(32 nodes) Valine, leucine and isoleucine biosynthesis network (Aspergillus terreus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATEG_08913	Uncharacterized protein. (812 aa)
	ATEG_00685	Uncharacterized protein. (708 aa)
	ATEG_00782	HET domain-containing protein. (716 aa)
	ATEG_00848	2-isopropylmalate synthase. (627 aa)
	ATEG_01080	Dihydroxy-acid dehydratase. (610 aa)
	ATEG_01450	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
	ATEG_02317	Uncharacterized protein. (650 aa)
	ATEG_02963	Uncharacterized protein. (205 aa)
	ATEG_03017	PALP domain-containing protein. (355 aa)
	ATEG_03068	Acetolactate synthase. (586 aa)
	ATEG_03098	Dihydroxy-acid dehydratase. (590 aa)
	ATEG_03407	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (536 aa)
	ATEG_03508	PALP domain-containing protein. (254 aa)
	ATEG_03509	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (400 aa)
	ATEG_03890	HET domain-containing protein. (586 aa)
	ATEG_04415	Dihydroxy-acid dehydratase. (598 aa)
	ATEG_04478	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (395 aa)
	ATEG_04565	Acetolactate synthase. (636 aa)
	ATEG_04923	Uncharacterized protein. (369 aa)
	ATEG_05203	Uncharacterized protein. (1284 aa)
	ATEG_05216	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (365 aa)
	ATEG_05389	Threonine dehydratase. (564 aa)
	ATEG_05420	PALP domain-containing protein. (459 aa)
	ATEG_05490	Acetolactate synthase small subunit, mitochondrial. (323 aa)
	ATEG_05627	TPP_enzyme_N domain-containing protein. (194 aa)
	ATEG_06808	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (413 aa)
	ATEG_08346	Acetolactate synthase. (635 aa)
	ATEG_08370	Zn(2)-C6 fungal-type domain-containing protein. (408 aa)
	ATEG_08702	Uncharacterized protein. (627 aa)
	ATEG_09576	Uncharacterized protein. (224 aa)
	ATEG_10023	Uncharacterized protein. (325 aa)
	ATEG_10170	Uncharacterized protein. (597 aa)

Your Current Organism:

Aspergillus terreus

NCBI taxonomy Id: 341663
Other names: A. terreus NIH2624, Aspergillus terreus FGSC A1156, Aspergillus terreus NIH2624

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATEG_00685	ATEG_00848	Q0D049	Q0CZN6	Uncharacterized protein.	2-isopropylmalate synthase.	0.726
ATEG_00685	ATEG_01080	Q0D049	Q0CZ04	Uncharacterized protein.	Dihydroxy-acid dehydratase.	0.492
ATEG_00685	ATEG_01450	Q0D049	Q0CXY4	Uncharacterized protein.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.843
ATEG_00685	ATEG_02317	Q0D049	Q0CVG7	Uncharacterized protein.	Uncharacterized protein.	0.492
ATEG_00685	ATEG_02963	Q0D049	Q0CTM1	Uncharacterized protein.	Uncharacterized protein.	0.407
ATEG_00685	ATEG_03017	Q0D049	Q0CTG7	Uncharacterized protein.	PALP domain-containing protein.	0.407
ATEG_00685	ATEG_03068	Q0D049	Q0CTB6	Uncharacterized protein.	Acetolactate synthase.	0.538
ATEG_00685	ATEG_03098	Q0D049	Q0CT86	Uncharacterized protein.	Dihydroxy-acid dehydratase.	0.492
ATEG_00685	ATEG_03508	Q0D049	Q0CS26	Uncharacterized protein.	PALP domain-containing protein.	0.520
ATEG_00685	ATEG_04415	Q0D049	Q0CPG9	Uncharacterized protein.	Dihydroxy-acid dehydratase.	0.492
ATEG_00685	ATEG_04565	Q0D049	Q0CP19	Uncharacterized protein.	Acetolactate synthase.	0.538
ATEG_00685	ATEG_05389	Q0D049	Q0CLP5	Uncharacterized protein.	Threonine dehydratase.	0.520
ATEG_00685	ATEG_05420	Q0D049	Q0CLL4	Uncharacterized protein.	PALP domain-containing protein.	0.407
ATEG_00685	ATEG_05490	Q0D049	Q0CLE4	Uncharacterized protein.	Acetolactate synthase small subunit, mitochondrial.	0.833
ATEG_00685	ATEG_05627	Q0D049	Q0CL07	Uncharacterized protein.	TPP_enzyme_N domain-containing protein.	0.538
ATEG_00685	ATEG_06808	Q0D049	Q0CHM6	Uncharacterized protein.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.428
ATEG_00685	ATEG_08346	Q0D049	Q0CD88	Uncharacterized protein.	Acetolactate synthase.	0.538
ATEG_00685	ATEG_08702	Q0D049	Q0CC82	Uncharacterized protein.	Uncharacterized protein.	0.492
ATEG_00685	ATEG_08913	Q0D049	Q0CBM1	Uncharacterized protein.	Uncharacterized protein.	0.829
ATEG_00685	ATEG_10170	Q0D049	Q0C814	Uncharacterized protein.	Uncharacterized protein.	0.492