(70 nodes) Glycolysis, and Pentose phosphate pathway network (Aspergillus clavatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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	ACLA_057400	Glucosamine-6-phosphate isomerase. (366 aa)
	ACLA_057430	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (430 aa)
	ACLA_002630	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (387 aa)
	ACLA_003290	Glyceraldehyde-3-phosphate dehydrogenase. (359 aa)
	ACLA_004210	Glyceraldehyde-3-phosphate dehydrogenase. (360 aa)
	ACLA_068420	Phosphotransferase. (490 aa)
	ACLA_068850	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	mpdA	Mannitol-1-phosphate 5-dehydrogenase; Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway. (388 aa)
	ACLA_069990	Triosephosphate isomerase. (290 aa)
	ACLA_070000	Ribose/galactose isomerase, putative. (162 aa)
	ACLA_070560	Alpha-glucosidase/alpha-amylase, putative. (608 aa)
	ACLA_073460	Endo-arabinanase, putative; Belongs to the glycosyl hydrolase 43 family. (435 aa)
	ACLA_074170	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (250 aa)
	ACLA_043170	Glyceraldehyde-3-phosphate dehydrogenase, putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (357 aa)
	ACLA_054960	Phosphoglycerate mutase family protein. (273 aa)
	ACLA_011340	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
	ACLA_012260	MutT/nudix family protein; Belongs to the Nudix hydrolase family. (207 aa)
	ACLA_012270	NUDIX family hydrolase, putative. (306 aa)
	ACLA_013360	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (291 aa)
	ACLA_016430	Triosephosphate isomerase. (249 aa)
	ACLA_017070	Uncharacterized protein. (260 aa)
	ACLA_061500	Phosphoglucomutase, putative. (543 aa)
	ACLA_064080	Phosphoketolase, putative. (811 aa)
	ACLA_064170	Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
	ACLA_005730	Phosphotransferase. (548 aa)
	ACLA_007390	Ribose phosphate diphosphokinase Prs1, putative. (489 aa)
	ACLA_007490	Fructose-2,6-bisphosphatase. (453 aa)
	ACLA_007510	Phosphoglycerate mutase family protein. (290 aa)
	ACLA_088110	Glucosamine-fructose-6-phosphate aminotransferase. (694 aa)
	ACLA_088360	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (269 aa)
	ACLA_088550	Enolase/allergen Asp F 22. (438 aa)
	ACLA_092700	Phosphoglucomutase. (602 aa)
	ACLA_094550	Beta-fructofuranosidase, putative; Belongs to the glycosyl hydrolase 32 family. (513 aa)
	ACLA_047790	Mannose-6-phosphate isomerase, class I. (403 aa)
	ACLA_049960	Phosphoribosyl diphosphate synthase isoform 4. (320 aa)
	ACLA_050400	Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (355 aa)
	ACLA_050590	Mannose-1-phosphate guanylyltransferase. (375 aa)
	ACLA_051060	Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (232 aa)
	ACLA_051120	TPR domain protein. (400 aa)
	ACLA_034540	Deoxyribose-phosphate aldolase. (265 aa)
	ACLA_036450	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (504 aa)
	ACLA_037220	Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent. (520 aa)
	ACLA_038690	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase, putative. (806 aa)
	ACLA_039570	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
	ACLA_041080	Ribose-phosphate pyrophosphokinase. (442 aa)
	abnA	Probable arabinan endo-1,5-alpha-L-arabinosidase A; Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity); Belongs to the glycosyl hydrolase 43 family. (321 aa)
	ACLA_078110	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (792 aa)
	ACLA_095440	6-phosphofructo-2-kinase, putative. (534 aa)
	ACLA_096650	Phosphotransferase. (474 aa)
	ACLA_097870	Phosphoglycerate mutase family protein. (242 aa)
	ACLA_098010	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (195 aa)
	ACLA_098220	Phosphotransferase. (492 aa)
	abnC	Probable arabinan endo-1,5-alpha-L-arabinosidase C; Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity); Belongs to the glycosyl hydrolase 43 family. (319 aa)
	ACLA_099280	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (351 aa)
	ACLA_018000	Glucokinase regulator family protein, putative. (655 aa)
	ACLA_020000	Uncharacterized protein. (415 aa)
	ACLA_021060	2-deoxy-D-gluconate 3-dehydrogenase, putative. (265 aa)
	ACLA_021930	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (684 aa)
	ACLA_022150	Mannose-6-phosphate isomerase. (457 aa)
	ACLA_025200	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
	ACLA_027360	6-phosphofructo-2-kinase 1. (709 aa)
	ACLA_028270	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (544 aa)
	ACLA_031450	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (266 aa)
	ACLA_081610	Pyruvate kinase; Belongs to the pyruvate kinase family. (526 aa)
	ACLA_081780	GDP-mannose pyrophosphorylase A. (437 aa)
	ACLA_081870	Phosphoenolpyruvate carboxykinase AcuF. (601 aa)
	ACLA_082170	Phosphoglycerate mutase family protein. (256 aa)
	ACLA_082590	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (508 aa)
	ACLA_083680	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (517 aa)
	ACLA_084340	Ribose 5-phosphate isomerase A. (272 aa)

Your Current Organism:

Aspergillus clavatus

NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLA_002630	ACLA_007390	A1C584	A1CDQ3	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Ribose phosphate diphosphokinase Prs1, putative.	0.917
ACLA_002630	ACLA_011340	A1C584	A1CAD9	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.461
ACLA_002630	ACLA_013360	A1C584	A1CAY3	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.525
ACLA_002630	ACLA_020000	A1C584	A1CNS4	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Uncharacterized protein.	0.525
ACLA_002630	ACLA_021930	A1C584	A1CPA8	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.929
ACLA_002630	ACLA_034540	A1C584	A1CJC7	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Deoxyribose-phosphate aldolase.	0.936
ACLA_002630	ACLA_039570	A1C584	A1CKR8	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.479
ACLA_002630	ACLA_041080	A1C584	A1CL68	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Ribose-phosphate pyrophosphokinase.	0.917
ACLA_002630	ACLA_049960	A1C584	A1CI19	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Phosphoribosyl diphosphate synthase isoform 4.	0.917
ACLA_002630	ACLA_068850	A1C584	A1C636	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.573
ACLA_002630	ACLA_070000	A1C584	A1C6E8	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Ribose/galactose isomerase, putative.	0.921
ACLA_002630	ACLA_078110	A1C584	A1CLT4	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.466
ACLA_002630	ACLA_084340	A1C584	A1CTV2	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Ribose 5-phosphate isomerase A.	0.934
ACLA_002630	ACLA_092700	A1C584	A1CFC3	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Phosphoglucomutase.	0.930
ACLA_002630	ACLA_094550	A1C584	A1CFV6	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Beta-fructofuranosidase, putative; Belongs to the glycosyl hydrolase 32 family.	0.588
ACLA_002630	ACLA_099280	A1C584	A1CN46	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.906
ACLA_003290	ACLA_005730	A1C5E9	A1CD90	Glyceraldehyde-3-phosphate dehydrogenase.	Phosphotransferase.	0.623
ACLA_003290	ACLA_007510	A1C5E9	A1CDR5	Glyceraldehyde-3-phosphate dehydrogenase.	Phosphoglycerate mutase family protein.	0.496
ACLA_003290	ACLA_011340	A1C5E9	A1CAD9	Glyceraldehyde-3-phosphate dehydrogenase.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.966
ACLA_003290	ACLA_013360	A1C5E9	A1CAY3	Glyceraldehyde-3-phosphate dehydrogenase.	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.972