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ACLA_013860 ACLA_013860 ACLA_012950 ACLA_012950 ACLA_012730 ACLA_012730 ACLA_012060 ACLA_012060 ACLA_011590 ACLA_011590 ACLA_054780 ACLA_054780 ACLA_054430 ACLA_054430 ACLA_043840 ACLA_043840 ACLA_043620 ACLA_043620 ACLA_073750 ACLA_073750 ACLA_073670 ACLA_073670 ACLA_072910 ACLA_072910 ACLA_057330 ACLA_057330 ACLA_059610 ACLA_059610 ACLA_060090 ACLA_060090 ACLA_003850 ACLA_003850 ACLA_003950 ACLA_003950 ACLA_067970 ACLA_067970 ACLA_069640 ACLA_069640 ACLA_070440 ACLA_070440 ACLA_070500 ACLA_070500 ACLA_071390 ACLA_071390 ACLA_072440 ACLA_072440 ACLA_053310 ACLA_053310 ACLA_053300 ACLA_053300 ACLA_052080 ACLA_052080 ACLA_050580 ACLA_050580 ACLA_047150 ACLA_047150 ACLA_047000 ACLA_047000 ACLA_046440 ACLA_046440 ACLA_046180 ACLA_046180 ACLA_066340 ACLA_066340 ACLA_094470 ACLA_094470 ACLA_093110 ACLA_093110 atg26 atg26 ACLA_090820 ACLA_090820 ACLA_089950 ACLA_089950 ACLA_008020 ACLA_008020 ACLA_005700 ACLA_005700 ACLA_005420 ACLA_005420 ACLA_061330 ACLA_061330 ACLA_061020 ACLA_061020 ACLA_061010 ACLA_061010 ACLA_061000 ACLA_061000 ACLA_017250 ACLA_017250 ACLA_013850 ACLA_013850 ACLA_087410 ACLA_087410 cprA cprA ACLA_081520 ACLA_081520 ACLA_080210 ACLA_080210 ACLA_079720 ACLA_079720 ACLA_030640 ACLA_030640 mcr1 mcr1 ACLA_029950 ACLA_029950 ACLA_028880 ACLA_028880 ACLA_028840 ACLA_028840 ACLA_028560 ACLA_028560 ACLA_027450 ACLA_027450 ACLA_024410 ACLA_024410 ACLA_020750 ACLA_020750 ACLA_020260 ACLA_020260 ACLA_018340 ACLA_018340 ACLA_099370 ACLA_099370 ACLA_099180 ACLA_099180 ACLA_098770 ACLA_098770 ACLA_095960 ACLA_095960 ACLA_095640 ACLA_095640 ACLA_095560 ACLA_095560 ACLA_095400 ACLA_095400 ACLA_078560 ACLA_078560 ACLA_038550 ACLA_038550 ACLA_033630 ACLA_033630
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_013860Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (348 aa)
ACLA_012950Alpha/beta hydrolase fold protein. (394 aa)
ACLA_012730Squalene monooxygenase Erg1. (479 aa)
ACLA_012060AMP-binding enzyme, putative. (558 aa)
ACLA_011590Triglyceride lipase-cholesterol esterase, putative. (467 aa)
ACLA_054780Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (377 aa)
ACLA_054430LysM domain protein, putative. (654 aa)
ACLA_043840Uncharacterized protein. (371 aa)
ACLA_043620C-4 methyl sterol oxidase, putative; Belongs to the sterol desaturase family. (298 aa)
ACLA_073750EBP domain protein, putative. (245 aa)
ACLA_073670Uncharacterized protein. (726 aa)
ACLA_072910Ab-hydrolase associated lipase, putative. (649 aa)
ACLA_057330Acetyl-CoA acetyltransferase, putative; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
ACLA_059610Glycosyltransferase family 28 N-terminal domain protein. (976 aa)
ACLA_0600903-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (466 aa)
ACLA_003850Uncharacterized protein. (257 aa)
ACLA_003950Cytochrome b5-like Heme/Steroid binding domain protein; Belongs to the cytochrome b5 family. (163 aa)
ACLA_067970C-4 methyl sterol oxidase (Erg25), putative; Belongs to the sterol desaturase family. (249 aa)
ACLA_069640Enoyl-CoA hydratase. (273 aa)
ACLA_070440Uncharacterized protein. (443 aa)
ACLA_070500Ergosterol biosynthesis protein Erg28, putative. (141 aa)
ACLA_071390Lipase, putative. (749 aa)
ACLA_072440C-3 sterol dehydrogenase/C-4 decarboxylase. (412 aa)
ACLA_053310C-14 sterol reductase. (477 aa)
ACLA_053300Ergosterol biosynthesis ERG4/ERG24 family protein. (319 aa)
ACLA_052080Long-chain-fatty-acid-CoA ligase, putative. (564 aa)
ACLA_0505803-ketosteroid reductase. (452 aa)
ACLA_047150Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (536 aa)
ACLA_047000INSIG domain protein. (359 aa)
ACLA_046440Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (403 aa)
ACLA_04618014-alpha sterol demethylase Cyp51A; Belongs to the cytochrome P450 family. (514 aa)
ACLA_066340Farnesyl-diphosphate farnesyltransferase, putative. (471 aa)
ACLA_094470C-4 methylsterol oxidase, putative; Belongs to the sterol desaturase family. (245 aa)
ACLA_093110Cytochrome b5-like heme/steroid binding domain protein; Belongs to the cytochrome b5 family. (81 aa)
atg26Sterol 3-beta-glucosyltransferase; Probable sterol 3-beta-glucosyltransferase that mediates autophagic degradation of peroxisomes (pexophagy) (By similarity). Also required for cytoplasm to vacuole transport (Cvt) and autophagic degradation of mitochondria (mitophagy) and nuclei (nucleophagy) (By similarity); Belongs to the glycosyltransferase 28 family. (1406 aa)
ACLA_0908203-hydroxy-3-methylglutaryl coenzyme A reductase. (1132 aa)
ACLA_089950Cytochrome b5, putative; Belongs to the cytochrome b5 family. (136 aa)
ACLA_008020Cytochrome P450; Belongs to the cytochrome P450 family. (535 aa)
ACLA_005700Uncharacterized protein. (266 aa)
ACLA_00542014-alpha sterol demethylase Cyp51B; Belongs to the cytochrome P450 family. (524 aa)
ACLA_061330Cell surface protein, putative. (197 aa)
ACLA_061020Siderophore biosynthesis acetylase AceI, putative. (450 aa)
ACLA_061010Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (271 aa)
ACLA_061000Nonribosomal peptide synthase SidD. (2066 aa)
ACLA_017250C-24(28) sterol reductase. (479 aa)
ACLA_013850Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (484 aa)
ACLA_087410FAD binding domain protein. (90 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)
ACLA_081520C-3 sterol dehydrogenase, putative. (311 aa)
ACLA_080210O-acyltransferase. (499 aa)
ACLA_079720Cytochrome b5, putative; Belongs to the cytochrome b5 family. (83 aa)
ACLA_030640Cytochrome P450 sterol C-22 desaturase, putaitve; Belongs to the cytochrome P450 family. (531 aa)
mcr1NADH-cytochrome b5 reductase 2; May mediate the reduction of outer membrane cytochrome b5. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (322 aa)
ACLA_029950C-8 sterol isomerase (Erg-1), putative. (238 aa)
ACLA_028880C-14 sterol reductase. (498 aa)
ACLA_028840Uncharacterized protein. (245 aa)
ACLA_028560O-acyltransferase. (530 aa)
ACLA_027450C-24(28) sterol reductase. (609 aa)
ACLA_024410Sterol desaturase family; Belongs to the sterol desaturase family. (339 aa)
ACLA_020750Sterol desaturase, putative; Belongs to the sterol desaturase family. (300 aa)
ACLA_020260EBP domain protein, putative. (229 aa)
ACLA_018340Long-chain-fatty-acid-CoA ligase, putative. (584 aa)
ACLA_099370DUF453 domain protein. (405 aa)
ACLA_099180Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (286 aa)
ACLA_098770Cytochrome P450, putative; Belongs to the cytochrome P450 family. (509 aa)
ACLA_095960Cytochrome P450 oxidoreductase, putative; Belongs to the cytochrome P450 family. (425 aa)
ACLA_095640Sucrose cleavage family protein. (291 aa)
ACLA_095560Cytochrome c mitochondrial import factor (Cyc2), putative. (380 aa)
ACLA_095400Sterol delta 5,6-desaturase ERG3; Belongs to the sterol desaturase family. (352 aa)
ACLA_078560Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (347 aa)
ACLA_0385503-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (460 aa)
ACLA_033630Uncharacterized protein. (369 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
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