STRINGSTRING
ACLA_060230 ACLA_060230 ACLA_000760 ACLA_000760 ACLA_001240 ACLA_001240 cfd1 cfd1 ACLA_004360 ACLA_004360 ACLA_004390 ACLA_004390 ACLA_069400 ACLA_069400 ACLA_070230 ACLA_070230 ACLA_071340 ACLA_071340 ACLA_072520 ACLA_072520 ACLA_073390 ACLA_073390 ACLA_073930 ACLA_073930 ACLA_074530 ACLA_074530 nbp35 nbp35 ACLA_075250 ACLA_075250 ACLA_075510 ACLA_075510 ACLA_076060 ACLA_076060 ACLA_009470 ACLA_009470 ACLA_011660 ACLA_011660 ACLA_013460 ACLA_013460 ACLA_013620 ACLA_013620 ACLA_017500 ACLA_017500 ACLA_061630 ACLA_061630 ACLA_088900 ACLA_088900 ACLA_088910 ACLA_088910 ACLA_094420 ACLA_094420 NTH1 NTH1 ACLA_065450 ACLA_065450 ACLA_045130 ACLA_045130 ACLA_045230 ACLA_045230 ACLA_046000 ACLA_046000 ACLA_049710 ACLA_049710 ACLA_049870 ACLA_049870 ACLA_050150 ACLA_050150 ACLA_050310 ACLA_050310 nar1 nar1 ACLA_051220 ACLA_051220 ACLA_052290 ACLA_052290 ACLA_034510 ACLA_034510 ACLA_034750 ACLA_034750 ACLA_035280 ACLA_035280 ACLA_037330 ACLA_037330 ACLA_037970 ACLA_037970 ACLA_041730 ACLA_041730 ACLA_096880 ACLA_096880 ACLA_096930 ACLA_096930 ACLA_019200 ACLA_019200 ACLA_021550 ACLA_021550 ACLA_021610 ACLA_021610 ACLA_022630 ACLA_022630 ACLA_025240 ACLA_025240 ACLA_026380 ACLA_026380 cia1 cia1 dre2 dre2 ACLA_027210 ACLA_027210 ACLA_027260 ACLA_027260 ACLA_027760 ACLA_027760 ACLA_027960 ACLA_027960 ACLA_030000 ACLA_030000 ACLA_031070 ACLA_031070 ACLA_031200 ACLA_031200 ACLA_080940 ACLA_080940 ACLA_083040 ACLA_083040 ACLA_085180 ACLA_085180 ACLA_085750 ACLA_085750 ACLA_086180 ACLA_086180
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_060230Aconitase family protein. (743 aa)
ACLA_000760NADH-ubiquinone oxidoreductase; Belongs to the complex I 75 kDa subunit family. (732 aa)
ACLA_0012402Fe-2S iron-sulfur cluster binding domain protein. (201 aa)
cfd1Cytosolic Fe-S cluster assembly factor cfd1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (315 aa)
ACLA_004360TLDc domain-containing protein. (503 aa)
ACLA_004390Pyridine nucleotide-disulphide oxidoreductase, putative. (564 aa)
ACLA_069400Iron-sulfur cluster assembly accessory protein Isa2, putative. (240 aa)
ACLA_0702303-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (780 aa)
ACLA_0713402-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (431 aa)
ACLA_072520Thioredoxin, putative. (270 aa)
ACLA_073390Mitochondrial dihydroxy acid dehydratase, putative. (607 aa)
ACLA_073930NADH-ubiquinone oxidoreductase 49 kDa subunit, putative; Belongs to the complex I 49 kDa subunit family. (474 aa)
ACLA_074530Sulfite reductase, putative. (1522 aa)
nbp35Cytosolic Fe-S cluster assembly factor nbp35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (344 aa)
ACLA_075250Dihydroxy acid dehydratase, putative. (652 aa)
ACLA_075510DNA polymerase. (1105 aa)
ACLA_076060Uncharacterized protein. (421 aa)
ACLA_009470Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (576 aa)
ACLA_011660Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (777 aa)
ACLA_013460Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (299 aa)
ACLA_013620Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (239 aa)
ACLA_017500NADH-ubiquinone oxidoreductase subunit B, putative; Belongs to the complex I 20 kDa subunit family. (225 aa)
ACLA_061630Uncharacterized protein. (261 aa)
ACLA_0889002-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (570 aa)
ACLA_088910Uncharacterized protein. (856 aa)
ACLA_094420Uncharacterized protein. (533 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (421 aa)
ACLA_065450AIF-like mitochondrial oxidoreductase (Nfrl), putative. (668 aa)
ACLA_045130NADH-ubiquinone oxidoreductase subunit B, putative; Belongs to the complex I 20 kDa subunit family. (225 aa)
ACLA_045230Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (93 aa)
ACLA_046000Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (171 aa)
ACLA_049710Mitochondrial chaperone Frataxin, putative. (213 aa)
ACLA_049870Conserved membrane protein, putative. (558 aa)
ACLA_050150NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (496 aa)
ACLA_050310Xanthine dehydrogenase HxA, putative. (1359 aa)
nar1Cytosolic Fe-S cluster assembly factor nar1; Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity). (597 aa)
ACLA_051220DNA replication helicase Dna2, putative. (1679 aa)
ACLA_052290Metallo-beta-lactamase domain protein, putative. (306 aa)
ACLA_034510Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (415 aa)
ACLA_034750DNA polymerase. (1654 aa)
ACLA_035280Radical SAM domain protein. (317 aa)
ACLA_037330DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2229 aa)
ACLA_037970Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (639 aa)
ACLA_041730tRNA splicing protein (Spl1), putative. (517 aa)
ACLA_0968802-methylcitrate dehydratase, putative. (566 aa)
ACLA_096930Biotin synthase, putative. (399 aa)
ACLA_019200Molybdopterin cofactor biosynthetic protein. (698 aa)
ACLA_021550TFIIH complex helicase Rad3, putative. (771 aa)
ACLA_021610Uncharacterized protein. (626 aa)
ACLA_022630Nitrite reductase NiiA. (1103 aa)
ACLA_025240RNase L inhibitor of the ABC superfamily, putative. (633 aa)
ACLA_026380Glutaredoxin domain protein. (279 aa)
cia1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (453 aa)
dre2Fe-S cluster assembly protein dre2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35. Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18. Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (310 aa)
ACLA_027210Glutamate synthase Glt1, putative. (2125 aa)
ACLA_027260Dihydroxy-acid dehydratase, putative. (608 aa)
ACLA_027760Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (799 aa)
ACLA_027960NADH-quinone oxidoreductase, 23 kDa subunit, putative. (228 aa)
ACLA_030000NifU-related protein. (320 aa)
ACLA_031070Mitochondrial dihydroxy acid dehydratase, putative. (607 aa)
ACLA_031200DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
ACLA_080940NADH-ubiquinone dehydrogenase 24 kDa subunit, putative. (268 aa)
ACLA_083040Nucleotide binding protein, putative. (324 aa)
ACLA_085180Flavodoxin and radical SAM domain protein. (778 aa)
ACLA_085750BolA domain protein; Belongs to the BolA/IbaG family. (92 aa)
ACLA_086180Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
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