STRINGSTRING
ACLA_057890 ACLA_057890 myoA myoA ACLA_002900 ACLA_002900 ACLA_003120 ACLA_003120 ACLA_003470 ACLA_003470 ACLA_068290 ACLA_068290 ACLA_069350 ACLA_069350 ACLA_073320 ACLA_073320 ACLA_042870 ACLA_042870 ACLA_009220 ACLA_009220 ACLA_014250 ACLA_014250 ACLA_014630 ACLA_014630 pan1 pan1 ACLA_088280 ACLA_088280 ACLA_094510 ACLA_094510 ACLA_047060 ACLA_047060 ACLA_048490 ACLA_048490 ACLA_052220 ACLA_052220 ACLA_034100 ACLA_034100 ACLA_034240 ACLA_034240 ACLA_041720 ACLA_041720 ACLA_097920 ACLA_097920 ACLA_098100 ACLA_098100 ACLA_098110 ACLA_098110 ACLA_022100 ACLA_022100 ACLA_022440 ACLA_022440 end3 end3 ACLA_022710 ACLA_022710 ACLA_023960 ACLA_023960 ACLA_025980 ACLA_025980 ACLA_031550 ACLA_031550 ACLA_031870 ACLA_031870 ACLA_079430 ACLA_079430 ACLA_082070 ACLA_082070 ACLA_082080 ACLA_082080 ACLA_082790 ACLA_082790 ACLA_083320 ACLA_083320 ACLA_085620 ACLA_085620
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_057890Cytoskeleton assembly control protein Sla1, putative. (1164 aa)
myoAMyosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity). (1253 aa)
ACLA_002900Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (696 aa)
ACLA_003120Inositol polyphosphate phosphatase, putative. (1195 aa)
ACLA_003470Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (219 aa)
ACLA_068290Actin cortical patch component, putative. (607 aa)
ACLA_069350SH3 domain protein. (1213 aa)
ACLA_073320Coronin; Belongs to the WD repeat coronin family. (608 aa)
ACLA_042870Actin binding protein, putative. (791 aa)
ACLA_009220BAR domain protein. (261 aa)
ACLA_014250GMF family protein. (141 aa)
ACLA_014630Arp2/3 complex subunit (Arp3), putative; Belongs to the actin family. (439 aa)
pan1Actin cytoskeleton-regulatory complex protein pan1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1485 aa)
ACLA_088280Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
ACLA_094510Actin polymerization protein Bzz1, putative. (740 aa)
ACLA_047060Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
ACLA_048490GTPase activating protein for Arf, putative. (668 aa)
ACLA_052220Transgelin, putative. (621 aa)
ACLA_034100ANTH domain protein. (1043 aa)
ACLA_034240Rho GTPase activator (Rgd1), putative. (662 aa)
ACLA_041720BAR adaptor protein RVS167, putative. (401 aa)
ACLA_097920Actin associated protein Wsp1, putative. (642 aa)
ACLA_098100Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
ACLA_098110Uncharacterized protein. (615 aa)
ACLA_022100Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (410 aa)
ACLA_022440Uncharacterized protein. (655 aa)
end3Actin cytoskeleton-regulatory complex protein end3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (404 aa)
ACLA_022710Adenylyl cyclase-associated protein; Belongs to the CAP family. (529 aa)
ACLA_023960Conserved proline-rich protein. (456 aa)
ACLA_025980Uncharacterized protein. (369 aa)
ACLA_031550F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (266 aa)
ACLA_031870Uncharacterized protein. (1193 aa)
ACLA_079430Actin-bundling protein Sac6, putative. (646 aa)
ACLA_082070Uncharacterized protein. (656 aa)
ACLA_082080F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (264 aa)
ACLA_082790DUF500 and SH3 domain protein. (410 aa)
ACLA_083320VHS domain protein. (405 aa)
ACLA_085620DUF2013 domain-containing protein. (650 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
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