43 items (Aspergillus clavatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACLA_058720	Uncharacterized protein. (508 aa)
	ACLA_058730	RNA polymerase II subunit 7. (169 aa)
	ACLA_058910	Transcription initiation factor iif, beta subunit. (374 aa)
	ACLA_000810	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (456 aa)
	ACLA_001850	TFIIH complex helicase Ssl2, putative. (823 aa)
	ACLA_004700	Uncharacterized protein. (391 aa)
	ACLA_069970	Uncharacterized protein. (560 aa)
	ACLA_070150	Pol II transcription elongation factor subunit Cdc73, putative. (482 aa)
	ACLA_071490	Uncharacterized protein. (706 aa)
	ACLA_071910	RNA polymerase II subunit 3. (333 aa)
	ACLA_054010	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (478 aa)
	ACLA_009130	RNA polymerase II transcription elongation factor (Ctr9), putative. (1229 aa)
	ACLA_010010	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (120 aa)
	ACLA_010290	Cyclin Ccl1, putative; Belongs to the cyclin family. (440 aa)
	ACLA_014170	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (145 aa)
	ACLA_014650	Transcription factor TFIIH subunit Tfb4, putative. (386 aa)
	ACLA_060570	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (717 aa)
	ACLA_005400	Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily. (404 aa)
	ACLA_005560	DNA-directed RNA polymerase II subunit RPB11a, putative. (165 aa)
	ACLA_091690	NDC10_II domain-containing protein. (166 aa)
	ACLA_092960	RNA polymerase II transcription elongation factor Rtf1p, putative. (605 aa)
	ACLA_064940	DNA-directed RNA polymerases N/8 kDa subunit superfamily. (74 aa)
	ACLA_065630	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1257 aa)
	ACLA_047860	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1045 aa)
	ACLA_048280	CDK-activating kinase assembly factor MAT1. (382 aa)
	ACLA_050750	RNA polymerase II transcription factor, putative. (644 aa)
	ACLA_051000	Metallothionein-I gene transcription activator. (76 aa)
	ACLA_051120	TPR domain protein. (400 aa)
	ACLA_033860	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1421 aa)
	ACLA_035980	Polymerase (RNA) II (DNA directed) polypeptide D. (148 aa)
	ACLA_039310	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (826 aa)
	ACLA_039700	Uncharacterized protein. (592 aa)
	ACLA_042010	DNA repair protein Rex1, putative. (72 aa)
	ACLA_095410	Cap binding protein. (848 aa)
	ACLA_020720	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1765 aa)
	ACLA_021310	RNA polymerase subunit. (234 aa)
	ACLA_021550	TFIIH complex helicase Rad3, putative. (771 aa)
	ACLA_023200	Transcriptional elongation factor Iws1, putative. (450 aa)
	ACLA_026290	Uncharacterized protein. (468 aa)
	ACLA_029480	DNA-directed RNA polymerase I, II, and III subunit Rpb6. (161 aa)
	ACLA_080350	DNA directed RNA polymerase II 15 kDa subunit, putative. (122 aa)
	ACLA_080400	Nuclear cap-binding protein subunit 2. (138 aa)
	ACLA_083000	Uncharacterized protein. (720 aa)

Your Current Organism:

Aspergillus clavatus

NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLA_000810	ACLA_001850	A1C4Q2	A1C506	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	TFIIH complex helicase Ssl2, putative.	0.999
ACLA_000810	ACLA_004700	A1C4Q2	A1C5T8	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.955
ACLA_000810	ACLA_005400	A1C4Q2	A1CD59	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily.	0.993
ACLA_000810	ACLA_005560	A1C4Q2	A1CD73	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerase II subunit RPB11a, putative.	0.980
ACLA_000810	ACLA_010010	A1C4Q2	A1CA10	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.870
ACLA_000810	ACLA_010290	A1C4Q2	A1CA35	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Cyclin Ccl1, putative; Belongs to the cyclin family.	0.991
ACLA_000810	ACLA_014170	A1C4Q2	A1CB62	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.978
ACLA_000810	ACLA_014650	A1C4Q2	A1CBB0	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Transcription factor TFIIH subunit Tfb4, putative.	0.999
ACLA_000810	ACLA_020720	A1C4Q2	A1CNZ4	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.978
ACLA_000810	ACLA_021310	A1C4Q2	A1CP51	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase subunit.	0.978
ACLA_000810	ACLA_021550	A1C4Q2	A1CP70	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	TFIIH complex helicase Rad3, putative.	0.999
ACLA_000810	ACLA_029480	A1C4Q2	A1CRE9	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerase I, II, and III subunit Rpb6.	0.978
ACLA_000810	ACLA_035980	A1C4Q2	A1CJS1	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Polymerase (RNA) II (DNA directed) polypeptide D.	0.982
ACLA_000810	ACLA_042010	A1C4Q2	A1CLF5	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA repair protein Rex1, putative.	0.994
ACLA_000810	ACLA_048280	A1C4Q2	A1CHK3	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	CDK-activating kinase assembly factor MAT1.	0.999
ACLA_000810	ACLA_050750	A1C4Q2	A1CI98	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II transcription factor, putative.	0.999
ACLA_000810	ACLA_051000	A1C4Q2	A1CIC3	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Metallothionein-I gene transcription activator.	0.978
ACLA_000810	ACLA_054010	A1C4Q2	A1C931	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999
ACLA_000810	ACLA_058720	A1C4Q2	A1C470	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.879
ACLA_000810	ACLA_058730	A1C4Q2	A1C471	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II subunit 7.	0.973