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LSM1 LSM1 ACLA_070740 ACLA_070740 ACLA_002030 ACLA_002030 ACLA_058960 ACLA_058960 ACLA_058730 ACLA_058730 ACLA_038100 ACLA_038100 ACLA_023090 ACLA_023090 ACLA_023580 ACLA_023580 ACLA_024250 ACLA_024250 ACLA_027490 ACLA_027490 ACLA_029650 ACLA_029650 ACLA_030940 ACLA_030940 ACLA_015480 ACLA_015480 ACLA_016350 ACLA_016350 lsm6 lsm6 ACLA_089120 ACLA_089120 ACLA_065340 ACLA_065340 ACLA_015620 ACLA_015620 ACLA_051380 ACLA_051380 ccr4 ccr4 dhh1 dhh1 ACLA_035980 ACLA_035980 ACLA_038080 ACLA_038080 ACLA_013770 ACLA_013770 ACLA_012650 ACLA_012650 ACLA_010640 ACLA_010640 ACLA_054620 ACLA_054620 ACLA_074190 ACLA_074190 LSM4 LSM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LSM1U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (177 aa)
ACLA_070740Uncharacterized protein. (292 aa)
ACLA_0020305'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1408 aa)
ACLA_058960Uncharacterized protein. (370 aa)
ACLA_058730RNA polymerase II subunit 7. (169 aa)
ACLA_038100Ccr4-Not transcription complex subunit (NOT1), putative. (2346 aa)
ACLA_023090G2/M phase checkpoint control protein Sum2, putative. (574 aa)
ACLA_023580Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1. (480 aa)
ACLA_024250Cell wall biogenesis protein phosphatase Ssd1, putative. (1316 aa)
ACLA_027490Uncharacterized protein. (1524 aa)
ACLA_029650SAM domain protein. (613 aa)
ACLA_030940Acid phosphatase, putative. (358 aa)
ACLA_015480Decapping enzyme Dcp2, putative. (856 aa)
ACLA_016350YjeF_N domain protein. (705 aa)
lsm6U6 snRNA-associated Sm-like protein LSm6; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2- LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 [...] (78 aa)
ACLA_089120mRNA decapping hydrolase, putative. (328 aa)
ACLA_065340Zinc knuckle domain protein. (236 aa)
ACLA_015620U6 small nuclear ribonucleoprotein (Lsm3), putative. (74 aa)
ACLA_051380Cell differentiation protein (Rcd1), putative. (406 aa)
ccr4Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (667 aa)
dhh1ATP-dependent RNA helicase dhh1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (503 aa)
ACLA_035980Polymerase (RNA) II (DNA directed) polypeptide D. (148 aa)
ACLA_038080Tubulin-tyrosine ligase family protein. (772 aa)
ACLA_013770Topisomerase II associated protein (Pat1), putative. (826 aa)
ACLA_012650Decapping enzyme Dcp1, putative. (331 aa)
ACLA_010640CCR4-NOT core complex subunit Caf1, putative. (507 aa)
ACLA_054620Uncharacterized protein. (297 aa)
ACLA_074190U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (119 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
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