(13 nodes) Biosynthesis of unsaturated fatty acids, and ELO family network (Aspergillus clavatus)

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Your Input:
	ACLA_002400	Elongation of fatty acids protein. (344 aa)
	ACLA_070510	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (345 aa)
	ACLA_009290	Uncharacterized protein. (919 aa)
	ACLA_007610	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (456 aa)
	ACLA_092690	Fatty acid desaturase, putative. (564 aa)
	ACLA_067520	Cytochrome b5-like heme/steroid binding domain protein. (372 aa)
	ACLA_049480	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (246 aa)
	ACLA_049930	Steroid alpha reductase family protein. (312 aa)
	ACLA_097340	Oleate delta-12 desaturase. (391 aa)
	ACLA_018810	Elongation of fatty acids protein. (548 aa)
	ACLA_019100	Short chain dehydrogenase/reductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (337 aa)
	ACLA_022950	Oleate delta-12 desaturase. (469 aa)
	ACLA_025320	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (426 aa)

Your Current Organism:

Aspergillus clavatus

NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLA_002400	ACLA_007610	A1C561	A1CDS5	Elongation of fatty acids protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.943
ACLA_002400	ACLA_019100	A1C561	A1CNI4	Elongation of fatty acids protein.	Short chain dehydrogenase/reductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.901
ACLA_002400	ACLA_022950	A1C561	A1CPL0	Elongation of fatty acids protein.	Oleate delta-12 desaturase.	0.900
ACLA_002400	ACLA_025320	A1C561	A1CQ94	Elongation of fatty acids protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.943
ACLA_002400	ACLA_049480	A1C561	A1CHX1	Elongation of fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.912
ACLA_002400	ACLA_049930	A1C561	A1CI16	Elongation of fatty acids protein.	Steroid alpha reductase family protein.	0.934
ACLA_002400	ACLA_067520	A1C561	A1CGN3	Elongation of fatty acids protein.	Cytochrome b5-like heme/steroid binding domain protein.	0.955
ACLA_002400	ACLA_070510	A1C561	A1C6J8	Elongation of fatty acids protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.948
ACLA_002400	ACLA_092690	A1C561	A1CFC2	Elongation of fatty acids protein.	Fatty acid desaturase, putative.	0.588
ACLA_002400	ACLA_097340	A1C561	A1CMK9	Elongation of fatty acids protein.	Oleate delta-12 desaturase.	0.900
ACLA_007610	ACLA_002400	A1CDS5	A1C561	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Elongation of fatty acids protein.	0.943
ACLA_007610	ACLA_009290	A1CDS5	A1C9U1	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Uncharacterized protein.	0.456
ACLA_007610	ACLA_018810	A1CDS5	A1CNF6	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Elongation of fatty acids protein.	0.610
ACLA_007610	ACLA_019100	A1CDS5	A1CNI4	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Short chain dehydrogenase/reductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.906
ACLA_007610	ACLA_022950	A1CDS5	A1CPL0	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Oleate delta-12 desaturase.	0.914
ACLA_007610	ACLA_025320	A1CDS5	A1CQ94	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.932
ACLA_007610	ACLA_049480	A1CDS5	A1CHX1	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.902
ACLA_007610	ACLA_049930	A1CDS5	A1CI16	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Steroid alpha reductase family protein.	0.920
ACLA_007610	ACLA_067520	A1CDS5	A1CGN3	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Cytochrome b5-like heme/steroid binding domain protein.	0.933
ACLA_007610	ACLA_070510	A1CDS5	A1C6J8	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.932