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| | actP | Cation/acetate symporter ActP; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (549 aa) |
| | nhaA | Sodium/proton antiporter nhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (388 aa) |
| | lspA | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (164 aa) |
| | ftsL | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (121 aa) |
| | ftsW | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (414 aa) |
| | ftsQ | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (276 aa) |
| | aroP | Aromatic amino acid transport protein AroP; Identified by match to protein family HMM PF00324. (456 aa) |
| | ACD09940.1 | PTS system IIA component domain protein; Identified by match to protein family HMM PF03610. (146 aa) |
| | smbA | Protein SbmA; Identified by match to protein family HMM PF05992; match to protein family HMM PF06472. (406 aa) |
| | phoR | Phosphate regulon sensor protein PhoR; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; match to protein family HMM TIGR02966. (431 aa) |
| | yajC | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa) |
| | ACD07151.1 | Transporter, major facilitator family; Identified by match to protein family HMM PF07690. (454 aa) |
| | ppiD | Peptidylprolyl isomerase; Identified by match to protein family HMM PF00639. (623 aa) |
| | ACD06391.1 | Putative membrane protein; Identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245. (259 aa) |
| | crcB | CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (127 aa) |
| | kdpB | K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa) |
| | lnt | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (512 aa) |
| | ACD07623.1 | Peptidase, S54 (rhomboid) family; Identified by match to protein family HMM PF01694; match to protein family HMM TIGR02276. (625 aa) |
| | ACD07049.1 | DnaJ domain protein; Identified by match to protein family HMM PF00226. (483 aa) |
| | dacA | Serine-type D-Ala-D-Ala carboxypeptidase; Identified by match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. (403 aa) |
| | tolQ | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa) |
| | tolR | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa) |
| | rcsC | Sensor histidine kinase/response regulator RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (949 aa) |
| | ccmF | Cytochrome c-type biogenesis protein CcmF; Identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353. (647 aa) |
| | ispZ | Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa) |
| | pgpB | Identified by match to protein family HMM PF01569. (254 aa) |
| | lapA | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa) |
| | zntB | Zinc transport protein ZntB; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (327 aa) |
| | ACD09443.1 | Inner membrane protein YddG; Identified by match to protein family HMM PF00892. (162 aa) |
| | ACD08076.1 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa) |
| | pntA | NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (510 aa) |
| | tppB | Tripeptide permease TppB; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily. (500 aa) |
| | btuC | Vitamin B12 import system permease protein btuC; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (326 aa) |
| | ACD08138.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (217 aa) |
| | sppA | Protease 4; Identified by match to protein family HMM PF01343; match to protein family HMM TIGR00705; match to protein family HMM TIGR00706. (618 aa) |
| | manX | PTS system, mannose-specific IIAB component; Identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854. (323 aa) |
| | manY | PTS system, mannose-specific IIC component; Identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822. (266 aa) |
| | manZ | PTS system, mannose-specific IID component; Identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828. (283 aa) |
| | ACD07287.1 | Integral membrane protein, PqiA family; Identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155. (427 aa) |
| | ACD09085.1 | Identified by match to protein family HMM PF02470. (879 aa) |
| | malF | Maltose/maltodextrin ABC transporter, permease protein MalF; Identified by match to protein family HMM PF00528. (429 aa) |
| | lolC | Lipoprotein-releasing system transmembrane protein LolC; Identified by match to protein family HMM PF02687; match to protein family HMM TIGR02212. (399 aa) |
| | ptsG | PTS system, glucose-specific IIBC component; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02002. (477 aa) |
| | mdoH | Glucans biosynthesis glucosyltransferase H; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (847 aa) |
| | putP | Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (502 aa) |
| | hyaC | Ni/Fe-hydrogenase 1 B-type cytochrome subunit HyaC; Identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125. (235 aa) |
| | pqiA | Identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155. (417 aa) |
| | ACD06894.1 | Putative formate transporter FocA; Identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790. (285 aa) |
| | ftsK | DNA translocase FtsK; Identified by match to protein family HMM PF01580; match to protein family HMM PF09397. (1310 aa) |
| | cydD | ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR02857. (588 aa) |
| | cudC | ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR02868. (573 aa) |
| | macB | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa) |
| | aqpZ | Aquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family. (231 aa) |
| | ACD08547.1 | ABC-2 type transporter, permease protein; Identified by match to protein family HMM PF01061. (377 aa) |
| | ACD09500.1 | ABC-2 type transporter, permease protein; Identified by match to protein family HMM PF01061. (368 aa) |
| | ACD10063.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF05957. (101 aa) |
| | nuoN | NADH-quinone oxidoreductase, N subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa) |
| | nuoM | NADH-quinone oxidoreductase, M subunit; Identified by match to protein family HMM PF00361; match to protein family HMM TIGR01972. (509 aa) |
| | nuoL | NADH-quinone oxidoreductase, L subunit; Identified by match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974. (613 aa) |
| | nuoK | NADH-quinone oxidoreductase, K subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa) |
| | nuoJ | NADH-quinone oxidoreductase, J subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa) |
| | nuoH | NADH-quinone oxidoreductase, H subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa) |
| | nuoA | NADH-quinone oxidoreductase, A subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa) |
| | emrK | Drug resistance MFS transporter, membrane fusion protein (MFP) subunit EmrK; Identified by similarity to SP:P52599; match to protein family HMM PF00529; match to protein family HMM TIGR00998. (387 aa) |
| | nupC | Nucleoside transporter NupC; Identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (400 aa) |
| | cysZ | CysZ protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (253 aa) |
| | uraA | Uracil permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801. (429 aa) |
| | ACD07024.1 | Conserved hypothetical protein. (206 aa) |
| | rodZ | Helix-turn-helix DNA-binding domain protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. (337 aa) |
| | yhfB | HAD hydrolase YhfB; Identified by match to protein family HMM TIGR01545. (211 aa) |
| | lepB | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. (324 aa) |
| | ACD09327.1 | Translocator protein, LysE family; Identified by match to protein family HMM PF01810. (195 aa) |
| | araE | Arabinose-proton symporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (472 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (291 aa) |
| | emrA | Identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998. (390 aa) |
| | ACD09862.1 | Conserved hypothetical protein. (111 aa) |
| | proW | Glycine betaine/L-proline ABC transporter, permease protein; Identified by match to protein family HMM PF00528. (354 aa) |
| | ACD08476.1 | Putative inner membrane protein; Identified by similarity to SP:P55734; match to protein family HMM PF00581. (174 aa) |
| | ACD07544.1 | Conserved hypothetical protein; Identified by match to protein family HMM TIGR02099. (1266 aa) |
| | ACD09209.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF07254. (135 aa) |
| | ACD07895.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF04402. (246 aa) |
| | mscS | Small-conductance mechanosensitive channel; Identified by similarity to SP:P0C0S3; match to protein family HMM PF00924; match to protein family HMM PF05552. (286 aa) |
| | exbD | TonB system transport protein ExbD; Identified by match to protein family HMM PF02472; match to protein family HMM TIGR02803. (141 aa) |
| | ACD08552.1 | Putative membrane protein; Identified by match to protein family HMM PF09335. (219 aa) |
| | bacA | Undecaprenyl-diphosphatase BacA; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (273 aa) |
| | lptC | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa) |
| | ACD09424.1 | Toluene ABC transporter, permease protein; yrbE; identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056. (260 aa) |
| | ACD08791.1 | Mce family protein; Identified by match to protein family HMM PF02470. (183 aa) |
| | mscL | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (136 aa) |
| | tsgA | Major facilitator family transporter TsgA; Identified by match to protein family HMM PF07690. (393 aa) |
| | envZ | Osmolarity sensor protein EnvZ; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (450 aa) |
| | glpG | Peptidase, S54 (rhomboid) family; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. (276 aa) |
| | dtpB | Amino acid/peptide transporter; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily. (489 aa) |
| | mtlA | PTS system, mannitol-specific IIABC component; Identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851. (637 aa) |
| | yicE | Xanthine permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801. (463 aa) |
| | pstC | Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (319 aa) |
| | emrD | Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00880. (394 aa) |
| | uhpC | Regulatory protein UhpC; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00881. (439 aa) |
| | tatA | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (89 aa) |
| | tatB | Twin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (171 aa) |
| | trkH | Trk system potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (483 aa) |
| | cpxA | Sensor histidine kinase CpxA; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (457 aa) |
| | ftsN | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (319 aa) |
| | ACD08577.1 | PTS system, mannose/fructose/sorbose family, IID component; Identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828. (384 aa) |
| | ACD10418.1 | Sorbose-permease PTS system IIC component; Identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822. (269 aa) |
| | ACD08271.1 | PTS system, mannose/fructose/sorbose family, IIA component; Identified by match to protein family HMM PF03610; match to protein family HMM TIGR00824. (135 aa) |
| | ACD08735.1 | ShiF protein; Identified by match to protein family HMM PF07690. (397 aa) |
| | frdD | Fumarate reductase, D subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa) |
| | hflK | HflK protein; HflC and HflK could encode or regulate a protease. (419 aa) |
| | hflC | HflC protein; HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda. HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins. (334 aa) |
