STRINGSTRING
adhE adhE lipB lipB garD garD uxaB_1 uxaB_1 exuT exuT eda eda iolC iolC uxaC uxaC gno gno kduI kduI fucP fucP fadK fadK eno eno gltA2 gltA2 fabV fabV gap gap butA butA fumC fumC EGI89_05125 EGI89_05125 xlnD_1 xlnD_1 calB calB GCA_000805695_00495 GCA_000805695_00495 fabH_5 fabH_5 gabD1 gabD1 accA accA thlA thlA mutB mutB GCA_000805695_00636 GCA_000805695_00636 MeaB MeaB fbp fbp acnB acnB acn acn sucC sucC accD5 accD5 algC algC pgcA pgcA maeB_2 maeB_2 pdhC_3 pdhC_3 bfmBAB bfmBAB paaK_2 paaK_2 kstR2_1 kstR2_1 hmp_2 hmp_2 paaA paaA EGI89_11385 EGI89_11385 paaC paaC PaaJ PaaJ echA8_2 echA8_2 paaH paaH paaI paaI pcaF_2 pcaF_2 yrdA_2 yrdA_2 boxD boxD pksH pksH hmp_1 hmp_1 acs_2 acs_2 lpd_2 lpd_2 fabH_3 fabH_3 gabD gabD EGI89_08280 EGI89_08280 algA_2 algA_2 pyk pyk fabF_1 fabF_1 pckA pckA deoC1 deoC1 icd icd echA8_1 echA8_1 GCA_000805695_01229 GCA_000805695_01229 GCA_000805695_01230 GCA_000805695_01230 GCA_000805695_01231 GCA_000805695_01231 GCA_000805695_01232 GCA_000805695_01232 GCA_000805695_01233 GCA_000805695_01233 LpdA LpdA LpdA-2 LpdA-2 GCA_000805695_01259 GCA_000805695_01259 algA_3 algA_3 GCA_000805695_01275 GCA_000805695_01275 pdhB_2 pdhB_2 EGI89_05445 EGI89_05445 pdhC_1 pdhC_1 fabG_5 fabG_5 GCA_000805695_01489 GCA_000805695_01489 pgk pgk rpiB rpiB prs prs ppc ppc acs_1 acs_1 gapA_2 gapA_2 pfkA_1 pfkA_1 GCA_000805695_01737 GCA_000805695_01737 algA_1 algA_1 poxB poxB pgi pgi scpC_2 scpC_2 nahG nahG scpA_1 scpA_1 fabG_4 fabG_4 fabF_4 fabF_4 lpdG lpdG ycdF ycdF tal tal fabH_2 fabH_2 lpd_1 lpd_1 scoB scoB scoA scoA lplJ lplJ yngG yngG pdhB_1 pdhB_1 acoD acoD GCA_000805695_02217 GCA_000805695_02217 tpiA tpiA EGI89_11265 EGI89_11265 pcaF_1 pcaF_1 EGI89_11280 EGI89_11280 mce mce aceA aceA aceB aceB GCA_000805695_02394 GCA_000805695_02394 scpA_2 scpA_2 acoA acoA pdhC_2 pdhC_2 GCA_000805695_02437 GCA_000805695_02437 birA birA lipA lipA GCA_000805695_02557 GCA_000805695_02557 accC accC accB accB acsA acsA fabH_4 fabH_4 ghrA ghrA frdB frdB frdA frdA GCA_000805695_02701 GCA_000805695_02701 GCA_000805695_02724 GCA_000805695_02724 sucD sucD GCA_000805695_02773 GCA_000805695_02773 paaK_1 paaK_1 GCA_000805695_02810 GCA_000805695_02810 GCA_000805695_02811 GCA_000805695_02811 GCA_000805695_02812 GCA_000805695_02812 icaA_1 icaA_1 EGI89_12080 EGI89_12080 GCA_000805695_02815 GCA_000805695_02815 GCA_000805695_02816 GCA_000805695_02816 lolA lolA pdaA pdaA GCA_000805695_02819 GCA_000805695_02819 fabF_3 fabF_3 GCA_000805695_02821 GCA_000805695_02821 GCA_000805695_02822 GCA_000805695_02822 fabF_2 fabF_2 GCA_000805695_02824 GCA_000805695_02824 ybhR_1 ybhR_1 ybhF_1 ybhF_1 GCA_000805695_02827 GCA_000805695_02827 GCA_000805695_02828 GCA_000805695_02828 GCA_000805695_02829 GCA_000805695_02829 EGI89_12160 EGI89_12160 fabH_1 fabH_1 GCA_000805695_02832 GCA_000805695_02832 GCA_000805695_02833 GCA_000805695_02833 acpP acpP fabB fabB fabG_2 fabG_2 GCA_000805695_02838 GCA_000805695_02838 EGI89_07445 EGI89_07445 sucB sucB sucA sucA scpC_1 scpC_1 GCA_000805695_02931 GCA_000805695_02931 GCA_000805695_02932 GCA_000805695_02932 GCA_000805695_02933 GCA_000805695_02933 GCA_000805695_02934 GCA_000805695_02934 rpe rpe ldhA ldhA csxA csxA fadB2 fadB2 gpmI gpmI etfB etfB etfA etfA mqo mqo accD accD fbaA fbaA dxs_2 dxs_2 tktB tktB phnP phnP fabD fabD GCA_000805695_03472 GCA_000805695_03472 desA1 desA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adhEUnannotated protein. (383 aa)
lipBUnannotated protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (245 aa)
garDUnannotated protein. (537 aa)
uxaB_1Unannotated protein. (485 aa)
exuTUnannotated protein. (506 aa)
edaUnannotated protein. (224 aa)
iolCUnannotated protein. (335 aa)
uxaCUnannotated protein. (465 aa)
gnoUnannotated protein. (260 aa)
kduIUnannotated protein; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa)
fucPUnannotated protein. (574 aa)
fadKUnannotated protein. (546 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
gltA2Unannotated protein; Belongs to the citrate synthase family. (427 aa)
fabVUnannotated protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (400 aa)
gapUnannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (479 aa)
butAUnannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (229 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
EGI89_05125Unannotated protein. (153 aa)
xlnD_1Unannotated protein. (383 aa)
calBUnannotated protein; Belongs to the aldehyde dehydrogenase family. (490 aa)
GCA_000805695_00495Unannotated protein. (379 aa)
fabH_5Unannotated protein. (374 aa)
gabD1Unannotated protein. (457 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
thlAUnannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
mutBUnannotated protein. (710 aa)
GCA_000805695_00636Unannotated protein. (347 aa)
MeaBUnannotated protein. (322 aa)
fbpUnannotated protein; Belongs to the FBPase class 1 family. (338 aa)
acnBUnannotated protein. (920 aa)
acnUnannotated protein. (754 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
accD5Unannotated protein. (542 aa)
algCUnannotated protein. (460 aa)
pgcAUnannotated protein. (571 aa)
maeB_2Unannotated protein. (754 aa)
pdhC_3Unannotated protein. (419 aa)
bfmBABUnannotated protein. (685 aa)
paaK_2Unannotated protein; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (445 aa)
kstR2_1Unannotated protein. (190 aa)
hmp_2Unannotated protein. (360 aa)
paaAUnannotated protein. (321 aa)
EGI89_11385Unannotated protein. (95 aa)
paaCUnannotated protein. (258 aa)
PaaJUnannotated protein. (162 aa)
echA8_2Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
paaHUnannotated protein. (385 aa)
paaIUnannotated protein. (137 aa)
pcaF_2Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
yrdA_2Unannotated protein. (197 aa)
boxDUnannotated protein. (683 aa)
pksHUnannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (251 aa)
hmp_1Unannotated protein. (349 aa)
acs_2Unannotated protein. (635 aa)
lpd_2Unannotated protein. (466 aa)
fabH_3Unannotated protein. (352 aa)
gabDUnannotated protein; Belongs to the aldehyde dehydrogenase family. (509 aa)
EGI89_08280Unannotated protein. (388 aa)
algA_2Unannotated protein. (330 aa)
pykUnannotated protein; Belongs to the pyruvate kinase family. (480 aa)
fabF_1Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (523 aa)
deoC1Unannotated protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (247 aa)
icdUnannotated protein; Belongs to the monomeric-type IDH family. (736 aa)
echA8_1Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
GCA_000805695_01229Unannotated protein. (356 aa)
GCA_000805695_01230Unannotated protein. (182 aa)
GCA_000805695_01231Unannotated protein. (402 aa)
GCA_000805695_01232Unannotated protein. (563 aa)
GCA_000805695_01233Unannotated protein. (249 aa)
LpdAUnannotated protein. (467 aa)
LpdA-2Unannotated protein. (470 aa)
GCA_000805695_01259Unannotated protein. (285 aa)
algA_3Unannotated protein. (364 aa)
GCA_000805695_01275Unannotated protein. (246 aa)
pdhB_2Unannotated protein. (835 aa)
EGI89_05445Unannotated protein. (380 aa)
pdhC_1Unannotated protein. (447 aa)
fabG_5Unannotated protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
GCA_000805695_01489Unannotated protein. (201 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (396 aa)
rpiBUnannotated protein. (146 aa)
prsUnannotated protein. (320 aa)
ppcUnannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (849 aa)
acs_1Unannotated protein. (565 aa)
gapA_2Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
pfkA_1Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
GCA_000805695_01737Unannotated protein. (204 aa)
algA_1Unannotated protein. (116 aa)
poxBUnannotated protein; Belongs to the TPP enzyme family. (577 aa)
pgiUnannotated protein; Belongs to the GPI family. (550 aa)
scpC_2Unannotated protein. (421 aa)
nahGUnannotated protein. (485 aa)
scpA_1Unannotated protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1153 aa)
fabG_4Unannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (239 aa)
fabF_4Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
lpdGUnannotated protein. (467 aa)
ycdFUnannotated protein. (250 aa)
talUnannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
fabH_2Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (337 aa)
lpd_1Unannotated protein. (466 aa)
scoBUnannotated protein. (218 aa)
scoAUnannotated protein. (256 aa)
lplJUnannotated protein. (328 aa)
yngGUnannotated protein. (288 aa)
pdhB_1Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
acoDUnannotated protein; Belongs to the aldehyde dehydrogenase family. (501 aa)
GCA_000805695_02217Unannotated protein. (344 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
EGI89_11265Unannotated protein. (799 aa)
pcaF_1Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
EGI89_11280Unannotated protein. (600 aa)
mceUnannotated protein. (132 aa)
aceAUnannotated protein. (425 aa)
aceBUnannotated protein; Belongs to the malate synthase family. (528 aa)
GCA_000805695_02394Unannotated protein. (495 aa)
scpA_2Unannotated protein. (424 aa)
acoAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (334 aa)
pdhC_2Unannotated protein. (534 aa)
GCA_000805695_02437Unannotated protein. (204 aa)
birAUnannotated protein. (237 aa)
lipAUnannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (289 aa)
GCA_000805695_02557Unannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
accCUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
accBUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (160 aa)
acsAUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (634 aa)
fabH_4Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)
ghrAUnannotated protein. (308 aa)
frdBUnannotated protein. (256 aa)
frdAUnannotated protein. (670 aa)
GCA_000805695_02701Unannotated protein. (230 aa)
GCA_000805695_02724Unannotated protein. (88 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
GCA_000805695_02773Unannotated protein. (313 aa)
paaK_1Unannotated protein. (435 aa)
GCA_000805695_02810Unannotated protein. (551 aa)
GCA_000805695_02811Unannotated protein. (523 aa)
GCA_000805695_02812Unannotated protein. (1219 aa)
icaA_1Unannotated protein. (394 aa)
EGI89_12080Unannotated protein. (160 aa)
GCA_000805695_02815Unannotated protein. (123 aa)
GCA_000805695_02816Unannotated protein. (207 aa)
lolAUnannotated protein. (153 aa)
pdaAUnannotated protein. (257 aa)
GCA_000805695_02819Unannotated protein. (329 aa)
fabF_3Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (398 aa)
GCA_000805695_02821Unannotated protein. (85 aa)
GCA_000805695_02822Unannotated protein. (179 aa)
fabF_2Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (373 aa)
GCA_000805695_02824Unannotated protein. (145 aa)
ybhR_1Unannotated protein. (425 aa)
ybhF_1Unannotated protein. (241 aa)
GCA_000805695_02827Unannotated protein. (333 aa)
GCA_000805695_02828Unannotated protein. (134 aa)
GCA_000805695_02829Unannotated protein. (151 aa)
EGI89_12160Unannotated protein. (146 aa)
fabH_1Unannotated protein. (379 aa)
GCA_000805695_02832Unannotated protein. (303 aa)
GCA_000805695_02833Unannotated protein. (289 aa)
acpPUnannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (82 aa)
fabBUnannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa)
fabG_2Unannotated protein. (243 aa)
GCA_000805695_02838Unannotated protein. (413 aa)
EGI89_07445Unannotated protein. (288 aa)
sucBUnannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (410 aa)
sucAUnannotated protein. (929 aa)
scpC_1Unannotated protein. (503 aa)
GCA_000805695_02931Unannotated protein. (214 aa)
GCA_000805695_02932Unannotated protein. (363 aa)
GCA_000805695_02933Unannotated protein. (72 aa)
GCA_000805695_02934Unannotated protein. (349 aa)
rpeUnannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (215 aa)
ldhAUnannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
csxAUnannotated protein. (825 aa)
fadB2Unannotated protein. (296 aa)
gpmIUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (504 aa)
etfBUnannotated protein. (248 aa)
etfAUnannotated protein. (318 aa)
mqoUnannotated protein. (491 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (282 aa)
fbaAUnannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (355 aa)
dxs_2Unannotated protein. (314 aa)
tktBUnannotated protein. (281 aa)
phnPUnannotated protein. (260 aa)
fabDUnannotated protein. (292 aa)
GCA_000805695_03472Unannotated protein. (452 aa)
desA1Unannotated protein. (333 aa)
Your Current Organism:
Empedobacter falsenii
NCBI taxonomy Id: 343874
Other names: CCUG 51536, CIP 108861, E. falsenii, Empedobacter falsenii (Kampfer et al. 2006) Zhang et al. 2014, Wautersiella falsenii, Wautersiella falsenii (Kampfer et al. 2006) emend. Zhang et al. 2014, strain NF 993
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