(11 nodes) Lysosomal microautophagy network (Aspergillus terreus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATEG_09874	Vacuolar transporter chaperone 4. (810 aa)
	atg15	Putative lipase atg15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. (613 aa)
	ATEG_01876	Uncharacterized protein; Belongs to the OSBP family. (1734 aa)
	ATEG_03283	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (810 aa)
	ATEG_04693	ATG11 domain-containing protein. (1328 aa)
	atg1	Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (964 aa)
	ATEG_05618	Uncharacterized protein. (648 aa)
	ATEG_08309	Uncharacterized protein. (257 aa)
	ATEG_08576	Vacuolar transporter chaperone 1. (122 aa)
	ATEG_08952	PH domain-containing protein. (948 aa)
	ATEG_09510	Uncharacterized protein; Belongs to the OSBP family. (445 aa)

Your Current Organism:

Aspergillus terreus

NCBI taxonomy Id: 341663
Other names: A. terreus NIH2624, Aspergillus terreus FGSC A1156, Aspergillus terreus NIH2624

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATEG_01876	ATEG_04693	Q0CWQ8	Q0CNP1	Uncharacterized protein; Belongs to the OSBP family.	ATG11 domain-containing protein.	0.519
ATEG_01876	ATEG_08952	Q0CWQ8	Q0CBI2	Uncharacterized protein; Belongs to the OSBP family.	PH domain-containing protein.	0.470
ATEG_01876	ATEG_09510	Q0CWQ8	Q0C9X4	Uncharacterized protein; Belongs to the OSBP family.	Uncharacterized protein; Belongs to the OSBP family.	0.632
ATEG_01876	ATEG_09874	Q0CWQ8	Q0C8W0	Uncharacterized protein; Belongs to the OSBP family.	Vacuolar transporter chaperone 4.	0.406
ATEG_03283	ATEG_04693	Q0CSQ1	Q0CNP1	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	ATG11 domain-containing protein.	0.982
ATEG_03283	ATEG_05618	Q0CSQ1	Q0CL16	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Uncharacterized protein.	0.708
ATEG_03283	ATEG_08309	Q0CSQ1	Q0CDC5	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Uncharacterized protein.	0.519
ATEG_03283	atg1	Q0CSQ1	Q0CLX3	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...]	0.998
ATEG_03283	atg15	Q0CSQ1	Q0CXU6	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Putative lipase atg15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity); Belongs to the AB hydrolase superfamily. Lipase family.	0.544
ATEG_04693	ATEG_01876	Q0CNP1	Q0CWQ8	ATG11 domain-containing protein.	Uncharacterized protein; Belongs to the OSBP family.	0.519
ATEG_04693	ATEG_03283	Q0CNP1	Q0CSQ1	ATG11 domain-containing protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.982
ATEG_04693	ATEG_05618	Q0CNP1	Q0CL16	ATG11 domain-containing protein.	Uncharacterized protein.	0.630
ATEG_04693	ATEG_08309	Q0CNP1	Q0CDC5	ATG11 domain-containing protein.	Uncharacterized protein.	0.527
ATEG_04693	atg1	Q0CNP1	Q0CLX3	ATG11 domain-containing protein.	Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...]	0.996
ATEG_04693	atg15	Q0CNP1	Q0CXU6	ATG11 domain-containing protein.	Putative lipase atg15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity); Belongs to the AB hydrolase superfamily. Lipase family.	0.518
ATEG_05618	ATEG_03283	Q0CL16	Q0CSQ1	Uncharacterized protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.708
ATEG_05618	ATEG_04693	Q0CL16	Q0CNP1	Uncharacterized protein.	ATG11 domain-containing protein.	0.630
ATEG_05618	ATEG_08309	Q0CL16	Q0CDC5	Uncharacterized protein.	Uncharacterized protein.	0.998
ATEG_05618	atg1	Q0CL16	Q0CLX3	Uncharacterized protein.	Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...]	0.688
ATEG_05618	atg15	Q0CL16	Q0CXU6	Uncharacterized protein.	Putative lipase atg15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity); Belongs to the AB hydrolase superfamily. Lipase family.	0.977