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ACLA_014550 ACLA_014550 ACLA_014650 ACLA_014650 ACLA_060570 ACLA_060570 ACLA_061950 ACLA_061950 ACLA_005400 ACLA_005400 ACLA_005560 ACLA_005560 ACLA_087400 ACLA_087400 ACLA_086380 ACLA_086380 ACLA_083910 ACLA_083910 ACLA_083810 ACLA_083810 ACLA_080350 ACLA_080350 ACLA_080290 ACLA_080290 ACLA_080060 ACLA_080060 ACLA_080030 ACLA_080030 ACLA_031570 ACLA_031570 ACLA_030150 ACLA_030150 ACLA_030120 ACLA_030120 ACLA_029480 ACLA_029480 ACLA_028180 ACLA_028180 ACLA_027100 ACLA_027100 ACLA_027040 ACLA_027040 ACLA_026290 ACLA_026290 ACLA_026140 ACLA_026140 ACLA_023760 ACLA_023760 ACLA_021550 ACLA_021550 ACLA_021440 ACLA_021440 ACLA_021310 ACLA_021310 ACLA_020830 ACLA_020830 ACLA_020720 ACLA_020720 ACLA_020630 ACLA_020630 ACLA_019940 ACLA_019940 ACLA_018680 ACLA_018680 ACLA_098480 ACLA_098480 sub2 sub2 ACLA_095490 ACLA_095490 ACLA_042010 ACLA_042010 ACLA_041900 ACLA_041900 ACLA_039700 ACLA_039700 ACLA_038510 ACLA_038510 rtt106 rtt106 ACLA_090780 ACLA_090780 ACLA_092960 ACLA_092960 ACLA_064940 ACLA_064940 ACLA_065630 ACLA_065630 ACLA_050750 ACLA_050750 ACLA_051000 ACLA_051000 ACLA_051570 ACLA_051570 ccr4 ccr4 ACLA_052110 ACLA_052110 ACLA_052440 ACLA_052440 ACLA_033570 ACLA_033570 ACLA_033860 ACLA_033860 ACLA_033890 ACLA_033890 ACLA_034050 ACLA_034050 ACLA_035020 ACLA_035020 ACLA_035630 ACLA_035630 ACLA_035980 ACLA_035980 ACLA_036000 ACLA_036000 ACLA_037570 ACLA_037570 ACLA_037980 ACLA_037980 ACLA_058350 ACLA_058350 ACLA_058730 ACLA_058730 ACLA_058910 ACLA_058910 ACLA_000540 ACLA_000540 ACLA_000660 ACLA_000660 ACLA_000810 ACLA_000810 ACLA_000920 ACLA_000920 ACLA_001500 ACLA_001500 ACLA_001520 ACLA_001520 ACLA_001850 ACLA_001850 ACLA_001990 ACLA_001990 ACLA_003930 ACLA_003930 ACLA_069140 ACLA_069140 dbp2 dbp2 ACLA_069970 ACLA_069970 ACLA_070150 ACLA_070150 ACLA_071910 ACLA_071910 ACLA_072600 ACLA_072600 ACLA_072610 ACLA_072610 ACLA_073350 ACLA_073350 ACLA_074620 ACLA_074620 ACLA_074630 ACLA_074630 ACLA_054040 ACLA_054040 ACLA_055070 ACLA_055070 ACLA_008810 ACLA_008810 ACLA_009130 ACLA_009130 ino80 ino80 ACLA_010290 ACLA_010290 ACLA_014170 ACLA_014170 ACLA_010440 ACLA_010440 ACLA_014220 ACLA_014220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_014550Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (286 aa)
ACLA_014650Transcription factor TFIIH subunit Tfb4, putative. (386 aa)
ACLA_060570Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (717 aa)
ACLA_061950CBF/NF-Y family transcription factor, putative. (142 aa)
ACLA_005400Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily. (404 aa)
ACLA_005560DNA-directed RNA polymerase II subunit RPB11a, putative. (165 aa)
ACLA_087400Uncharacterized protein. (639 aa)
ACLA_086380Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (294 aa)
ACLA_083910AAA_12 domain-containing protein. (94 aa)
ACLA_083810Transcription factor TFIID complex 145 kDa subunit, putative. (1113 aa)
ACLA_080350DNA directed RNA polymerase II 15 kDa subunit, putative. (122 aa)
ACLA_080290Transcription factor TFIIE complex alpha subunit, putative. (452 aa)
ACLA_080060Uncharacterized protein. (336 aa)
ACLA_080030RNA polymerase II transcription factor SIII (Elongin) subunit A, putative. (389 aa)
ACLA_031570Transcription initiation factor TFIID subunit, putative. (744 aa)
ACLA_030150PCI domain protein. (455 aa)
ACLA_030120HMG box protein, putative. (305 aa)
ACLA_029480DNA-directed RNA polymerase I, II, and III subunit Rpb6. (161 aa)
ACLA_028180Nuclear localization protein NPL6, putative. (586 aa)
ACLA_027100mRNA cleavage factor complex component Pcf11, putative. (652 aa)
ACLA_027040MYB DNA-binding domain protein. (292 aa)
ACLA_026290Uncharacterized protein. (468 aa)
ACLA_026140Transcription initiation factor TFIID subunit 13, putative. (170 aa)
ACLA_023760DUF4211 domain-containing protein. (463 aa)
ACLA_021550TFIIH complex helicase Rad3, putative. (771 aa)
ACLA_021440SAGA-like transcriptional regulatory complex subunit Spt3, putative. (326 aa)
ACLA_021310RNA polymerase subunit. (234 aa)
ACLA_020830Transcription initiation factor TFIID, 31kD subunit, putative. (313 aa)
ACLA_020720DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1765 aa)
ACLA_020630Transcription factor TFIIA complex subunit Toa1, putative. (402 aa)
ACLA_019940DUF1014 domain protein. (222 aa)
ACLA_018680Cleavage and polyadenylation specifity factor, 73 kDa subunit, putative. (878 aa)
ACLA_098480tRNA-splicing endonuclease, putative. (2137 aa)
sub2ATP-dependent RNA helicase sub2; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (441 aa)
ACLA_095490HLA class III protein Dom3z. (356 aa)
ACLA_042010DNA repair protein Rex1, putative. (72 aa)
ACLA_041900Bromodomain associated protein. (348 aa)
ACLA_039700Uncharacterized protein. (592 aa)
ACLA_038510Transcription initiation protein. (350 aa)
rtt106Histone chaperone rtt106; Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity). (463 aa)
ACLA_090780Exosome complex endonuclease 1/ribosomal RNA processing protein, putative. (269 aa)
ACLA_092960RNA polymerase II transcription elongation factor Rtf1p, putative. (605 aa)
ACLA_064940DNA-directed RNA polymerases N/8 kDa subunit superfamily. (74 aa)
ACLA_065630DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1257 aa)
ACLA_050750RNA polymerase II transcription factor, putative. (644 aa)
ACLA_051000Metallothionein-I gene transcription activator. (76 aa)
ACLA_051570Fungal specific transcription factor domain protein. (628 aa)
ccr4Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (667 aa)
ACLA_052110Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (767 aa)
ACLA_052440SNF2 family helicase/ATPase, putative. (1121 aa)
ACLA_033570RSC complex subunit (RSC1), putative. (891 aa)
ACLA_033860Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1421 aa)
ACLA_033890Transcription factor Rba50, putative. (483 aa)
ACLA_034050Transcription initiation factor TFIID subunit 12, putative. (630 aa)
ACLA_035020Myb-like DNA-binding protein, putative. (909 aa)
ACLA_035630Transcription elongation factor S-II. (304 aa)
ACLA_035980Polymerase (RNA) II (DNA directed) polypeptide D. (148 aa)
ACLA_036000C6 transcription factor (OTam), putative. (663 aa)
ACLA_037570RNA-binding protein (Nab3), putative. (898 aa)
ACLA_037980RNA polymerase I and III transcription factor complex component Tbp, putative. (273 aa)
ACLA_058350Uncharacterized protein. (1269 aa)
ACLA_058730RNA polymerase II subunit 7. (169 aa)
ACLA_058910Transcription initiation factor iif, beta subunit. (374 aa)
ACLA_000540RNase3 domain protein. (228 aa)
ACLA_000660Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (135 aa)
ACLA_000810General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (456 aa)
ACLA_000920RNA binding protein Nrd1, putative. (741 aa)
ACLA_001500Transcription initiation factor TFIID complex 60 kDa subunit. (448 aa)
ACLA_001520Transcription initiation factor TFIID subunit beta, putative. (521 aa)
ACLA_001850TFIIH complex helicase Ssl2, putative. (823 aa)
ACLA_001990Protein kinase, putative. (1072 aa)
ACLA_003930Copper fist DNA binding domain protein. (92 aa)
ACLA_069140Uncharacterized protein. (340 aa)
dbp2ATP-dependent RNA helicase dbp2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing. (549 aa)
ACLA_069970Uncharacterized protein. (560 aa)
ACLA_070150Pol II transcription elongation factor subunit Cdc73, putative. (482 aa)
ACLA_071910RNA polymerase II subunit 3. (333 aa)
ACLA_072600Bromodomain associated protein. (215 aa)
ACLA_072610Transcription initiation factor TFIID subunit 7, putative. (484 aa)
ACLA_073350Histone-like transcription factor (CBF/NF-Y), putative. (246 aa)
ACLA_074620Uncharacterized protein. (360 aa)
ACLA_074630Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
ACLA_054040Nuclear matrix protein. (669 aa)
ACLA_055070HLH DNA binding domain protein, putative. (296 aa)
ACLA_008810Protein kinase domain protein. (552 aa)
ACLA_009130RNA polymerase II transcription elongation factor (Ctr9), putative. (1229 aa)
ino80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1707 aa)
ACLA_010290Cyclin Ccl1, putative; Belongs to the cyclin family. (440 aa)
ACLA_014170DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (145 aa)
ACLA_010440Nucleoside-diphosphate-sugar epimerase, putative. (2450 aa)
ACLA_014220Nucleosome remodeling complex ATPase subunit (Snf2h), putative. (657 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
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