(12 nodes) C2 domain network (Aspergillus clavatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hulA	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (815 aa)
	ACLA_014990	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1112 aa)
	ACLA_005510	C2 domain protein. (586 aa)
	ACLA_093130	Conserved serine proline-rich protein. (905 aa)
	ACLA_065160	C2 domain protein. (1362 aa)
	ACLA_065710	Membrane bound C2 domain protein (Vp115), putative. (1524 aa)
	ACLA_050200	C2 domain protein. (1233 aa)
	ACLA_035860	Phosphoinositide phospholipase C. (649 aa)
	PSD2	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1077 aa)
	ACLA_022180	Phosphoinositide phospholipase C. (1041 aa)
	ACLA_028190	Non-specific serine/threonine protein kinase. (938 aa)
	ACLA_085590	GTPase activating protein (BUD2/CLA2), putative. (1267 aa)

Your Current Organism:

Aspergillus clavatus

NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLA_014990	ACLA_022180	A1CBE3	A1CPD3	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Phosphoinositide phospholipase C.	0.476
ACLA_014990	ACLA_035860	A1CBE3	A1CJQ9	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Phosphoinositide phospholipase C.	0.476
ACLA_022180	ACLA_014990	A1CPD3	A1CBE3	Phosphoinositide phospholipase C.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.476
ACLA_028190	hulA	A1CR23	A1CQG2	Non-specific serine/threonine protein kinase.	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	0.416
ACLA_035860	ACLA_014990	A1CJQ9	A1CBE3	Phosphoinositide phospholipase C.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.476
hulA	ACLA_028190	A1CQG2	A1CR23	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	Non-specific serine/threonine protein kinase.	0.416