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| | bioD2 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (231 aa) |
| | ACD10372.1 | Inner membrane ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF05992; match to protein family HMM PF06472. (561 aa) |
| | ACD08157.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (328 aa) |
| | ACD08966.1 | Putative ABC transport system ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (308 aa) |
| | hrpA | ATP-dependent helicase HrpA; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967. (1300 aa) |
| | sitB_2 | Iron/manganese transport system inner membrane protein SitB; Identified by match to protein family HMM PF00005. (275 aa) |
| | dbpA | ATP-independent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (457 aa) |
| | tyrR | Transcriptional regulatory protein TyrR; Identified by match to protein family HMM PF00158; match to protein family HMM PF01842. (513 aa) |
| | pspF | Sigma-54 dependent transcriptional regulator PspF; Identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM TIGR02974. (325 aa) |
| | sapD | Peptide ABC transporter, ATP-binding protein SapD; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (330 aa) |
| | sapF | Peptide ABC transporter, ATP-binding protein SapF; Identified by match to protein family HMM PF00005. (268 aa) |
| | ACD07866.1 | DNA replication protein dnaC homolog; Identified by match to protein family HMM PF01695. (248 aa) |
| | oppF | Oligopeptide ABC transporter, ATP-binding protein OppF; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (334 aa) |
| | oppD | Oligopeptide ABC transporter, ATP-binding protein OppD; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (337 aa) |
| | tdk | Thymidine kinase; Identified by match to protein family HMM PF00265. (205 aa) |
| | engD | GTP-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa) |
| | dhaR | PTS-dependent dihydroxyacetone kinase operon regulatory protein, DhaR; Identified by match to protein family HMM PF00158; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02954. (639 aa) |
| | minD | Septum site-determining protein MinD; Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968. (270 aa) |
| | potA | Spermidine/putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa) |
| | ACD08087.1 | Phage terminase large subunit (GpA); Identified by match to protein family HMM PF05876. (642 aa) |
| | ACD10000.1 | Putative replication protein DnaC. (276 aa) |
| | wzc | Tyrosine-protein kinase wzc; Identified by match to protein family HMM PF02706; match to protein family HMM TIGR01007. (720 aa) |
| | udk | Uridine kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00235. (213 aa) |
| | yecC | Amino acid ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (250 aa) |
| | araG | L-arabinose ABC transporter, ATP-binding protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa) |
| | ACD10404.1 | Bifunctional adenosylcobalamin biosynthesis protein CobU. (51 aa) |
| | ACD06503.1 | Bifunctional adenosylcobalamin biosynthesis protein CobU; Identified by match to protein family HMM PF02283. (144 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa) |
| | znuC | High-affinity zinc uptake ABC transporter, ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa) |
| | ACD07374.1 | Putative phage terminase, large subunit; Identified by match to protein family HMM PF03354. (553 aa) |
| | ACD08323.1 | Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa) |
| | ACD08623.1 | ABC transporter, quaternary amine uptake (QAT) family, ATP-binding protein; Identified by match to protein family HMM PF00005. (308 aa) |
| | ACD06493.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (555 aa) |
| | mglA | Galactoside ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (334 aa) |
| | ACD10106.1 | Identified by match to protein family HMM PF02492; match to protein family HMM PF07683. (328 aa) |
| | ACD07448.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily. (529 aa) |
| | ACD06460.1 | Putative helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851. (586 aa) |
| | ccmA | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa) |
| | ACD10211.1 | ABC transporter ATP-binding protein; Identified by similarity to SP:P33941; match to protein family HMM PF00005; match to protein family HMM TIGR01194. (547 aa) |
| | modC | Molybdate ABC transporter, ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa) |
| | modF | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (490 aa) |
| | holA | DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144; match to protein family HMM TIGR01128. (343 aa) |
| | gltL | Glutamate/aspartate ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (241 aa) |
| | ACD08565.1 | Identified by match to protein family HMM PF02562. (346 aa) |
| | kdpD | Sensor protein KdpD; Identified by match to protein family HMM PF00512; match to protein family HMM PF00582; match to protein family HMM PF02518; match to protein family HMM PF02702. (894 aa) |
| | fepC | Ferric enterobactin ABC transporter, ATP-binding protein FepC; Identified by match to protein family HMM PF00005. (271 aa) |
| | ACD09260.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (228 aa) |
| | ACD06765.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (225 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | dnaX | DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (643 aa) |
| | ACD07559.1 | Conserved hypothetical protein. (49 aa) |
| | mdlA | Multidrug resistance, ATP-binding protein mdlA; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. (553 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction spec [...] (784 aa) |
| | clpX | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (424 aa) |
| | sbcC | Nuclease SbcCD, C subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily. (1047 aa) |
| | aroL | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (174 aa) |
| | tauB | Taurine ABC transporter, ATP-binding protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. (255 aa) |
| | metN | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa) |
| | fhuC | Ferrichrome transport ATP-binding protein FhuC; Identified by match to protein family HMM PF00005. (265 aa) |
| | hrpB | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF08482; match to protein family HMM TIGR01970. (809 aa) |
| | ACD06361.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (308 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | secA | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa) |
| | thiQ | Thiamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (232 aa) |
| | rapA | RNA polymerase associated protein RapA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa) |
| | ACD08814.1 | Galactose/methyl galactoside import ATP-binding protein MglA. (92 aa) |
| | nadR | Nicotinamide-nucleotide adenylyltransferase; Identified by match to protein family HMM PF01381; match to protein family HMM TIGR00125; match to protein family HMM TIGR01526. (410 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | dnaC | DNA replication protein DnaC. (245 aa) |
| | ACD10145.1 | Identified by match to protein family HMM PF02492; match to protein family HMM PF07683. (318 aa) |
| | ACD06572.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF05872. (500 aa) |
| | ACD06704.1 | Type III restriction enzyme, res subunit; Identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851. (1137 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (426 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa) |
| | ACD08881.1 | Putative P-loop hydrolase; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. (153 aa) |
| | rsgA | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (350 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (940 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (471 aa) |
| | zraR | Response regulator ZraR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728. (441 aa) |
| | tuf1 | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | coaA | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. (316 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa) |
| | hslU | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa) |
| | typA | GTP-binding protein TypA; Identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394. (607 aa) |
| | ntrC | Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa) |
| | engB | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (210 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B; Identified by match to protein family HMM PF03205; match to protein family HMM TIGR00176. (175 aa) |
| | recQ | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. (609 aa) |
| | uvrD | DNA helicase II; Identified by match to protein family HMM PF00580; match to protein family HMM TIGR01075. (720 aa) |
| | recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (357 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (467 aa) |
| | trmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (454 aa) |
| | pstB | Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | ACD10382.1 | Hypothetical protein; Identified by glimmer; putative. (468 aa) |
| | ACD08392.1 | ATPase, AAA family; Identified by match to protein family HMM PF01078; match to protein family HMM PF07728; match to protein family HMM TIGR00368. (506 aa) |
| | rep | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (673 aa) |
| | rhlB | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (421 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | selB | Selenocysteine-specific translation elongation factor; Identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475. (614 aa) |
| | dppF | Dipeptide ABC transporter, ATP-binding protein DppF; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (334 aa) |
| | dppD | Dipeptide ABC transporter, ATP-binding protein DppD; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (327 aa) |
| | xylG | D-xylose ABC transporter, ATP-binding protein; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (513 aa) |
| | ACD10300.1 | YhjQ protein; Identified by match to protein family HMM PF06564; match to protein family HMM TIGR03371. (250 aa) |
| | gntK | Thermoresistant gluconokinase; Identified by match to protein family HMM PF01202; match to protein family HMM TIGR01313. (175 aa) |
| | ugpC | Sn-glycerol-3-phosphate transport ATP-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa) |
| | livF | High-affinity branched-chain amino acid ABC transporter, ATP-binding protein LivF; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily. (241 aa) |
| | livG | High-affinity branched-chain amino acid ABC transporter, ATP-binding protein LivG; Identified by match to protein family HMM PF00005. (255 aa) |
| | ftsE | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (222 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (497 aa) |
| | nikD | Nickel ABC transporter, ATP-binding protein NikD; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (254 aa) |
| | nikE | Nickel ABC transporter, ATP-binding protein NikE; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (268 aa) |
| | ACD06351.1 | ABC transporter, ATP binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF01061. (911 aa) |
| | rtcR | Sigma-54 dependent transcriptional regulator RtcR; Identified by match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728. (532 aa) |
| | feoB | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (773 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | ACD09824.1 | Identified by match to protein family HMM PF00485. (289 aa) |
| | ACD08303.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (637 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (704 aa) |
| | tuf2 | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | ACD10495.1 | Amino acid ABC transporter, ATP-binding protein; yhdZ; identified by match to protein family HMM PF00005. (252 aa) |
| | deaD | Cold-shock DEAD box protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (651 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (890 aa) |
| | hflB | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (647 aa) |
| | obg | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (390 aa) |
| | ACD06852.1 | Toluene ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (269 aa) |
| | lptB | Lipopolysaccharide ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (241 aa) |
| | rapZ | Conserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (284 aa) |
| | zapE | ATPase, AFG1 family; Reduces the stability of FtsZ polymers in the presence of ATP. (375 aa) |
| | ACD07543.1 | Identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420. (326 aa) |
| | ACD07459.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (236 aa) |
| | ACD07062.1 | Conserved hypothetical protein. (237 aa) |
| | ACD06319.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (225 aa) |
| | ACD10102.1 | LAO/AO transport system ATPase; Identified by match to protein family HMM PF03308; match to protein family HMM TIGR00750. (331 aa) |
| | rbsA | D-ribose ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (187 aa) |
| | proV | Glycine betaine/L-proline ABC transporter, ATP binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186. (400 aa) |
| | recA | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa) |
| | norR | Anaerobic nitric oxide reductase transcription regulator NorR; Identified by match to protein family HMM PF00158; match to protein family HMM PF01590. (504 aa) |
| | hypB | Hydrogenase isoenzymes nickel incorporation protein HypB; Identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073. (290 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (201 aa) |
| | cysN | Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | recD | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (608 aa) |
| | recB | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1180 aa) |
| | recC | Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (1122 aa) |
| | recN | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (553 aa) |
| | ffh | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (453 aa) |
| | clpB | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa) |
| | srmB | ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (444 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | era | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa) |
| | ACD09202.1 | Sigma-54 dependent response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728. (444 aa) |
| | engA | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (490 aa) |
| | hda | DnaA family protein Hda; Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity); Belongs to the DnaA family. HdA subfamily. (248 aa) |
| | tmcA | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (671 aa) |
| | eutP | Ethanolamine utilization protein, EutP; Identified by match to protein family HMM TIGR02528; Belongs to the EutP/PduV family. (159 aa) |
| | cysA | Sulfate/thiosulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa) |
| | hisP | Histidine ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (257 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa) |
| | bioD1 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (225 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (673 aa) |
| | ACD06569.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (578 aa) |
| | rhlE | Putative ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (454 aa) |
| | dinG | Putative ATP-dependent helicase DinG; DNA-dependent ATPase and 5'-3' DNA helicase. (716 aa) |
| | glnQ | Glutamine ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (240 aa) |
| | ACD07573.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (530 aa) |
| | gsiA | Glutathione ABC transporter, ATP-binding protein GsiA; Identified by similarity to SP:P75796; match to protein family HMM PF00005; match to protein family HMM PF08352; Belongs to the ABC transporter superfamily. (623 aa) |
| | potG | Putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa) |
| | artP | Arginine ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (242 aa) |
| | ACD08411.1 | Conserved hypothetical protein. (552 aa) |
| | macB | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa) |
| | clpA | ATP-dependent Clp protease ATP-binding subunit ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. (758 aa) |
| | cudC | ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR02868. (573 aa) |
| | cydD | ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR02857. (588 aa) |
| | ftsK | DNA translocase FtsK; Identified by match to protein family HMM PF01580; match to protein family HMM PF09397. (1310 aa) |
| | ACD10168.1 | Putative DNA recombination-associated ATPase RarA; Identified by match to protein family HMM PF00004. (447 aa) |
| | cmk | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. (227 aa) |
| | msbA | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (328 aa) |
| | mukB | Chromosome partition protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1486 aa) |
| | uup | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF02463. (635 aa) |
| | ACD08396.1 | Peptidase, S16 (lon protease) family; Identified by match to protein family HMM PF05362. (586 aa) |
| | sulA | Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (169 aa) |
| | helD | Helicase IV; Identified by match to protein family HMM PF00580. (684 aa) |
| | etk1 | Tyrosine-protein kinase etk; Identified by match to protein family HMM PF02706; match to protein family HMM TIGR01007. (726 aa) |
| | phoH | Protein phoH; Identified by match to protein family HMM PF02562. (354 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | holB | DNA polymerase III, delta' subunit; Identified by match to protein family HMM PF09115; match to protein family HMM TIGR00678. (334 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1148 aa) |
| | lolD | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa) |
| | ACD09634.1 | ABC ATPase. (91 aa) |
| | ACD08912.1 | Conserved hypothetical protein. (636 aa) |
| | ACD08138.1 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (217 aa) |
| | btuD | Vitamin B12 import ATP-binding protein BtuD; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa) |
| | sufC | FeS assembly ATPase SufC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978. (248 aa) |
