STRINGSTRING
ACLA_024520 ACLA_024520 ACLA_001250 ACLA_001250 dbp3 dbp3 ACLA_070470 ACLA_070470 ACLA_071030 ACLA_071030 erb1 erb1 ACLA_028290 ACLA_028290 ACLA_032220 ACLA_032220 ACLA_032230 ACLA_032230 ACLA_086170 ACLA_086170 ACLA_076020 ACLA_076020 ACLA_076030 ACLA_076030 ACLA_009190 ACLA_009190 TIF6 TIF6 SPB1 SPB1 ACLA_015290 ACLA_015290 ACLA_015830 ACLA_015830 ACLA_015850 ACLA_015850 ACLA_006140 ACLA_006140 nop16 nop16 ytm1 ytm1 nop7 nop7 ACLA_048310 ACLA_048310 nsa2 nsa2 ACLA_037680 ACLA_037680 spb4 spb4 ACLA_096580 ACLA_096580 ACLA_019230 ACLA_019230 drs1 drs1 ACLA_024970 ACLA_024970 ACLA_025090 ACLA_025090 ACLA_026260 ACLA_026260
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_024520Ribosomal RNA processing protein, putative. (332 aa)
ACLA_001250DUF1665 domain protein. (298 aa)
dbp3ATP-dependent RNA helicase dbp3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (503 aa)
ACLA_070470Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (655 aa)
ACLA_071030Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4925 aa)
erb1Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (788 aa)
ACLA_028290Ribosome biogenesis protein Ssf2, putative. (442 aa)
ACLA_03222060S ribosome biogenesis protein Brx1, putative. (357 aa)
ACLA_032230F-box domain protein. (371 aa)
ACLA_086170C2H2 finger domain protein, putative. (111 aa)
ACLA_076020Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (692 aa)
ACLA_07603060S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (207 aa)
ACLA_009190RNA processing factor 1. (436 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (796 aa)
ACLA_015290rRNA processing protein (Ebp2), putative. (371 aa)
ACLA_015830Uncharacterized protein. (403 aa)
ACLA_015850Uncharacterized protein. (404 aa)
ACLA_006140Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
nop16Nucleolar protein 16; Involved in the biogenesis of the 60S ribosomal subunit. (241 aa)
ytm1Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (488 aa)
nop7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (680 aa)
ACLA_048310Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (560 aa)
nsa2Ribosome biogenesis protein nsa2; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity). (265 aa)
ACLA_037680AB hydrolase-1 domain-containing protein. (342 aa)
spb4ATP-dependent rRNA helicase spb4; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2. (639 aa)
ACLA_096580Protein MAK16; Belongs to the MAK16 family. (323 aa)
ACLA_019230Ribosome assembly protein Noc2, putative. (785 aa)
drs1ATP-dependent RNA helicase drs1; ATP-binding RNA helicase involved in ribosome assembly. (826 aa)
ACLA_024970GTP-binding protein. (549 aa)
ACLA_025090PUM-HD domain-containing protein. (699 aa)
ACLA_026260AAA family ATPase/60S ribosome export protein Rix7, putative. (738 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
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