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cfd1 cfd1 ACLA_069400 ACLA_069400 ACLA_073190 ACLA_073190 nbp35 nbp35 ACLA_076060 ACLA_076060 TAH18 TAH18 caf17 caf17 ACLA_061630 ACLA_061630 ACLA_046000 ACLA_046000 ACLA_049710 ACLA_049710 ACLA_049870 ACLA_049870 nar1 nar1 ACLA_001240 ACLA_001240 ACLA_004360 ACLA_004360 ACLA_003420 ACLA_003420 ACLA_041730 ACLA_041730 ACLA_057310 ACLA_057310 ACLA_057970 ACLA_057970 ACLA_058800 ACLA_058800 ACLA_083040 ACLA_083040 ACLA_030000 ACLA_030000 ACLA_027950 ACLA_027950 dre2 dre2 cia1 cia1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
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cfd1Cytosolic Fe-S cluster assembly factor cfd1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (315 aa)
ACLA_069400Iron-sulfur cluster assembly accessory protein Isa2, putative. (240 aa)
ACLA_073190ATP-grasp domain-containing protein. (613 aa)
nbp35Cytosolic Fe-S cluster assembly factor nbp35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (344 aa)
ACLA_076060Uncharacterized protein. (421 aa)
TAH18NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (646 aa)
caf17Putative transferase caf17, mitochondrial. (450 aa)
ACLA_061630Uncharacterized protein. (261 aa)
ACLA_046000Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (171 aa)
ACLA_049710Mitochondrial chaperone Frataxin, putative. (213 aa)
ACLA_049870Conserved membrane protein, putative. (558 aa)
nar1Cytosolic Fe-S cluster assembly factor nar1; Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity). (597 aa)
ACLA_0012402Fe-2S iron-sulfur cluster binding domain protein. (201 aa)
ACLA_004360TLDc domain-containing protein. (503 aa)
ACLA_003420ATP-grasp domain-containing protein. (722 aa)
ACLA_041730tRNA splicing protein (Spl1), putative. (517 aa)
ACLA_057310Cytoplasmic protein required for cell viability, putative. (200 aa)
ACLA_057970DnaJ domain protein. (274 aa)
ACLA_058800DNA repair/transcription protein, putative. (1057 aa)
ACLA_083040Nucleotide binding protein, putative. (324 aa)
ACLA_030000NifU-related protein. (320 aa)
ACLA_027950Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (149 aa)
dre2Fe-S cluster assembly protein dre2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35. Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18. Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (310 aa)
cia1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (453 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
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