STRINGSTRING
trx trx grxC grxC gor gor dsbC dsbC nrdH nrdH cysH cysH cysI cysI ACD07153.1 ACD07153.1 cysJ cysJ grxA grxA trxB trxB dmsC1 dmsC1 grxB grxB ACD10006.1 ACD10006.1 ACD07373.1 ACD07373.1 ACD09801.1 ACD09801.1 ACD09208.1 ACD09208.1 dmsC2 dmsC2 arnT arnT dsbB dsbB msrP msrP dsbE dsbE ahpF ahpF ahpC ahpC lpdA lpdA msrA msrA dsbD dsbD dsbA dsbA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trxThioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family. (109 aa)
grxCGlutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (83 aa)
gorGlutathione-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421. (450 aa)
dsbCThiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (236 aa)
nrdHGlutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194. (81 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (244 aa)
cysISulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa)
ACD07153.1Putative thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family. (139 aa)
cysJSulfite reductase [NADPH] flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. (599 aa)
grxAGlutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02183. (85 aa)
trxBThioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. (321 aa)
dmsC1Anaerobic dimethyl sulfoxide reductase, C subunit; Identified by match to protein family HMM PF04976. (287 aa)
grxBGlutaredoxin, GrxB family; Identified by match to protein family HMM PF02798; match to protein family HMM PF04399; match to protein family HMM TIGR02182. (215 aa)
ACD10006.1GAF domain protein; Identified by match to protein family HMM PF01590. (183 aa)
ACD07373.1Putative membrane protein; Identified by match to protein family HMM PF09335. (235 aa)
ACD09801.1Putative membrane protein; Identified by match to protein family HMM PF09335. (192 aa)
ACD09208.1Putative monothiol glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. (115 aa)
dmsC2Anaerobic dimethyl sulfoxide reductase, C subunit; Identified by match to protein family HMM PF04976. (284 aa)
arnTAnaerobic dimethyl sulfoxide reductase, A subunit; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR02166; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (752 aa)
dsbBDisulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa)
msrPOxidoreductase, molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pa [...] (334 aa)
dsbEThiol:disulfide interchange protein DsbE; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385. (185 aa)
ahpFAlkyl hydroperoxide reductase subunit F; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140. (531 aa)
ahpCAlkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
lpdADihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. (474 aa)
msrAmethionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (212 aa)
dsbDThiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (565 aa)
dsbAThiol:disulfide interchange protein DsbA; Identified by match to protein family HMM PF01323. (208 aa)
Your Current Organism:
Shigella boydii
NCBI taxonomy Id: 344609
Other names: S. boydii CDC 3083-94, Shigella boydii BS512, Shigella boydii CDC 3083-94, Shigella boydii str. CDC 3083-94, Shigella boydii strain CDC 3083-94
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