aminotransferase. (417 aa) | ||||
glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) | ||||
aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (410 aa) | ||||
cysE | Serine acetyltransferase. (183 aa) | ||||
eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) | ||||
gltA2 | Citrate synthase 1; Belongs to the citrate synthase family. (428 aa) | ||||
fbaA | Fructose-bisphosphate aldolase class 2; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (356 aa) | ||||
pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (400 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (335 aa) | ||||
pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (396 aa) | ||||
aspC-2 | Aspartate aminotransferase. (398 aa) | ||||
rpiB | Ribose-5-phosphate isomerase B. (143 aa) | ||||
aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (140 aa) | ||||
prs | Ribose-phosphate pyrophosphokinase. (312 aa) | ||||
glnA | Glutamine synthetase. (731 aa) | ||||
metK | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (426 aa) | ||||
slcC | (S)-sulfolactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa) | ||||
thrA | Bifunctional aspartokinase/homoserine dehydrogenase 1. (512 aa) | ||||
argD | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (393 aa) | ||||
cysE-2 | Serine acetyltransferase. (279 aa) | ||||
cysK | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (303 aa) | ||||
aroE | Shikimate dehydrogenase. (241 aa) | ||||
mtnN | 5'-methylthioadenosine/S- adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (238 aa) | ||||
sdaA | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. (473 aa) | ||||
ilvK | Branched-chain-amino-acid aminotransferase 2; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (357 aa) | ||||
dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (253 aa) | ||||
dxs | 1-deoxy-D-xylulose-5-phosphate synthase. (314 aa) | ||||
tkt | Transketolase. (283 aa) | ||||
pheA | Prephenate dehydratase. (287 aa) | ||||
pgk/tpi | Bifunctional PGK/TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) | ||||
trpE | Anthranilate synthase component 1. (453 aa) | ||||
pabA | Aminodeoxychorismate synthase component 2. (190 aa) | ||||
trpGD | Bifunctional protein TrpGD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (328 aa) | ||||
trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (258 aa) | ||||
trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) | ||||
trpA | Tryptophan synthase alpha chain. (244 aa) | ||||
icd | Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (738 aa) | ||||
asnB | Asparagine synthetase B [glutamine-hydrolyzing]. (556 aa) | ||||
gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa) | ||||
serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa) | ||||
serA | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa) | ||||
dapD | 2,3,4,5-tetrahydropyridine-2, 6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (270 aa) | ||||
dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (232 aa) | ||||
AB406_2144 | Aspartate aminotransferase. (380 aa) | ||||
dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa) | ||||
tyrA | T-protein. (280 aa) |