(17 nodes) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain network (Shigella boydii)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	arcB	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229. (778 aa)
	envZ	Osmolarity sensor protein EnvZ; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (450 aa)
	glnL	Nitrogen regulation protein NR(II); Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518. (349 aa)
	cpxA	Sensor histidine kinase CpxA; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (457 aa)
	phoR	Phosphate regulon sensor protein PhoR; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; match to protein family HMM TIGR02966. (431 aa)
	kdpD	Sensor protein KdpD; Identified by match to protein family HMM PF00512; match to protein family HMM PF00582; match to protein family HMM PF02518; match to protein family HMM PF02702. (894 aa)
	rcsC	Sensor histidine kinase/response regulator RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (949 aa)
	ACD09349.1	Heavy metal sensor histidine kinase; Member of a two-component regulatory system. (452 aa)
	baeS	Sensor histidine kinase BaeS; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (467 aa)
	rstB	Sensor histidine kinase RstB; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (433 aa)
	torS	Sensor histidine kinase/response regulator TorS; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR02956. (914 aa)
	evgS	Sensor histidine kinase/response regulator EvgS; Identified by similarity to SP:P30855; match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518. (1197 aa)
	ACD08297.1	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (475 aa)
	barA	Sensor histidine kinase/response regulator BarA; Identified by similarity to SP:P0AEC5; match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518. (918 aa)
	qseC	Sensor histidine kinase QseC; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (449 aa)
	zraS	Sensor histidine kinase ZraS; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518. (458 aa)
	creC	Sensor protein CreC; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (474 aa)

Your Current Organism:

Shigella boydii

NCBI taxonomy Id: 344609
Other names: S. boydii CDC 3083-94, Shigella boydii BS512, Shigella boydii CDC 3083-94, Shigella boydii str. CDC 3083-94, Shigella boydii strain CDC 3083-94

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACD08297.1	arcB	SbBS512_E2921	SbBS512_E3560	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	0.877
ACD08297.1	barA	SbBS512_E2921	SbBS512_E3087	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	Sensor histidine kinase/response regulator BarA; Identified by similarity to SP:P0AEC5; match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518.	0.731
ACD08297.1	evgS	SbBS512_E2921	SbBS512_E2739	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	Sensor histidine kinase/response regulator EvgS; Identified by similarity to SP:P30855; match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518.	0.678
ACD08297.1	torS	SbBS512_E2921	SbBS512_E2321	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	Sensor histidine kinase/response regulator TorS; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR02956.	0.669
ACD09349.1	arcB	SbBS512_E0915	SbBS512_E3560	Heavy metal sensor histidine kinase; Member of a two-component regulatory system.	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	0.623
ACD09349.1	barA	SbBS512_E0915	SbBS512_E3087	Heavy metal sensor histidine kinase; Member of a two-component regulatory system.	Sensor histidine kinase/response regulator BarA; Identified by similarity to SP:P0AEC5; match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518.	0.624
ACD09349.1	evgS	SbBS512_E0915	SbBS512_E2739	Heavy metal sensor histidine kinase; Member of a two-component regulatory system.	Sensor histidine kinase/response regulator EvgS; Identified by similarity to SP:P30855; match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518.	0.556
ACD09349.1	torS	SbBS512_E0915	SbBS512_E2321	Heavy metal sensor histidine kinase; Member of a two-component regulatory system.	Sensor histidine kinase/response regulator TorS; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR02956.	0.865
arcB	ACD08297.1	SbBS512_E3560	SbBS512_E2921	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.877
arcB	ACD09349.1	SbBS512_E3560	SbBS512_E0915	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Heavy metal sensor histidine kinase; Member of a two-component regulatory system.	0.623
arcB	baeS	SbBS512_E3560	SbBS512_E1155	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor histidine kinase BaeS; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.587
arcB	barA	SbBS512_E3560	SbBS512_E3087	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor histidine kinase/response regulator BarA; Identified by similarity to SP:P0AEC5; match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518.	0.986
arcB	cpxA	SbBS512_E3560	SbBS512_E4391	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor histidine kinase CpxA; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.902
arcB	creC	SbBS512_E3560	SbBS512_E4947	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor protein CreC; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.874
arcB	envZ	SbBS512_E3560	SbBS512_E3783	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Osmolarity sensor protein EnvZ; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.903
arcB	evgS	SbBS512_E3560	SbBS512_E2739	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor histidine kinase/response regulator EvgS; Identified by similarity to SP:P30855; match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518.	0.983
arcB	glnL	SbBS512_E3560	SbBS512_E4345	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Nitrogen regulation protein NR(II); Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518.	0.615
arcB	kdpD	SbBS512_E3560	SbBS512_E0554	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor protein KdpD; Identified by match to protein family HMM PF00512; match to protein family HMM PF00582; match to protein family HMM PF02518; match to protein family HMM PF02702.	0.591
arcB	phoR	SbBS512_E3560	SbBS512_E0319	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Phosphate regulon sensor protein PhoR; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; match to protein family HMM TIGR02966.	0.626
arcB	qseC	SbBS512_E3560	SbBS512_E3460	Aerobic respiration control sensor protein ArcB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.	Sensor histidine kinase QseC; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.878

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