57 items (Aspergillus clavatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	ACLA_058350	Uncharacterized protein. (1269 aa)
	ACLA_058910	Transcription initiation factor iif, beta subunit. (374 aa)
	ACLA_000810	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (456 aa)
	rpc82	DNA-directed RNA polymerase III subunit rpc3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (635 aa)
	ACLA_001500	Transcription initiation factor TFIID complex 60 kDa subunit. (448 aa)
	ACLA_001520	Transcription initiation factor TFIID subunit beta, putative. (521 aa)
	ACLA_001850	TFIIH complex helicase Ssl2, putative. (823 aa)
	ACLA_004700	Uncharacterized protein. (391 aa)
	ACLA_068800	Uncharacterized protein. (323 aa)
	ACLA_069720	DNA polymerase. (1461 aa)
	ACLA_069970	Uncharacterized protein. (560 aa)
	ACLA_070150	Pol II transcription elongation factor subunit Cdc73, putative. (482 aa)
	ACLA_071910	RNA polymerase II subunit 3. (333 aa)
	ACLA_072600	Bromodomain associated protein. (215 aa)
	ACLA_072610	Transcription initiation factor TFIID subunit 7, putative. (484 aa)
	ACLA_073920	DNA-directed RNA polymerase I and III subunit Rpc40, putative. (374 aa)
	ACLA_074620	Uncharacterized protein. (360 aa)
	ACLA_074630	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	ACLA_075130	DNA-directed RNA polymerase III RPC4, putative. (603 aa)
	ACLA_054010	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (478 aa)
	ACLA_009130	RNA polymerase II transcription elongation factor (Ctr9), putative. (1229 aa)
	ACLA_010290	Cyclin Ccl1, putative; Belongs to the cyclin family. (440 aa)
	ACLA_014170	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (145 aa)
	ACLA_014550	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (286 aa)
	ACLA_014650	Transcription factor TFIIH subunit Tfb4, putative. (386 aa)
	ACLA_016000	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (668 aa)
	ACLA_060570	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (717 aa)
	ACLA_005400	Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily. (404 aa)
	ACLA_005560	DNA-directed RNA polymerase II subunit RPB11a, putative. (165 aa)
	ACLA_092960	RNA polymerase II transcription elongation factor Rtf1p, putative. (605 aa)
	ACLA_065310	Uncharacterized protein. (281 aa)
	ACLA_065700	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (355 aa)
	ACLA_048280	CDK-activating kinase assembly factor MAT1. (382 aa)
	ACLA_050230	DNA polymerase iota, putative. (591 aa)
	ACLA_050750	RNA polymerase II transcription factor, putative. (644 aa)
	ACLA_051000	Metallothionein-I gene transcription activator. (76 aa)
	ACLA_033890	Transcription factor Rba50, putative. (483 aa)
	ACLA_034050	Transcription initiation factor TFIID subunit 12, putative. (630 aa)
	ACLA_039700	Uncharacterized protein. (592 aa)
	ACLA_041280	RNA polymerase II Elongator complex associated protein Kti12, putative. (420 aa)
	ACLA_041900	Bromodomain associated protein. (348 aa)
	ACLA_042010	DNA repair protein Rex1, putative. (72 aa)
	ACLA_095950	DNA-directed RNA polymerase I and III 14 kDa polypeptide. (142 aa)
	ACLA_020630	Transcription factor TFIIA complex subunit Toa1, putative. (402 aa)
	ACLA_020830	Transcription initiation factor TFIID, 31kD subunit, putative. (313 aa)
	ACLA_023760	DUF4211 domain-containing protein. (463 aa)
	ACLA_025040	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (677 aa)
	ACLA_026140	Transcription initiation factor TFIID subunit 13, putative. (170 aa)
	ACLA_026290	Uncharacterized protein. (468 aa)
	ACLA_026620	WD domain protein. (404 aa)
	ACLA_029480	DNA-directed RNA polymerase I, II, and III subunit Rpb6. (161 aa)
	ACLA_031200	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
	ACLA_031570	Transcription initiation factor TFIID subunit, putative. (744 aa)
	ACLA_080290	Transcription factor TFIIE complex alpha subunit, putative. (452 aa)
	ACLA_080350	DNA directed RNA polymerase II 15 kDa subunit, putative. (122 aa)
	ACLA_083810	Transcription factor TFIID complex 145 kDa subunit, putative. (1113 aa)
	ACLA_086380	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (294 aa)

Your Current Organism:

Aspergillus clavatus

NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLA_000810	ACLA_001500	A1C4Q2	A1C4X1	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription initiation factor TFIID complex 60 kDa subunit.	0.923
ACLA_000810	ACLA_001520	A1C4Q2	A1C4X3	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription initiation factor TFIID subunit beta, putative.	0.894
ACLA_000810	ACLA_001850	A1C4Q2	A1C506	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	TFIIH complex helicase Ssl2, putative.	0.999
ACLA_000810	ACLA_004700	A1C4Q2	A1C5T8	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.955
ACLA_000810	ACLA_005400	A1C4Q2	A1CD59	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily.	0.993
ACLA_000810	ACLA_005560	A1C4Q2	A1CD73	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerase II subunit RPB11a, putative.	0.980
ACLA_000810	ACLA_010290	A1C4Q2	A1CA35	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Cyclin Ccl1, putative; Belongs to the cyclin family.	0.991
ACLA_000810	ACLA_014170	A1C4Q2	A1CB62	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.978
ACLA_000810	ACLA_014550	A1C4Q2	A1CBA0	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.871
ACLA_000810	ACLA_014650	A1C4Q2	A1CBB0	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription factor TFIIH subunit Tfb4, putative.	0.999
ACLA_000810	ACLA_020630	A1C4Q2	A1CNY5	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription factor TFIIA complex subunit Toa1, putative.	0.985
ACLA_000810	ACLA_020830	A1C4Q2	A1CP04	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription initiation factor TFIID, 31kD subunit, putative.	0.874
ACLA_000810	ACLA_023760	A1C4Q2	A1CPU1	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DUF4211 domain-containing protein.	0.758
ACLA_000810	ACLA_026140	A1C4Q2	A1CQH6	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription initiation factor TFIID subunit 13, putative.	0.897
ACLA_000810	ACLA_029480	A1C4Q2	A1CRE9	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerase I, II, and III subunit Rpb6.	0.978
ACLA_000810	ACLA_031570	A1C4Q2	A1CS03	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription initiation factor TFIID subunit, putative.	0.874
ACLA_000810	ACLA_034050	A1C4Q2	A1CJ78	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription initiation factor TFIID subunit 12, putative.	0.925
ACLA_000810	ACLA_042010	A1C4Q2	A1CLF5	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA repair protein Rex1, putative.	0.994
ACLA_000810	ACLA_048280	A1C4Q2	A1CHK3	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	CDK-activating kinase assembly factor MAT1.	0.999
ACLA_000810	ACLA_050750	A1C4Q2	A1CI98	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II transcription factor, putative.	0.999