STRINGSTRING
setA setA secM secM ampD ampD ampE ampE yacL yacL ACD07584.1 ACD07584.1 dgt dgt yaeH yaeH frsA frsA crl crl aroM aroM ACD08816.1 ACD08816.1 ACD07115.1 ACD07115.1 ACD07805.1 ACD07805.1 ACD07470.1 ACD07470.1 ACD06350.1 ACD06350.1 ompC ompC proQ proQ ACD09396.1 ACD09396.1 ACD08599.1 ACD08599.1 ACD09321.1 ACD09321.1 ACD09001.1 ACD09001.1 ACD06839.1 ACD06839.1 ACD08780.1 ACD08780.1 ACD08501.1 ACD08501.1 ACD07684.1 ACD07684.1 yeeX yeeX ACD06657.1 ACD06657.1 ACD08388.1 ACD08388.1 yciU yciU ACD10326.1 ACD10326.1 ACD09475.1 ACD09475.1 lapA lapA lapB lapB ompN ompN ACD06960.1 ACD06960.1 ACD10349.1 ACD10349.1 ydgH ydgH tus tus ACD07143.1 ACD07143.1 lpp lpp ACD09414.1 ACD09414.1 ACD07013.1 ACD07013.1 osmE osmE spy spy yoaH yoaH ACD06331.1 ACD06331.1 yobD yobD ACD06738.1 ACD06738.1 ACD08424.1 ACD08424.1 ACD10068.1 ACD10068.1 ACD09265.1 ACD09265.1 cutC cutC ACD07364.1 ACD07364.1 ndh ndh ycfP ycfP lpoB lpoB ACD07127.1 ACD07127.1 hinT hinT ACD10123.1 ACD10123.1 ACD07512.1 ACD07512.1 ACD10134.1 ACD10134.1 mdoC mdoC hspQ hspQ matP matP zapC zapC mukB mukB mukE mukE mukF mukF smtA smtA ACD07104.1 ACD07104.1 ACD08495.1 ACD08495.1 lolA lolA ACD09180.1 ACD09180.1 ompX ompX ACD10063.1 ACD10063.1 yfbU yfbU ACD07669.1 ACD07669.1 ACD06578.1 ACD06578.1 ACD08227.1 ACD08227.1 ypfN ypfN sseB sseB ACD08524.1 ACD08524.1 ACD08249.1 ACD08249.1 iap iap ACD06427.1 ACD06427.1 ACD06853.1 ACD06853.1 stpA stpA ACD10360.1 ACD10360.1 ACD08215.1 ACD08215.1 ACD09097.1 ACD09097.1 ACD09818.1 ACD09818.1 mzrA mzrA ACD06520.1 ACD06520.1 ACD09454.1 ACD09454.1 ACD07858.1 ACD07858.1 aaeX aaeX aaeB aaeB ACD06751.1 ACD06751.1 ycfR ycfR sfsB sfsB ACD09538.1 ACD09538.1 tsgA tsgA damX damX uspB uspB ACD07558.1 ACD07558.1 ACD06823.1 ACD06823.1 ACD10333.1 ACD10333.1 ACD06902.1 ACD06902.1 mtlR mtlR ACD07027.1 ACD07027.1 ACD06701.1 ACD06701.1 ACD10382.1 ACD10382.1 viaA viaA atpI atpI ACD10111.1 ACD10111.1 ACD10436.1 ACD10436.1 ACD08875.1 ACD08875.1 cpxP cpxP ACD09654.1 ACD09654.1 ACD09861.1 ACD09861.1 zapB zapB fabR fabR ACD09970.1 ACD09970.1 ACD07098.1 ACD07098.1 pspG pspG ACD09317.1 ACD09317.1 ACD08578.1 ACD08578.1 ACD08172.1 ACD08172.1 ACD09910.1 ACD09910.1 ACD07163.1 ACD07163.1 mdoB mdoB ACD08817.1 ACD08817.1 trpR trpR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
setASugar efflux transporter A; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899. (360 aa)
secMSecretion monitor protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family. (195 aa)
ampDN-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01510. (183 aa)
ampEProtein AmpE. (284 aa)
yacLConserved hypothetical protein; Identified by match to protein family HMM PF06062; Belongs to the UPF0231 family. (120 aa)
ACD07584.1Conserved hypothetical protein. (115 aa)
dgtDeoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. (505 aa)
yaeHConserved hypothetical protein; Belongs to the UPF0325 family. (128 aa)
frsAFermentation-respiration switch protein; Displays esterase activity toward pNP-butyrate. (414 aa)
crlSigma factor-binding protein Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (133 aa)
aroMAroM protein; Identified by match to protein family HMM PF07302. (225 aa)
ACD08816.1Putative lipoprotein; Identified by match to protein family HMM PF03923. (192 aa)
ACD07115.1Bacterial extracellular solute-binding protein, family 5; Identified by match to protein family HMM PF00496. (566 aa)
ACD07805.1Haemolysin expression modulating protein; Identified by match to protein family HMM PF05321. (72 aa)
ACD07470.1Conserved hypothetical protein; Identified by similarity to GB:AAN79258.1. (68 aa)
ACD06350.1Cyd operon protein YbgE; Identified by match to protein family HMM PF09600; match to protein family HMM TIGR02112. (97 aa)
ompCIdentified by match to protein family HMM PF00267; Belongs to the Gram-negative porin family. (376 aa)
proQProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. (119 aa)
ACD09396.1Conserved hypothetical protein. (114 aa)
ACD08599.1Putative membrane protein; Identified by match to protein family HMM PF04171; match to protein family HMM PF04235. (385 aa)
ACD09321.1Identified by match to protein family HMM PF06316. (199 aa)
ACD09001.1Outer membrane porin protein LC; Identified by match to protein family HMM PF00267. (175 aa)
ACD06839.1Conserved hypothetical protein. (74 aa)
ACD08780.1Chain length determinant protein; Identified by match to protein family HMM PF02706. (344 aa)
ACD08501.1Putative membrane protein. (226 aa)
ACD07684.1Inner membrane protein YeeA. (142 aa)
yeeXConserved hypothetical protein; Identified by match to protein family HMM PF04363; Belongs to the UPF0265 family. (109 aa)
ACD06657.1HTH-type transcriptional regulator MlrA. (179 aa)
ACD08388.1Identified by match to protein family HMM PF00816; Belongs to the histone-like protein H-NS family. (137 aa)
yciUConserved hypothetical protein; Identified by match to protein family HMM PF04269; Belongs to the UPF0263 family. (109 aa)
ACD10326.1Identified by match to protein family HMM PF06316. (199 aa)
ACD09475.1Conserved hypothetical protein. (83 aa)
lapAConserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa)
lapBTetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa)
ompNIdentified by match to protein family HMM PF00267. (377 aa)
ACD06960.1Conserved hypothetical protein; Identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156. (130 aa)
ACD10349.1Conserved hypothetical protein; Identified by match to protein family HMM PF06649. (101 aa)
ydgHYdgH protein; Identified by match to protein family HMM PF07338. (314 aa)
tusDNA replication terminus site-binding protein; Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence; Belongs to the Tus family. (309 aa)
ACD07143.1Haemolysin expression modulating protein; Identified by match to protein family HMM PF05321. (71 aa)
lppMajor outer membrane lipoprotein; Identified by match to protein family HMM PF04728. (78 aa)
ACD09414.1Conserved hypothetical protein; Identified by match to protein family HMM PF04338. (252 aa)
ACD07013.1Conserved hypothetical protein. (178 aa)
osmEOsmotically-inducible lipoprotein E; Identified by match to protein family HMM PF04355. (112 aa)
spyIdentified by match to protein family HMM PF07813. (156 aa)
yoaHConserved hypothetical protein; Identified by match to protein family HMM PF03701; Belongs to the UPF0181 family. (59 aa)
ACD06331.1Conserved hypothetical protein. (254 aa)
yobDConserved hypothetical protein; Identified by match to protein family HMM PF06173. (152 aa)
ACD06738.1Conserved hypothetical protein. (113 aa)
ACD08424.1Identified by match to protein family HMM PF05425. (290 aa)
ACD10068.1Copper resistance protein CopC; Identified by match to protein family HMM PF04234. (124 aa)
ACD09265.1Conserved hypothetical protein; Identified by match to protein family HMM PF04391. (219 aa)
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. (248 aa)
ACD07364.1Conserved hypothetical protein; Identified by match to protein family HMM PF06185. (190 aa)
ndhNADH dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992. (434 aa)
ycfPConserved hypothetical protein; Identified by match to protein family HMM PF05728; Belongs to the UPF0227 family. (180 aa)
lpoBPutative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. (212 aa)
ACD07127.1Putative lipoprotein; Identified by match to protein family HMM PF07233. (125 aa)
hinTPurine nucleoside phosphoramidase; Identified by match to protein family HMM PF01230. (119 aa)
ACD10123.1Conserved hypothetical protein. (56 aa)
ACD07512.1Putative lipoprotein; Identified by match to protein family HMM PF07273. (186 aa)
ACD10134.1Conserved hypothetical protein. (85 aa)
mdoCGlucans biosynthesis protein C; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (385 aa)
hspQHemimethylated DNA-binding protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. (105 aa)
matPConserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. (150 aa)
zapCConserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (192 aa)
mukBChromosome partition protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1486 aa)
mukEChromosome partition protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. (234 aa)
mukFChromosome partition protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa)
smtASmtA protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family. (261 aa)
ACD07104.1Conserved hypothetical protein. (297 aa)
ACD08495.1Conserved hypothetical protein; Identified by match to protein family HMM PF02698. (259 aa)
lolAOuter membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (203 aa)
ACD09180.1Conserved hypothetical protein; Identified by match to protein family HMM PF04393. (330 aa)
ompXOuter membrane protein X; Identified by match to protein family HMM PF06316. (171 aa)
ACD10063.1Conserved hypothetical protein; Identified by match to protein family HMM PF05957. (101 aa)
yfbUYfbU domain protein; Identified by match to protein family HMM PF03887; Belongs to the UPF0304 family. (164 aa)
ACD07669.1Conserved hypothetical protein; Identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743. (94 aa)
ACD06578.1Putative lipoprotein; Identified by match to protein family HMM PF06572. (191 aa)
ACD08227.1Conserved hypothetical protein; Identified by match to protein family HMM PF06674. (347 aa)
ypfNConserved hypothetical protein. (66 aa)
sseBsseB protein; Identified by match to protein family HMM PF07179. (258 aa)
ACD08524.1Putative lipoprotein. (239 aa)
ACD08249.1Putative lipoprotein; Identified by match to protein family HMM PF06004. (75 aa)
iapAlkaline phosphatase isozyme conversion peptidase; Identified by match to protein family HMM PF04389. (345 aa)
ACD06427.1Conserved hypothetical protein; Identified by match to protein family HMM PF05957. (109 aa)
ACD06853.1Conserved hypothetical protein; Identified by match to protein family HMM PF09400. (114 aa)
stpAH-NS histone family protein StpA; Identified by similarity to SP:P0ACG3; match to protein family HMM PF00816; Belongs to the histone-like protein H-NS family. (134 aa)
ACD10360.1Conserved hypothetical protein. (99 aa)
ACD08215.1Conserved hypothetical protein. (134 aa)
ACD09097.1Conserved hypothetical protein; Identified by match to protein family HMM PF05957. (101 aa)
ACD09818.1Conserved hypothetical protein; Identified by match to protein family HMM PF06476. (122 aa)
mzrAConserved hypothetical protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. (127 aa)
ACD06520.1Putative inner membrane protein; Identified by match to protein family HMM PF09335. (220 aa)
ACD09454.1Conserved hypothetical protein. (238 aa)
ACD07858.1Putative lipoprotein; yqhH. (85 aa)
aaeXProtein AaeX; Identified by match to protein family HMM PF07869. (90 aa)
aaeBP-hydroxybenzoic acid efflux pump subunit aaeB; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. (655 aa)
ACD06751.1Conserved hypothetical protein. (90 aa)
ycfRProtein YcfR; Identified by match to protein family HMM PF07338. (87 aa)
sfsBSugar fermentation stimulation protein B. (92 aa)
ACD09538.1Integral membrane protein, YccS/YhfK family; Identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667. (696 aa)
tsgAMajor facilitator family transporter TsgA; Identified by match to protein family HMM PF07690. (393 aa)
damXDamX protein; Non-essential cell division protein. (428 aa)
uspBUniversal stress protein B. (111 aa)
ACD07558.1Putative membrane protein; Identified by match to protein family HMM PF07947. (208 aa)
ACD06823.1Conserved hypothetical protein. (119 aa)
ACD10333.1Peptidase, M16 (pitrilysin) family; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193. (498 aa)
ACD06902.1Putative lipoprotein. (236 aa)
mtlRMannitol operon repressor; Identified by match to protein family HMM PF05068. (195 aa)
ACD07027.1Conserved hypothetical protein. (120 aa)
ACD06701.1Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535. (344 aa)
ACD10382.1Hypothetical protein; Identified by glimmer; putative. (468 aa)
viaAIdentified by match to protein family HMM PF05762. (483 aa)
atpIATP synthase F0, I subunit; Identified by match to protein family HMM PF03899. (126 aa)
ACD10111.1Conserved hypothetical protein. (356 aa)
ACD10436.1Conserved hypothetical protein; Identified by match to protein family HMM PF07119. (135 aa)
ACD08875.1Conserved hypothetical protein; Identified by match to protein family HMM PF06288. (89 aa)
cpxPPeriplasmic protein CpxP; Identified by match to protein family HMM PF07813. (170 aa)
ACD09654.1Conserved hypothetical protein; Identified by match to protein family HMM PF07305. (199 aa)
ACD09861.1Conserved hypothetical protein; Identified by match to protein family HMM PF05656. (129 aa)
zapBConserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (79 aa)
fabRFatty acid biosynthesis regulator; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (215 aa)
ACD09970.1Putative inner membrane protein; Identified by match to protein family HMM PF07226. (119 aa)
ACD07098.1Conserved hypothetical protein; Identified by match to protein family HMM PF04222. (196 aa)
pspGPhage shock protein G; Identified by match to protein family HMM PF09583; match to protein family HMM TIGR02975. (80 aa)
ACD09317.1Putative lipoprotein. (117 aa)
ACD08578.1Conserved hypothetical protein. (65 aa)
ACD08172.1Identified by match to protein family HMM PF04225; match to protein family HMM PF08525. (212 aa)
ACD09910.1Conserved hypothetical protein; Identified by match to protein family HMM PF06526. (68 aa)
ACD07163.1Conserved hypothetical protein; Identified by match to protein family HMM PF09695; match to protein family HMM TIGR01626. (184 aa)
mdoBPhosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa)
ACD08817.1Protein smp precursor. (214 aa)
trpRTrp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (108 aa)
Your Current Organism:
Shigella boydii
NCBI taxonomy Id: 344609
Other names: S. boydii CDC 3083-94, Shigella boydii BS512, Shigella boydii CDC 3083-94, Shigella boydii str. CDC 3083-94, Shigella boydii strain CDC 3083-94
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