STRINGSTRING
ACLA_063030 ACLA_063030 ACLA_076490 ACLA_076490 ACLA_004770 ACLA_004770 ACLA_002670 ACLA_002670 ACLA_087700 ACLA_087700 ACLA_023380 ACLA_023380 ACLA_098920 ACLA_098920 ACLA_098370 ACLA_098370 ccsA ccsA ACLA_077660 ACLA_077660 ACLA_042410 ACLA_042410 ACLA_045110 ACLA_045110 ACLA_094600 ACLA_094600 ACLA_093760 ACLA_093760 patK patK ACLA_008090 ACLA_008090 ACLA_063870 ACLA_063870 ACLA_043310 ACLA_043310 ACLA_061390 ACLA_061390 ACLA_061310 ACLA_061310 ACLA_060580 ACLA_060580 ACLA_055790 ACLA_055790 ACLA_055680 ACLA_055680 ACLA_043440 ACLA_043440
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_063030Polyketide synthase, putative. (2556 aa)
ACLA_076490Polyketide synthetase PksP. (2145 aa)
ACLA_004770Hybrid NRPS/PKS enzyme, putative. (4007 aa)
ACLA_002670Polyketide synthase, putative. (2628 aa)
ACLA_087700Polyketide synthase, putative. (2444 aa)
ACLA_023380Equisetin synthetase, putative. (3948 aa)
ACLA_098920Polyketide synthase, putative. (2559 aa)
ACLA_098370Polyketide synthase, putative. (2582 aa)
ccsAPolyketide synthase-nonribosomal peptide synthetase; Hybrid PKS-NRPS synthetase; part of the gene cluster that mediates the biosynthesis of the mycotoxins cytochalasins E and K. The hybrid PKS-NRPS synthetase ccsA and the enoyl reductase ccsC are responsible for fusion of phenylalanine with an octaketide backbone and subsequent release of the stable tetramic acid precursor. The polyketide synthase module (PKS) of the PKS-NRPS ccsA is responsible for the synthesis of the octaketide backbone. The downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the octaketid [...] (4043 aa)
ACLA_077660Hybrid NRPS/PKS enzyme, putative. (3943 aa)
ACLA_042410Polyketide synthase, putative. (2437 aa)
ACLA_045110Malonyl CoA-acyl carrier protein transacylase, putative. (341 aa)
ACLA_094600Polyketide synthase, putative. (2599 aa)
ACLA_093760Fatty acid synthase subunit beta, putative; Belongs to the fungal fatty acid synthetase subunit beta family. (1983 aa)
patK6-methylcalicylic acide synthase; 6-methylcalicylic acide synthase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. The pathway begins with the synthesis of 6- methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6- methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These fir [...] (1720 aa)
ACLA_008090Polyketide synthase, putative. (2597 aa)
ACLA_063870Polyketide synthase, putative. (2421 aa)
ACLA_043310Polyketide synthase, putative. (1749 aa)
ACLA_061390Polyketide synthase, putative. (1914 aa)
ACLA_061310Polyketide synthase, putative. (2561 aa)
ACLA_060580Fatty acid synthase beta subunit, putative; Belongs to the fungal fatty acid synthetase subunit beta family. (2092 aa)
ACLA_055790Polyketide synthase, putative. (2517 aa)
ACLA_055680Polyketide synthase, putative. (2934 aa)
ACLA_043440Polyketide synthase, putative. (2495 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.