STRINGSTRING
ACLA_036380 ACLA_036380 ACLA_035140 ACLA_035140 ACLA_034880 ACLA_034880 dhh1 dhh1 ACLA_052440 ACLA_052440 ACLA_052420 ACLA_052420 has1 has1 ACLA_050000 ACLA_050000 prp28 prp28 ded1 ded1 ACLA_046550 ACLA_046550 ACLA_046470 ACLA_046470 ACLA_065140 ACLA_065140 dbp5 dbp5 ACLA_090770 ACLA_090770 ACLA_089690 ACLA_089690 ACLA_088330 ACLA_088330 ACLA_007220 ACLA_007220 ACLA_005520 ACLA_005520 ACLA_015650 ACLA_015650 dcl1 dcl1 ACLA_014690 ACLA_014690 ACLA_014220 ACLA_014220 dbp7 dbp7 ACLA_013720 ACLA_013720 ACLA_013710 ACLA_013710 ACLA_013700 ACLA_013700 ACLA_009930 ACLA_009930 ACLA_009920 ACLA_009920 ACLA_009640 ACLA_009640 ino80 ino80 dcl2 dcl2 ACLA_055550 ACLA_055550 ACLA_054600 ACLA_054600 ACLA_075100 ACLA_075100 dbp9 dbp9 ACLA_072170 ACLA_072170 ACLA_069810 ACLA_069810 dbp2 dbp2 ACLA_069040 ACLA_069040 dbp3 dbp3 fal1 fal1 ACLA_001850 ACLA_001850 ACLA_058130 ACLA_058130 rrp3 rrp3 ACLA_026230 ACLA_026230 prp5 prp5 ACLA_025250 ACLA_025250 ACLA_022450 ACLA_022450 drs1 drs1 ACLA_020240 ACLA_020240 ACLA_019750 ACLA_019750 rok1 rok1 ACLA_018570 ACLA_018570 sub2 sub2 ACLA_096270 ACLA_096270 spb4 spb4 dbp8 dbp8 tif1 tif1 ACLA_086540 ACLA_086540 ACLA_086330 ACLA_086330 ACLA_086150 ACLA_086150 dbp10 dbp10 dbp4 dbp4 mak5 mak5 ACLA_083170 ACLA_083170 ACLA_081040 ACLA_081040 ACLA_080930 ACLA_080930 mrh4 mrh4 ACLA_079870 ACLA_079870 ACLA_079710 ACLA_079710 mph1 mph1 ACLA_030750 ACLA_030750 ACLA_029390 ACLA_029390 ACLA_028760 ACLA_028760
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_036380SNF2 family helicase/ATPase, putative. (1131 aa)
ACLA_035140DEAD/DEAH box RNA helicase, putative; Belongs to the DEAD box helicase family. (584 aa)
ACLA_034880DEAD/DEAH box helicase, putative. (1761 aa)
dhh1ATP-dependent RNA helicase dhh1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (503 aa)
ACLA_052440SNF2 family helicase/ATPase, putative. (1121 aa)
ACLA_052420Chromatin remodeling complex subunit (Chd3), putative. (1522 aa)
has1ATP-dependent RNA helicase has1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. (625 aa)
ACLA_050000SNF2 family helicase, putative. (1190 aa)
prp28Pre-mRNA-splicing ATP-dependent RNA helicase prp28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (798 aa)
ded1ATP-dependent RNA helicase ded1; ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. (681 aa)
ACLA_046550Helicase C-terminal domain protein. (432 aa)
ACLA_046470ATP dependent RNA helicase (Dob1), putative. (1082 aa)
ACLA_065140SNF2 family helicase/ATPase (Swr1), putative. (1687 aa)
dbp5ATP-dependent RNA helicase dbp5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity). (487 aa)
ACLA_090770DNA excision repair protein (Rad26L), putative. (1011 aa)
ACLA_089690RecQ family helicase MusN. (1542 aa)
ACLA_088330SNF2 family helicase/ATPase, putative. (1473 aa)
ACLA_007220DEAD/DEAH box helicase, putative. (539 aa)
ACLA_005520DNA excision repair protein Rad16, putative. (842 aa)
ACLA_015650DNA excision repair protein (Rad5), putative. (1252 aa)
dcl1ATP-dependent helicase dcl1; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity); Belongs to the helicase family. Dicer subfamily. (1534 aa)
ACLA_014690Pre-mRNA splicing factor RNA helicase (Prp43), putative. (772 aa)
ACLA_014220Nucleosome remodeling complex ATPase subunit (Snf2h), putative. (657 aa)
dbp7ATP-dependent RNA helicase dbp7; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs. (755 aa)
ACLA_013720Mitochondrial ATP-dependent RNA helicase Suv3, putative. (633 aa)
ACLA_013710DNA repair helicase rad5,16. (1174 aa)
ACLA_013700RNA helicase-like splicing factor (HRH1), putative. (1231 aa)
ACLA_009930SNF2 family helicase/ATPase, putative. (1818 aa)
ACLA_009920SNF2 family helicase, putative. (953 aa)
ACLA_009640RSC complex subunit (Sth1), putative. (1379 aa)
ino80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1707 aa)
dcl2ATP-dependent helicase dcl2; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity); Belongs to the helicase family. Dicer subfamily. (1389 aa)
ACLA_055550DEAD/DEAH box helicase, putative. (2007 aa)
ACLA_054600DNA repair protein Rhp26/Rad26, putative. (1221 aa)
ACLA_075100DEAD/DEAH box helicase, putative. (1353 aa)
dbp9ATP-dependent RNA helicase dbp9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily. (621 aa)
ACLA_072170SNF2 family helicase/ATPase, putative. (1179 aa)
ACLA_069810DEAD/DEAH box helicase, putative. (1196 aa)
dbp2ATP-dependent RNA helicase dbp2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing. (549 aa)
ACLA_069040DEAD/DEAH box RNA helicase (Ski2), putative. (1292 aa)
dbp3ATP-dependent RNA helicase dbp3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (503 aa)
fal1ATP-dependent RNA helicase fal1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity). Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily. (399 aa)
ACLA_001850TFIIH complex helicase Ssl2, putative. (823 aa)
ACLA_058130Pre-mRNA splicing helicase, putative. (2209 aa)
rrp3ATP-dependent rRNA helicase rrp3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA. (473 aa)
ACLA_026230ATP dependent RNA helicase, putative. (672 aa)
prp5Pre-mRNA-processing ATP-dependent RNA helicase prp5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1192 aa)
ACLA_025250Chromodomain helicase (Chd1), putative. (1506 aa)
ACLA_022450SNF2 family helicase/ATPase PasG, putative. (892 aa)
drs1ATP-dependent RNA helicase drs1; ATP-binding RNA helicase involved in ribosome assembly. (826 aa)
ACLA_020240DsDNA-dependent ATPase (Rad54b), putative. (976 aa)
ACLA_019750DEAD box RNA helicase HelA, putative; Belongs to the DEAD box helicase family. (663 aa)
rok1ATP-dependent RNA helicase rok1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. (738 aa)
ACLA_018570DEAD/DEAH box helicase, putative. (848 aa)
sub2ATP-dependent RNA helicase sub2; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (441 aa)
ACLA_096270DEAH-box RNA helicase (Dhr1), putative. (1219 aa)
spb4ATP-dependent rRNA helicase spb4; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2. (639 aa)
dbp8ATP-dependent RNA helicase dbp8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily. (523 aa)
tif1ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (398 aa)
ACLA_086540SWI/SNF family DNA-dependent ATPase Ris1, putative. (1253 aa)
ACLA_086330DEAD/DEAH box DNA helicase (Mer3), putative. (1432 aa)
ACLA_086150SNF2 family N-terminal domain protein. (682 aa)
dbp10ATP-dependent RNA helicase dbp10; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (935 aa)
dbp4ATP-dependent RNA helicase dbp4; ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity). (823 aa)
mak5ATP-dependent RNA helicase mak5; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily. (774 aa)
ACLA_083170SNF2 family helicase/ATPase, putative. (1147 aa)
ACLA_081040ATP-dependent RNA helicase (Hrh1), putative. (826 aa)
ACLA_080930C-5 cytosine-specific DNA methylase, putative. (2150 aa)
mrh4ATP-dependent RNA helicase mrh4, mitochondrial; ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA (By similarity); Belongs to the DEAD box helicase family. MRH4 subfamily. (632 aa)
ACLA_079870ATP dependent RNA helicase, putative. (1460 aa)
ACLA_079710mRNA splicing factor RNA helicase (Cdc28), putative. (1129 aa)
mph1ATP-dependent DNA helicase mph1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1119 aa)
ACLA_030750mRNA splicing factor RNA helicase (Prp16), putative. (911 aa)
ACLA_029390DNA-directed DNA polymerase theta, putative. (940 aa)
ACLA_028760TBP associated factor (Mot1), putative. (1901 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
Server load: low (28%) [HD]