(40 nodes) Chloramphenicol acetyltransferase-like domain superfamily network (Aspergillus clavatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ACLA_061190	Nonribosomal peptide synthase SidE. (2115 aa)
	ACLA_061260	Transferase family protein. (493 aa)
	ACLA_061540	Transferase family protein. (440 aa)
	ACLA_093780	Nonribosomal peptide synthase, putative. (6199 aa)
	ACLA_066550	NRPS-like enzyme, putative. (596 aa)
	ACLA_025160	Nonribosomal peptide synthase Pes1. (6262 aa)
	ACLA_023730	Trichothecene 3-O-acetyltransferase, putative. (459 aa)
	ACLA_023380	Equisetin synthetase, putative. (3948 aa)
	ACLA_066710	NRPS-like enzyme, putative. (1227 aa)
	ACLA_066880	NRPS-like enzyme, putative. (430 aa)
	ACLA_051040	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (474 aa)
	ACLA_033390	Dihydrolipoamide succinyltransferase, putative. (461 aa)
	ACLA_061830	Transferase family protein. (447 aa)
	ACLA_063930	Transferase family protein. (472 aa)
	ACLA_007420	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (851 aa)
	ACLA_008060	Enoyl-CoA hydratase/isomerase family protein, putative; Belongs to the enoyl-CoA hydratase/isomerase family. (804 aa)
	ACLA_077660	Hybrid NRPS/PKS enzyme, putative. (3943 aa)
	ccsA	Polyketide synthase-nonribosomal peptide synthetase; Hybrid PKS-NRPS synthetase; part of the gene cluster that mediates the biosynthesis of the mycotoxins cytochalasins E and K. The hybrid PKS-NRPS synthetase ccsA and the enoyl reductase ccsC are responsible for fusion of phenylalanine with an octaketide backbone and subsequent release of the stable tetramic acid precursor. The polyketide synthase module (PKS) of the PKS-NRPS ccsA is responsible for the synthesis of the octaketide backbone. The downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the octaketid [...] (4043 aa)
	ACLA_095980	Nonribosomal peptide synthase, putative. (3921 aa)
	ACLA_059530	Nonribosomal peptide synthase, putative. (5321 aa)
	ACLA_098420	Nonribosomal peptide synthase, putative. (8202 aa)
	ACLA_017890	Nonribosomal peptide synthase, putative. (4064 aa)
	ACLA_017900	Nonribosomal peptide synthase, putative. (1113 aa)
	ACLA_023130	Carnitine acetyl transferase. (824 aa)
	ACLA_097640	Uncharacterized protein. (461 aa)
	ACLA_004770	Hybrid NRPS/PKS enzyme, putative. (4007 aa)
	ACLA_071420	Carnitine acetyl transferase; Belongs to the carnitine/choline acetyltransferase family. (610 aa)
	ACLA_076770	Nonribosomal peptide synthase, putative. (3502 aa)
	ACLA_043470	LysR family regulatory protein, putative. (508 aa)
	ACLA_043770	Uncharacterized protein. (503 aa)
	ACLA_044390	Nonribosomal peptide synthase, putative. (2511 aa)
	ACLA_055680	Polyketide synthase, putative. (2934 aa)
	ACLA_055700	Trichothecene biosynthesis acetyltransferase, putative. (487 aa)
	ACLA_061000	Nonribosomal peptide synthase SidD. (2066 aa)
	ACLA_059750	Acetyltransferase, putative. (441 aa)
	ACLA_059680	Acetyltransferase, putative. (473 aa)
	ACLA_087850	Trichothecene biosynthesis acetyltransferase, putative. (440 aa)
	ACLA_087830	Uncharacterized protein. (457 aa)
	ACLA_079690	Nonribosomal siderophore peptide synthase, putative. (5034 aa)
	ACLA_033230	Uncharacterized protein. (408 aa)

Your Current Organism:

Aspergillus clavatus

NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLA_007420	ACLA_033390	A1CDQ6	A1CJ12	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoamide succinyltransferase, putative.	0.927
ACLA_007420	ACLA_051040	A1CDQ6	A1CIC7	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.723
ACLA_017900	ACLA_066550	A1CN66	A1CGD9	Nonribosomal peptide synthase, putative.	NRPS-like enzyme, putative.	0.594
ACLA_023130	ACLA_071420	A1CPM8	A1C6T8	Carnitine acetyl transferase.	Carnitine acetyl transferase; Belongs to the carnitine/choline acetyltransferase family.	0.947
ACLA_023380	ACLA_066710	A1CPQ3	A1CGF5	Equisetin synthetase, putative.	NRPS-like enzyme, putative.	0.477
ACLA_033390	ACLA_007420	A1CJ12	A1CDQ6	Dihydrolipoamide succinyltransferase, putative.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.927
ACLA_033390	ACLA_051040	A1CJ12	A1CIC7	Dihydrolipoamide succinyltransferase, putative.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.742
ACLA_051040	ACLA_007420	A1CIC7	A1CDQ6	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.723
ACLA_051040	ACLA_033390	A1CIC7	A1CJ12	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoamide succinyltransferase, putative.	0.742
ACLA_055680	ACLA_066710	A1C9J6	A1CGF5	Polyketide synthase, putative.	NRPS-like enzyme, putative.	0.477
ACLA_059750	ACLA_063930	A1C4G8	A1CD15	Acetyltransferase, putative.	Transferase family protein.	0.411
ACLA_063930	ACLA_059750	A1CD15	A1C4G8	Transferase family protein.	Acetyltransferase, putative.	0.411
ACLA_066550	ACLA_017900	A1CGD9	A1CN66	NRPS-like enzyme, putative.	Nonribosomal peptide synthase, putative.	0.594
ACLA_066710	ACLA_023380	A1CGF5	A1CPQ3	NRPS-like enzyme, putative.	Equisetin synthetase, putative.	0.477
ACLA_066710	ACLA_055680	A1CGF5	A1C9J6	NRPS-like enzyme, putative.	Polyketide synthase, putative.	0.477
ACLA_066710	ACLA_066880	A1CGF5	A1CGH2	NRPS-like enzyme, putative.	NRPS-like enzyme, putative.	0.948
ACLA_066710	ACLA_077660	A1CGF5	A1CLP0	NRPS-like enzyme, putative.	Hybrid NRPS/PKS enzyme, putative.	0.477
ACLA_066710	ccsA	A1CGF5	A1CLY8	NRPS-like enzyme, putative.	Polyketide synthase-nonribosomal peptide synthetase; Hybrid PKS-NRPS synthetase; part of the gene cluster that mediates the biosynthesis of the mycotoxins cytochalasins E and K. The hybrid PKS-NRPS synthetase ccsA and the enoyl reductase ccsC are responsible for fusion of phenylalanine with an octaketide backbone and subsequent release of the stable tetramic acid precursor. The polyketide synthase module (PKS) of the PKS-NRPS ccsA is responsible for the synthesis of the octaketide backbone. The downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the octaketid [...]	0.477
ACLA_066880	ACLA_066710	A1CGH2	A1CGF5	NRPS-like enzyme, putative.	NRPS-like enzyme, putative.	0.948
ACLA_071420	ACLA_023130	A1C6T8	A1CPM8	Carnitine acetyl transferase; Belongs to the carnitine/choline acetyltransferase family.	Carnitine acetyl transferase.	0.947