Groups of genes that are frequently observed in each other's genomic neighborhood.
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Databases
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATEG_08509
HMA domain-containing protein. (91 aa)
ATEG_05976
Ldi domain-containing protein. (561 aa)
ATEG_04404
HMA domain-containing protein. (247 aa)
ATEG_01733
Protein SCO2, mitochondrial. (291 aa)
Your Current Organism:
Aspergillus terreus
NCBI taxonomy Id: 341663 Other names: A. terreus NIH2624, Aspergillus terreus FGSC A1156, Aspergillus terreus NIH2624